Results 21 to 30 of about 1,357,901 (303)
Systemic inflammation: Cancer's long-distance reach to maximize metastasis [PDF]
, 2015 While major improvements have been made in targeting primary tumor growth, metastasis and combating cancer spread remain an enigma. We recently identified a systemic inflammatory cascade involving IL17-producing γδ T cells and neutrophils that advance ...
Coffelt, Seth B., de Visser, Karin E.
core +1 more source
Nature Communications, 2019 Oncogenic exosomes can circulate in the blood, but their selective removal has not been possible. Here the authors show that aptamer-functionalised mesoporous silica nanoparticles can find to a specific population of circulating exosomes and eliminate ...
Xiaodong Xie +17 more
doaj +1 more source
The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation. [PDF]
, 2016 Nucleolar protein interacting with the FHA domain of pKi-67 (NIFK) is a Ki-67-interacting protein. However, its precise function in cancer remains largely uninvestigated.
Chang, Hong-Tai +17 more
core +2 more sources
Journal of Experimental & Clinical Cancer Research, 2019 Background Sorafenib is approved as a standard therapy for advanced hepatocellular carcinoma (HCC), but its clinical application is limited due to moderate therapeutic efficacy and high incidence of acquired resistance resulted from elevated levels of ...
Ning Zheng +8 more
doaj +1 more source
The Journal of Thoracic and Cardiovascular Surgery, 1993 Endobronchial metastases from nonpulmonary neoplasms are rare. Since 1971, we have treated 23 patients with endobronchial metastases, the findings for which form the basis of this article. Many types of primary tumors are capable of endobronchial metastases, although breast, colon, and renal carcinomas predominate.
R F, Heitmiller +3 more
openaire +2 more sources
STAR Protocols, 2023 Summary: Organotypic brain cultures are short-term assays that phenotypically and functionally recapitulate brain metastatic cells in vivo. Here, we present a protocol to generate murine organotypic brain cultures for drug screening.
Lucía Zhu +4 more
doaj +1 more source
Updated management of malignant biliary tract tumors: an illustrative review [PDF]
, 2016 The management of malignant biliary tumors (MBTs) is complex and requires a multidisciplinary approach. Guidelines and methods of staging for biliary tumors have recently been released by main international societies, altering the clinical and radiologic
Cannavale, Alessandro +6 more
core +1 more source
Pericyte-expressed Tie2 controls angiogenesis and vessel maturation
Nature Communications, 2017 The angiopoietins regulate vascular maturation, angiogenesis and lymphangiogenesis via their Tie receptors that were long believed to be endothelium-specific.
Martin Teichert +13 more
doaj +1 more source
Evaluating Modelling Approaches for Medical Image Annotations [PDF]
, 2010 Information system designers face many challenges with regards to selecting appropriate semantic technologies and deciding on a modeling approach for their system.
Bijan Parsia +2 more
core +5 more sources
Anti-S100A4 Antibody Suppresses Metastasis Formation by Blocking Stroma Cell Invasion
Neoplasia: An International Journal for Oncology Research, 2012 The small Ca-binding protein, S100A4, has a well-established metastasis-promoting activity. Moreover, its expression is tightly correlated with poor prognosis in patients with numerous types of cancer.
Jörg Klingelhöfer +6 more
doaj +1 more source