Three-electron two-centred bonds and the stabilisation of cationic sulfur radicals [PDF]
, 2014 Electronic communication in biological systems is fundamental to understanding protein signalling and electron hopping pathways. Frequently studied examples are cationic radical methionine and its functional derivatives.
Carbery, DR, Hendon, CH, Walsh, A
core +1 more source
Insights into the regulation of DMSP synthesis in the diatom Thalassiosira pseudonana through APR activity, proteomics and gene expression analyses on cells acclimating to changes in salinity, light and nitrogen [PDF]
, 2014 Despite the importance of dimethylsulphoniopropionate (DMSP) in the global sulphur cycle and climate regulation, the biological pathways underpinning its synthesis in marine phytoplankton remain poorly understood.
A Koprivova +61 more
core +13 more sources
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016 The objective of this study was to evaluate the effect of a mono-component commercial serine protease supplement in broiler diets on apparent ileal amino acid digestibility and protease activity.
Vojtěch Rada +3 more
doaj +1 more source
Diel rhythmicity in amino acid uptake by Prochlorococcus [PDF]
, 2008 The marine cyanobacterium Prochlorococcus, the most abundant phototrophic organism on Earth, numerically dominates the phytoplankton in nitrogen (N)-depleted oceanic gyres.
Burkill, Peter H. +7 more
core +3 more sources
Cells, 2019 Leukemias bearing mixed lineage leukemia (MLL) rearrangement (MLL-R) resulting in expression of oncogenic MLL fusion proteins (MLL-FPs) represent an especially aggressive disease subtype with the worst overall prognoses and chemotherapeutic response. MLL-
Aditya Barve +7 more
doaj +1 more source
EFFECT OF METHIONINE AND METHIONINE SULPHOXIMINE ON RAT BRAIN S‐ADENOSYL METHIONINE LEVELS [PDF]
Journal of Neurochemistry, 1975 Abstract—Rat brain SAM levels were markedly increased after methionine administration, whereas the convulsant, L‐methionine‐dl‐sulphoximine (MSO), produced a 35 per cent decrease in whole brain content of S‐adenosyl‐L‐methionine (SAM). When methionine was given in combination with MSO, SAM levels were not decreased. Studies on the regional distribution
Schatz, Robert A., Sellinger, Otto Z.
openaire +3 more sources
The Turkish Journal of Pediatrics, 2019 Functional methionine synthase deficiency can be separated into two classes, cobalamin (Cbl) deficiency type E (CblE) and type G (CblG), which are the result of mutations that affect methionine synthase reductase or methionine synthase, respectively ...
Çiğdem Seher Kasapkara +6 more
doaj +1 more source
Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model. [PDF]
, 2017 An excessive requirement for methionine termed methionine dependence, appears to be a general metabolic defect in cancer. We have previously shown that cancer-cell growth can be selectively arrested by methionine deprivation such as with recombinant ...
Chmielowski, Bartosz +15 more
core +2 more sources
Methionine Dependence of Cancer
Biomolecules, 2020 Tumorigenesis is accompanied by the reprogramming of cellular metabolism. The shift from oxidative phosphorylation to predominantly glycolytic pathways to support rapid growth is well known and is often referred to as the Warburg effect.
Peter Kaiser
doaj +1 more source
Developments in plant breeding for improved nutritional quality of soya beans I. Protein and amino acid content [PDF]
, 2000 Soya beans, like other legumes, contain low concentrations of the nutritionally essential sulphur amino acid, methionine. Cysteine, although not an essential amino acid because it can be synthesized from methionine, also influences the nutritional ...
Clarke, E, Wiseman, J
core +1 more source