Results 11 to 20 of about 182,335 (266)
Biomolecules, 2021 Matrix metalloproteinases (MMPs) are proteolytic enzymes that have been associated with the pathogenesis of inflammatory diseases and obesity. Adipose tissue in turn is an active endocrine organ capable of secreting a range of proinflammatory mediators ...
Priscila Motta Janovits +3 more
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The ADAMTS metalloproteinases [PDF]
Biochemical Journal, 2005 The ADAMTSs (adisintegrin and metalloproteinase with thrombospondin motifs) are a group of proteases that are found both in mammals and invertebrates. Since the prototype ADAMTS-1 was first described in 1997, there has been a rapidly expanding body of literature describing this gene family and the proteins they encode.
Porter, Sarah +3 more
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Microorganisms, 2023 In this study, we evaluated the in vitro anti-biofilm, antibacterial, and anti-inflammatory activity of Weissella cibaria CMU (CMU), an oral probiotic, against periodontopathogens.
Mi-Sun Kang, Geun-Yeong Park, A-Reum Lee
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Metalloproteinases in melanoma
European Journal of Cell Biology, 2014 Tumour cell adhesion, motility, proteolytic activities and cell receptors have important roles in cancer invasion. These processes are involved from early development of melanoma within the epidermis, to tumour cell invasion of the underlying tissue until intravasation of lymphatic or blood vessels, and thereafter, dissemination into distant organs ...
Nives, Moro +2 more
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Clinical and Translational Medicine, 2021 Background Diabetic nephropathy (DN), one of the major complications of diabetes, is characterized by albuminuria, glomerulosclerosis, and progressive loss of renal function.
Viviana Casagrande +5 more
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Peptide-Based Inhibitors of ADAM and ADAMTS Metalloproteinases
Frontiers in Molecular Biosciences, 2021 ADAM and ADAMTS are two large metalloproteinase families involved in numerous physiological processes, such as shedding of cell-surface protein ectodomains and extra-cellular matrix remodelling.
Stefano Pluda +4 more
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Metalloproteinases and Metalloproteinase Inhibitors in Age-Related Diseases [PDF]
Current Pharmaceutical Design, 2014 Degradation of the extracellular matrix is an important feature of embryonic development, morphogenesis, angiogenesis, tissue repair and remodeling. It is precisely regulated under physiological conditions, but when dysregulated it becomes a cause of many diseases, including atherosclerosis, osteoarthritis, diabetic vascular complications, and ...
Simona, Gargiulo +3 more
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Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases [PDF]
Circulation Research, 2003 Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis, and in diseases such as atheroma, arthritis, cancer, and tissue ulceration.
Visse, R, Nagase, H
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Matrix Proteins and Proteinases Network in Human Cardiovascular Diseases Explored By Cytoscape [PDF]
Research Ideas and Outcomes, 2016 Matrix proteins and proteinases altered extracellular matrix that involves in various pathogenesis of cardiovascular diseases. Systematic review selected matrix metalloproteinase-7 (MMP7), a disintegrin and metalloproteinase-17 (ADAM17), type I collagen (
Robert Chen, Wei-hsuan Yu
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Toxins, 2022 Many venomous animals express toxins that show extraordinary levels of variation both within and among species. In snakes, most studies of venom variation focus on front-fanged species in the families Viperidae and Elapidae, even though rear-fanged ...
Peter A. Cerda +5 more
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