Results 31 to 40 of about 4,715 (225)
Trends in Peptide and Protein Sciences, 2021 One of the common studies on industrial proteins is to study the RNA Folding and stability, protein stability, physicochemical properties and conformational structure. In our previous proteomics study, Metallopeptidase (MP) was isolated from Lactobacillus casei, which in this study, it was evaluated with RNA fold, Protparam, I-TASSER and Phyre2 web ...
Dadfarma, Narges +3 more
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Molecules, 2020 Kombucha, also known as the Manchurian mushroom, is a symbiotic culture of bacteria and yeast, the so-called SCOBY. This paper presents a comprehensive evaluation of the ferments obtained from green coffee beans after different fermentation times with ...
Nizioł-Łukaszewska Zofia +6 more
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Proteomic characterization of Naja mandalayensis venom
Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background Naja mandalayensis is a spitting cobra from Myanmar. To the best of our knowledge, no studies on this venom composition have been conducted so far.
Emídio Beraldo Neto +3 more
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Proenzyme Structure and Activation of Astacin Metallopeptidase [PDF]
Journal of Biological Chemistry, 2010 Proteolysis is regulated by inactive (latent) zymogens, with a prosegment preventing access of substrates to the active-site cleft of the enzyme. How latency is maintained often depends on the catalytic mechanism of the protease. For example, in several families of the metzincin metallopeptidases, a "cysteine switch" mechanism involves a conserved ...
Guevara, T. +5 more
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Identification and Characterization of Burkholderia pseudomallei K96243 Serine and Metallopeptidases [PDF]
, 2012 Burkholderia pseudomallei K96243, the causative agent of melioidosis, is reported to produce various extracellular products, including proteases. The role of these proteases in the melioidosis, however, remains obscure.
Muhamad Bunnori, Noraslinda +2 more
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Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia
Advanced Science, 2022 Severe infectious diseases, such as coronavirus disease 2019 (COVID‐19), can induce hypercytokinemia and multiple organ failure. In spite of the growing demand for peptide therapeutics against infectious diseases, current small molecule‐based strategies ...
Hyelim Kim +12 more
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Architecture and function of metallopeptidase catalytic domains [PDF]
Protein Science, 2013 AbstractThe cleavage of peptide bonds by metallopeptidases (MPs) is essential for life. These ubiquitous enzymes participate in all major physiological processes, and so their deregulation leads to diseases ranging from cancer and metastasis, inflammation, and microbial infection to neurological insults and cardiovascular disorders.
Nýria Cerdý-Costa +1 more
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Role of Angiopoietins in Development of Cancer and Neoplasia Associated with Viral Infection
Cells, 2020 Angiopoietin/tyrosine protein kinase receptor Tie-2 signaling in endothelial cells plays an essential role in angiogenesis and wound healing. Angiopoietin-1 (Ang-1) is crucial for blood vessel maturation while angiopoietin-2 (Ang-2), in collaboration ...
Xiaolan Yu, Fengchun Ye
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Bacillus licheniformis BlaR1 L3 loop is a zinc metalloprotease activated by self-proteolysis. [PDF]
PLoS ONE, 2012 In Bacillus licheniformis 749/I, BlaP β-lactamase is induced by the presence of a β-lactam antibiotic outside the cell. The first step in the induction mechanism is the detection of the antibiotic by the membrane-bound penicillin receptor BlaR1 that is ...
Stéphanie Berzigotti +4 more
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, 2022 O escorpionismo é um sério problema de saúde pública. O envenenamento pelo escorpião amarelo, Tityus serrulatus, causa dor intensa e em casos graves pode acarretar manifestações sistêmicas, edema pulmonar e insuficiência cardíaca, podendo ser fatal ...
Silva, Cristiane Castilho Fernandes da
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