Results 21 to 30 of about 1,034,096 (317)

Bone metastasis pattern of cancer patients with bone metastasis but no visceral metastasis

Journal of Bone Oncology, 2019
Bone metastasis of cancer can be a result from systemic blood spreading or vertebral venous plexus spreading. Systemic blood pathway induced bone metastasis can happen in any bone in the body since the spreading is considered to be random. However, it remains unknown whether there is any pattern of vertebral venous plexus related bone metastasis.
Mingyu Zhu, Xin Liu, Yuan Qu, Silong Hu, Yingjian Zhang, Wentao Li, Xiaoyan Zhou, Huijuan Yang, Liangping Zhou, Qifeng Wang, Yifeng Hou, Yong Chen, Yanli Wang, Yaohui Wang, Zhongwu Lu, Zhiguo Luo, Xichun Hu   +16 more
openaire   +3 more sources

AKT2 Loss Impairs BRAF-Mutant Melanoma Metastasis

, 2023
Despite recent advances in treatment, melanoma remains the deadliest form of skin cancer due to its highly metastatic nature. Melanomas harboring oncogenic BRAFV600E mutations combined with PTEN loss exhibit unrestrained PI3K/AKT signaling and increased ...
Philip N. Tsichlis, Jodie Pietruska, Siobhan K. McRee, Philip W. Hinds, Abraham L. Bayer   +4 more
core   +1 more source

Breast cancer metastasis to the stomach [PDF]

, 2019
Aim: This study focuses on the stomach as an unusual but not rare site of metastasis of breast cancer. Methods: We performed a literature search on gastric metastasis from breast cancer searching for reviews from 2000 to 2018 and case reports from 2013
Rampini, Alessia, Antolino, Laura, Aurello, Paolo, Silvia Cardella, Paolo Aurello, Valabrega, Stefano, Alessia Rampini, Giovanni Ramacciato, Giuseppe Nigri, Cardella, Silvia, Francesco D'Angelo, Stefano Valabrega, D'Angelo, Francesco, Laura Antolino, Ramacciato, Giovanni, Nigri, Giuseppe   +15 more
core   +1 more source

[10]-gingerol is a potent inhibitor of breast cancer metastasis in vivo

, 2021
sem informação32322222315th International Biennial Congress of the Metastasis Research ...
Tomasin, Rebeka, Fernandes, Joao Batista, Pouliot, Normand, Ling, Phoebe, Vieira, Paulo Cezar, da Silva, James Almada, Moreno Martin, Ana Carolina B., de Araujo, Heloisa S. S., Cominetti, Marcia R.   +8 more
core   +1 more source

Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles

Nature Communications, 2019
Oncogenic exosomes can circulate in the blood, but their selective removal has not been possible. Here the authors show that aptamer-functionalised mesoporous silica nanoparticles can find to a specific population of circulating exosomes and eliminate ...
Xiaodong Xie, Huifang Nie, Yu Zhou, Shu Lian, Hao Mei, Yusheng Lu, Haiyan Dong, Fengqiao Li, Tao Li, Bifei Li, Jie Wang, Min Lin, Chaihung Wang, Jingwei Shao, Yu Gao, Jianming Chen, Fangwei Xie, Lee Jia   +17 more
doaj   +1 more source

Co-delivery of sorafenib and metapristone encapsulated by CXCR4-targeted PLGA-PEG nanoparticles overcomes hepatocellular carcinoma resistance to sorafenib

Journal of Experimental & Clinical Cancer Research, 2019
Background Sorafenib is approved as a standard therapy for advanced hepatocellular carcinoma (HCC), but its clinical application is limited due to moderate therapeutic efficacy and high incidence of acquired resistance resulted from elevated levels of ...
Ning Zheng, Weiqun Liu, Bifei Li, Huifang Nie, Jian Liu, Yunlong Cheng, Jichuang Wang, Haiyan Dong, Lee Jia   +8 more
doaj   +1 more source

Protocol to generate murine organotypic brain cultures for drug screening and evaluation of anti-metastatic efficacy

STAR Protocols, 2023
Summary: Organotypic brain cultures are short-term assays that phenotypically and functionally recapitulate brain metastatic cells in vivo. Here, we present a protocol to generate murine organotypic brain cultures for drug screening.
Lucía Zhu, Lauritz Miarka, Patricia Baena, María Perea-García, Manuel Valiente   +4 more
doaj   +1 more source

Hypoxia and Metastasis [PDF]

Clinical Cancer Research, 2007
In this issue of Clinical Cancer Research , Rofstad et al. ([1][1]) report on the significance of chronic (diffusion-limited) and acute (fluctuating or perfusion-limited) hypoxia in D-12 and R-18 human melanoma xenografts on the development of metastatic disease.
Naz, Chaudary, Richard P, Hill
openaire   +2 more sources

Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

Nature Communications, 2017
The angiopoietins regulate vascular maturation, angiogenesis and lymphangiogenesis via their Tie receptors that were long believed to be endothelium-specific.
Martin Teichert, Laura Milde, Annegret Holm, Laura Stanicek, Nicolas Gengenbacher, Soniya Savant, Tina Ruckdeschel, Zulfiyya Hasanov, Kshitij Srivastava, Junhao Hu, Stella Hertel, Arne Bartol, Katharina Schlereth, Hellmut G. Augustin   +13 more
doaj   +1 more source

Mechanisms of metastasis [PDF]

Breast Cancer Research, 2008
Metastasis is an enormously complex process that remains to be a major problem in the management of cancer. The fact that cancer patients might develop metastasis after years or even decades from diagnosis of the primary tumor makes the metastatic process even more complex.
Hunter, Kent W, Crawford, Nigel PS, Alsarraj, Jude   +2 more
openaire   +2 more sources