Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity. [PDF]
PLoS ONE, 2012 Methamphetamine abuse continues to be a worldwide problem, damaging the individual user as well as society. Only minimal information exists on molecular changes in the brain that result from methamphetamine administered in patterns typical of human ...
Gurudutt Pendyala +2 more
doaj +1 more source
PLoS ONE, 2020 Methamphetamine use has increased over the past decade and the first use of methamphetamine is most often when women are of reproductive age. Methamphetamine accumulates in the liver; however, little is known about the effect of methamphetamine use on ...
Jia Yin Soo +6 more
doaj +1 more source
Effect of Methamphetamine on Spectral Binding, Ligand Docking and Metabolism of Anti-HIV Drugs with CYP3A4. [PDF]
PLoS ONE, 2016 Cytochrome P450 3A4 (CYP3A4) is the major drug metabolic enzyme, and is involved in the metabolism of antiretroviral drugs, especially protease inhibitors (PIs).
Anantha R Nookala +7 more
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A Review of Methods Used to Detect Methamphetamine from Indoor Air and Textiles in Confined Spaces
Toxics, 2022 Methamphetamine manufacture, use, and the resulting contamination is a significant issue that affects public health, the environment, and the economy.
Gemma L. Kerry +3 more
doaj +1 more source
Effects of methamphetamine on locomotor activity and thalamic gene expression in leptin-deficient obese mice [PDF]
, 2017 Leptin is an adipose-derived hormone that regulates energy balance. Leptin receptors are expressed in extrahypothalamic sites and several reports showed that leptin can influence feeding and locomotor behavior via direct actions on dopaminergic neurons ...
Bisagno, Veronica +3 more
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The effects of adolescent methamphetamine exposure
Frontiers in Neuroscience, 2015 Methamphetamine use among adolescents is a significant social and public health concern. Despite increased awareness of methamphetamine use among younger people, relatively little research has examined the effects of adolescent methamphetamine use ...
Jordan M Buck, Jessica Anne Siegel
doaj +1 more source
Decreased dopamine activity predicts relapse in methamphetamine abusers. [PDF]
, 2012 Studies in methamphetamine (METH) abusers showed that the decreases in brain dopamine (DA) function might recover with protracted detoxification. However, the extent to which striatal DA function in METH predicts recovery has not been evaluated.
Alia-Klein, N +11 more
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Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study. [PDF]
, 2014 IntroductionChildhood maltreatment, a well-known risk factor for the development of substance abuse disorders, is associated with functional and structural abnormalities in the adult brain, particularly in the limbic system.
Dean, Andy C +3 more
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Buprenorphine added on brief cognitive behavioral therapy for treatment of methamphetamine use disorder [PDF]
, 2018 Background: Methamphetamine (MA) use remains a major public health concern around the world. Recent findings suggest that buprenorphine may be helpful for cocaine use reduction. Moreover, animal studies described reduced dopamine peak effect following MA
Dean AJ +10 more
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High-risk Sexual Behavior is Associated with Post-Exposure Prophylaxis Non-adherence among Men who have Sex with Men Enrolled in a Combination Prevention Intervention. [PDF]
, 2013 Methamphetamine use among men who have sex with men (MSM) is associated with increased HIV prevalence, due to increased engagement in high-risk sexual behavior.
Fletcher, Jesse B +4 more
core +2 more sources