Results 81 to 90 of about 4,715 (225)
Functions and substrates of plastoglobule-localized metallopeptidase PGM48 [PDF]
Plastoglobules (PGs) in chloroplasts are monolayer lipid-protein particles attached to thylakoids. The size and number of PGs per chloroplast respond dynamically to abiotic environmental stresses and developmental transitions. During senescence, the thylakoid membranes and its constituents are dismantled in controlled fashion. Leaf senescence coincides
Nazmul H. Bhuiyan, Klaas J. van Wijk
openaire +2 more sources
Divergent regulation of zinc metallopeptidases by shear stress in macrovascular endothelial cells via an NADPH oxidase - superoxide pathway [PDF]
Introduction: The hemodynamic environment of blood vessels is a crucial feature of endothelium-mediated vasoregulation. Flow-associated laminar shear stress (LSS) imparts an atheroprotective stimulus on the vascular endothelium, causing realignment of ...
Guinan, Anthony F.
core +1 more source
Although omics studies have indicated presence of proteases on the Tityus serrulatus venom (TsV), little is known about the function of these molecules.
Daniela Cajado-Carvalho +7 more
doaj +1 more source
Gallic acid regulates immune response in a mouse model of rheumatoid arthritis
Introduction Previous studies revealed that gallic acid (GA) exerts anti‐inflammation and immuno‐regulatory properties. This study aims to explore the pharmacological activities of GA in collagen‐induced arthritis (CIA) mouse model.
Siqin Liu, Jiajia Li, Le‐heng Feng
doaj +1 more source
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu +23 more
wiley +1 more source
Secretopathies emerge as a new class of neurocristopathies
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
wiley +1 more source
Fermentation enhances nutritional & techno‐functional properties of plant protein. Three distinct stages of fermentation impact on different aspects of plant protein. Fermentation induces flavors modulation through new organic compounds formation. Plant protein fermentation improves their utility in food applications.
Disha +3 more
wiley +1 more source
Inhibition of zinc metallopeptidases in cardiovascular disease - From unity to trinity, or duality?
The fusion of therapeutics and diagnostic medicine in an effort to provide individualized pharmacotherapy frequently requires the manipulation of drugs that target different enzymes and receptors. To this end, and as a strategy to increase the efficiency
Yiotakis, A. +3 more
core +1 more source
Leptospirosis is an invasive infectious and systemic inflammatory disease
Pathogenic Leptospira species are the causative agents of leptospirosis, a world-spreading zoonotic infectious disease. The pathogens possess a powerful invasiveness by invading human body through mucosal/skin barriers, rapid entry into bloodstream to ...
Ai-Hua Sun, Xiao-Xiang Liu, Jie Yan
doaj +1 more source
Sequential Cleavage by Metallopeptidases and Proteasomes Is Involved in Processing HIV-1 ENV Epitope for Endogenous MHC Class I Antigen Presentation [PDF]
Antigenic peptides derived from viral proteins by multiple proteolytic cleavages are bound by MHC class I molecules and recognized by CTL. Processing predominantly takes place in the cytosol of infected cells by the action of proteasomes.
Beatriz C. Gil-Torregrosa +7 more
core +1 more source

