Results 21 to 30 of about 531,866 (340)

Dietary acid load and risk of cancer: new insights from a nationwide case-control study [PDF]

open access: yesWorld Cancer Research Journal, 2023
Objective: Dietary acid load can contribute to metabolic acidosis, which is closely linked to cancer development through inflammation and cell transformation mechanisms. However, limited epidemiologic evidence is still linking diet-dependent acid load and
A. Ronco   +4 more
doaj   +1 more source

Three-electron two-centred bonds and the stabilisation of cationic sulfur radicals [PDF]

open access: yes, 2014
Electronic communication in biological systems is fundamental to understanding protein signalling and electron hopping pathways. Frequently studied examples are cationic radical methionine and its functional derivatives.
Carbery, DR, Hendon, CH, Walsh, A
core   +1 more source

Supplementing Ruminally Protected Lysine, Methionine, or Combination Improved Milk Production in Transition Dairy Cows

open access: yesFrontiers in Veterinary Science, 2022
The objectives of this study were to evaluate the effects of dietary supplementation of ruminally protected lysine (RPL), or methionine (RPM), and their combination (RPML) on the production efficiency of transition cows.
Samy A. Elsaadawy   +6 more
doaj   +1 more source

The methionine salvage pathway in Bacillus subtilis [PDF]

open access: yes, 2002
BACKGROUND: Polyamine synthesis produces methylthioadenosine, which has to be disposed of. The cell recycles it into methionine through methylthioribose (MTR). Very little was known about MTR recycling for methionine salvage in Bacillus subtilis. RESULTS:
Danchin, Antoine, Sekowska, Agnieszka
core   +4 more sources

The Effect of Exogenous Protease in Broiler Diets on the Apparent Ileal Digestibility of Amino Acids and on Protease Activity in Jejunum

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016
The objective of this study was to evaluate the effect of a mono-component commercial serine protease supplement in broiler diets on apparent ileal amino acid digestibility and protease activity.
Vojtěch Rada   +3 more
doaj   +1 more source

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model. [PDF]

open access: yes, 2017
An excessive requirement for methionine termed methionine dependence, appears to be a general metabolic defect in cancer. We have previously shown that cancer-cell growth can be selectively arrested by methionine deprivation such as with recombinant ...
Chmielowski, Bartosz   +15 more
core   +2 more sources

Diel rhythmicity in amino acid uptake by Prochlorococcus [PDF]

open access: yes, 2008
The marine cyanobacterium Prochlorococcus, the most abundant phototrophic organism on Earth, numerically dominates the phytoplankton in nitrogen (N)-depleted oceanic gyres.
Burkill, Peter H.   +7 more
core   +3 more sources

Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia

open access: yesCells, 2019
Leukemias bearing mixed lineage leukemia (MLL) rearrangement (MLL-R) resulting in expression of oncogenic MLL fusion proteins (MLL-FPs) represent an especially aggressive disease subtype with the worst overall prognoses and chemotherapeutic response. MLL-
Aditya Barve   +7 more
doaj   +1 more source

EFFECT OF METHIONINE AND METHIONINE SULPHOXIMINE ON RAT BRAIN S‐ADENOSYL METHIONINE LEVELS [PDF]

open access: yesJournal of Neurochemistry, 1975
Abstract—Rat brain SAM levels were markedly increased after methionine administration, whereas the convulsant, L‐methionine‐dl‐sulphoximine (MSO), produced a 35 per cent decrease in whole brain content of S‐adenosyl‐L‐methionine (SAM). When methionine was given in combination with MSO, SAM levels were not decreased. Studies on the regional distribution
Schatz, Robert A., Sellinger, Otto Z.
openaire   +3 more sources

An infant with an extremely rare cobalamin disorder: Methionine synthase deficiency and importance of early diagnosis and treatment

open access: yesThe Turkish Journal of Pediatrics, 2019
Functional methionine synthase deficiency can be separated into two classes, cobalamin (Cbl) deficiency type E (CblE) and type G (CblG), which are the result of mutations that affect methionine synthase reductase or methionine synthase, respectively ...
Çiğdem Seher Kasapkara   +6 more
doaj   +1 more source

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