Results 31 to 40 of about 1,034,096 (317)
, 2022 INTRODUCTION: Pancreatic metastasis of lung cancer is rare, but the narrowing or obstruction of the biliary tract from pancreatic metastases limits the choice of antitumour agents.
Satoh, Hiroaki +9 more
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FOXO transcription factor family in cancer and metastasis [PDF]
, 2020 Forkhead box O (FOXO) transcription factors regulate diverse biological processes, affecting development, metabolism, stem cell maintenance and longevity. They have also been increasingly recognised as tumour suppressors through their ability to regulate
Lam, Eric, Jiramongkol, Yannasittha
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Anti-S100A4 Antibody Suppresses Metastasis Formation by Blocking Stroma Cell Invasion
Neoplasia: An International Journal for Oncology Research, 2012 The small Ca-binding protein, S100A4, has a well-established metastasis-promoting activity. Moreover, its expression is tightly correlated with poor prognosis in patients with numerous types of cancer.
Jörg Klingelhöfer +6 more
doaj +1 more source
, 2014 The purpose of this article is to outline the current approach to patients affected by metastasis to the spine and to present a clinical and surgical algorithm available for clinicians and for future research.
Casadei, Roberto +8 more
core +1 more source
Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition [PDF]
, 2013 Though clinicians can predict which patients are at risk for developing metastases, traditional therapies often prove ineffective and metastatic disease is the primary cause of cancer patient death; therefore, there is a need to develop anti-metastatic ...
Adam I. Marcus +39 more
core +1 more source
PKM2 Drives Hepatocellular Carcinoma Progression by Inducing Immunosuppressive Microenvironment
Frontiers in Immunology, 2020 Background and AimsPyruvate kinase M2 (PKM2) is an essential regulator of the Warburg effect, but its biological function promoting immune escape of hepatocellular carcinoma (HCC) is unclear.MethodsGEPIA web tool and immunohistochemistry (IHC) analysis ...
Tian-En Li +14 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Focal adhesion assembly and cell migration require myoferlin in PDAC cell lines
Scientific ReportsPancreatic ductal adenocarcinoma (PDAC) has a dire prognosis due to late diagnosis and ineffective treatments. Myoferlin, a transmembrane protein, is overexpressed in PDAC and correlates with poor patient survival, making it a potential therapeutic ...
Charlotte Gullo +11 more
doaj +1 more source
Targeting cellular senescence to combat cancer and ageing
Molecular Oncology, 2022 Senescence is a complex cellular process that is implicated in various physiological and pathological processes. It is characterized by a stable state of cell growth arrest and by a secretome of diverse pro‐inflammatory factors, chemokines and growth ...
Chen Wang, Xue Hao, Rugang Zhang
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source