Results 31 to 40 of about 1,959,855 (381)
Neural regulation of cancer: from mechanobiology to inflammation. [PDF]
, 2016 Despite recent progress in cancer research, the exact nature of malignant transformation and its progression is still not fully understood. Particularly metastasis, which accounts for most cancer death, is a very complex process, and new treatment ...
Kim, Tae-Hyung +2 more
core +2 more sources
STAR Protocols, 2023 Summary: Organotypic brain cultures are short-term assays that phenotypically and functionally recapitulate brain metastatic cells in vivo. Here, we present a protocol to generate murine organotypic brain cultures for drug screening.
Lucía Zhu +4 more
doaj +1 more source
Neutrophils in cancer carcinogenesis and metastasis
Journal of Hematology & Oncology, 2021 In recent years, neutrophils have attracted increasing attention because of their cancer-promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic indicator for patients with cancer.
Shumin Xiong, Liaoliao Dong, Lin Cheng
semanticscholar +1 more source
Nature Reviews Cancer, 2019 Brain metastasis, which commonly arises in patients with lung cancer, breast cancer and melanoma, is associated with poor survival outcomes and poses distinct clinical challenges. The brain microenvironment, with its unique cell types, anatomical structures, metabolic constraints and immune environment, differs drastically from microenvironments of ...
Adrienne Boire +3 more
openaire +3 more sources
Nature Communications, 2019 Oncogenic exosomes can circulate in the blood, but their selective removal has not been possible. Here the authors show that aptamer-functionalised mesoporous silica nanoparticles can find to a specific population of circulating exosomes and eliminate ...
Xiaodong Xie +17 more
doaj +1 more source
Journal of Experimental & Clinical Cancer Research, 2019 Background Sorafenib is approved as a standard therapy for advanced hepatocellular carcinoma (HCC), but its clinical application is limited due to moderate therapeutic efficacy and high incidence of acquired resistance resulted from elevated levels of ...
Ning Zheng +8 more
doaj +1 more source
Using of Binominal Method for the Purpose of Determination of Confidence Intervals for Prediction of Invasive Ductal Breast Carcinoma Metastases [PDF]
, 2016 The study was performed using surgical and biopsy material based on histopathological study, which was conducted at the Chernivtsy Regional Clinical Oncology Centre.
Davydenko, I. (Igor) +1 more
core +2 more sources
International Journal of Molecular Sciences, 2023 Cancer metastasis is a common biological phenomenon observed in malignant tumors that can lead to death in affected individuals [...]
Masa-Aki Shibata, Kohei Taniguchi
openaire +2 more sources
Pericyte-expressed Tie2 controls angiogenesis and vessel maturation
Nature Communications, 2017 The angiopoietins regulate vascular maturation, angiogenesis and lymphangiogenesis via their Tie receptors that were long believed to be endothelium-specific.
Martin Teichert +13 more
doaj +1 more source
CD36-mediated metabolic crosstalk between tumor cells and macrophages affects liver metastasis
Nature Communications, 2022 Macrophage-mediated immune suppression contributes to poor outcome in liver metastasis. Here the authors show that CD36-expressing metastasis associated macrophages engulf tumor cell-derived extracellular vesicles enriched in long-chain fatty acids ...
Ping Yang +15 more
semanticscholar +1 more source