Results 81 to 90 of about 4,715 (225)

Functions and substrates of plastoglobule-localized metallopeptidase PGM48 [PDF]

open access: yesPlant Signaling & Behavior, 2017
Plastoglobules (PGs) in chloroplasts are monolayer lipid-protein particles attached to thylakoids. The size and number of PGs per chloroplast respond dynamically to abiotic environmental stresses and developmental transitions. During senescence, the thylakoid membranes and its constituents are dismantled in controlled fashion. Leaf senescence coincides
Nazmul H. Bhuiyan, Klaas J. van Wijk
openaire   +2 more sources

Divergent regulation of zinc metallopeptidases by shear stress in macrovascular endothelial cells via an NADPH oxidase - superoxide pathway [PDF]

open access: yes, 2012
Introduction: The hemodynamic environment of blood vessels is a crucial feature of endothelium-mediated vasoregulation. Flow-associated laminar shear stress (LSS) imparts an atheroprotective stimulus on the vascular endothelium, causing realignment of ...
Guinan, Anthony F.
core   +1 more source

Purification and Biochemical Characterization of TsMS 3 and TsMS 4: Neuropeptide-Degrading Metallopeptidases in the Tityus serrulatus Venom

open access: yesToxins, 2019
Although omics studies have indicated presence of proteases on the Tityus serrulatus venom (TsV), little is known about the function of these molecules.
Daniela Cajado-Carvalho   +7 more
doaj   +1 more source

Gallic acid regulates immune response in a mouse model of rheumatoid arthritis

open access: yesImmunity, Inflammation and Disease, 2023
Introduction Previous studies revealed that gallic acid (GA) exerts anti‐inflammation and immuno‐regulatory properties. This study aims to explore the pharmacological activities of GA in collagen‐induced arthritis (CIA) mouse model.
Siqin Liu, Jiajia Li, Le‐heng Feng
doaj   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu   +23 more
wiley   +1 more source

Secretopathies emerge as a new class of neurocristopathies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira   +3 more
wiley   +1 more source

Microbial Interventions in Processing of Plant Based Proteins: Unlocking Extraction Dynamics and Functionality for Human Health

open access: yesFood Bioengineering, EarlyView.
Fermentation enhances nutritional & techno‐functional properties of plant protein. Three distinct stages of fermentation impact on different aspects of plant protein. Fermentation induces flavors modulation through new organic compounds formation. Plant protein fermentation improves their utility in food applications.
Disha   +3 more
wiley   +1 more source

Inhibition of zinc metallopeptidases in cardiovascular disease - From unity to trinity, or duality?

open access: yes, 2009
The fusion of therapeutics and diagnostic medicine in an effort to provide individualized pharmacotherapy frequently requires the manipulation of drugs that target different enzymes and receptors. To this end, and as a strategy to increase the efficiency
Yiotakis, A.   +3 more
core   +1 more source

Leptospirosis is an invasive infectious and systemic inflammatory disease

open access: yesBiomedical Journal, 2020
Pathogenic Leptospira species are the causative agents of leptospirosis, a world-spreading zoonotic infectious disease. The pathogens possess a powerful invasiveness by invading human body through mucosal/skin barriers, rapid entry into bloodstream to ...
Ai-Hua Sun, Xiao-Xiang Liu, Jie Yan
doaj   +1 more source

Sequential Cleavage by Metallopeptidases and Proteasomes Is Involved in Processing HIV-1 ENV Epitope for Endogenous MHC Class I Antigen Presentation [PDF]

open access: yes, 2000
Antigenic peptides derived from viral proteins by multiple proteolytic cleavages are bound by MHC class I molecules and recognized by CTL. Processing predominantly takes place in the cytosol of infected cells by the action of proteasomes.
Beatriz C. Gil-Torregrosa   +7 more
core   +1 more source

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