Results 41 to 50 of about 531,866 (340)

The impact of general anesthesia on methionine metabolism during cardiopulmonary bypass

Вестник анестезиологии и реаниматологии, 2020
It has been found out that methylation of nucleic acids, proteins and low-molecular substrates is necessary to renew cellular structures, their restoration and cytoprotection.
Yu. S. Polushin, T. F. Subbotina, N. S. Molchan, A. A. Zhloba   +3 more
doaj   +1 more source

Genetic and molecular understanding for the development of methionine-rich maize: a holistic approach

Frontiers in Plant Science, 2023
Maize (Zea mays) is the most important coarse cereal utilized as a major energy source for animal feed and humans. However, maize grains are deficient in methionine, an essential amino acid required for proper growth and development. Synthetic methionine
Veena Devi, Bharat Bhushan, Mamta Gupta, Mehak Sethi, Charanjeet Kaur, Alla Singh, Vishal Singh, Ramesh Kumar, Sujay Rakshit, Dharam P. Chaudhary   +9 more
doaj   +1 more source

Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant - Implications for disease susceptibility to Creutzfeldt-Jakob disease [PDF]

, 2004
The human PrP gene (PRNP) has two common alleles that encode either methionine or valine at codon 129. This polymorphism modulates disease susceptibility and phenotype of human transmissible spongiform encyphalopathies, but the molecular mechanism by ...
Abdessamad Tahiri-Alaoui, Andrew C. Gill, Petra Disterer, William James, Prusiner, Weissmann, Will, Bruce, Hill, Prusiner, Prusiner, Collinge, Windl, Palmer, Brown, Baker, Cervenakova, Parchi, Hill, Collinge, Hauw, Goldfarb, Goldfarb, Dlouhy, Dermaut, Croes, Liemann, Riek, Alonso, Baskakov, Jackson, Baskakov, Gill, Lu, Lu, Landon, Safar, Bessen, Zahn, Riek, Nguyen, Tahiri-Alaoui, Santini, Wong, Wildegger, Matouschek, Vendruscolo, Kim, Fasman, Baskakov, Qin, Oesch, Conway, Sayer, Rhie, Schatzl, Mead   +56 more
core   +1 more source

Methionine sulfoxide reductase A is a stereospecific methionine oxidase [PDF]

Proceedings of the National Academy of Sciences, 2011
Methionine sulfoxide reductase A (MsrA) catalyzes the reduction of methionine sulfoxide to methionine and is specific for the S epimer of methionine sulfoxide. The enzyme participates in defense against oxidative stresses by reducing methionine sulfoxide residues in proteins back to methionine.
Jung Chae, Lim, Zheng, You, Geumsoo, Kim, Rodney L, Levine   +3 more
openaire   +2 more sources

Effect of Methionine Restriction on IGF-1 Gene Expression in Breast Muscle of Japanese Quail [PDF]

مجله بیوتکنولوژی کشاورزی, 2016
In the present study to investigate the effect of dietary methionine restriction on IGF-1 gene expression in breast muscle of  Japanese quail, 200 pieces of the birds were randomly divided into two different dietary groups containing recommended ...
Elaheh Rostam Zadeh, Masoud Asadi Fouzi, Ali Esmaeili Zadeh, Malek Hossein Asadi   +3 more
doaj   +1 more source

Methionine Partially Replaced by Methionyl-Methionine Dipeptide Improves Reproductive Performance over Methionine Alone in Methionine-Deficient Mice

Nutrients, 2018
Decreased protein breakdown in pregnant women results in lower concentration of methionine (Met) in plasma, causing pregnancy-related metabolic disturbance. Its dipeptide methionyl-methionine (Met-Met) may exert positive influence in fetal development.
Qiong Chen, Wenting Dai, Yalu Sun, Fengqi Zhao, Jianxin Liu, Hongyun Liu   +5 more
openaire   +2 more sources

Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of Mycobacterium tuberculosis through Nutrient Auxotrophy

mBio, 2018
Multidrug-resistant (MDR) tuberculosis, defined as tuberculosis resistant to the two first-line drugs isoniazid and rifampin, poses a serious problem for global tuberculosis control strategies.
Catherine Vilchèze, Jacqueline Copeland, Tracy L. Keiser, Torin Weisbrod, Jacqueline Washington, Paras Jain, Adel Malek, Brian Weinrick, William R. Jacobs   +8 more
doaj   +1 more source

Dietary soy and meat proteins induce distinct physiological and gene expression changes in rats [PDF]

, 2016
This study reports on a comprehensive comparison of the effects of soy and meat proteins given at the recommended level on physiological markers of metabolic syndrome and the hepatic transcriptome.
A Hagiwara, A Lass, A Shukla, A Subramanian, AM Uhe, B He, BB Albert, C Brandsch, C Chaveroux, CJ Andersen, CW Law, D Eberle, D El Khoury, D Gaidatzis, D Karolchik, D Merico, D Ord, D Tome, DW Gietzen, E Tornberg, G Fromentin, G Sarwar, H Sidransky, HX Yuan, J Cacho, J Schwarz, JI Lee, JL Jewell, JM Beasley, KK Carroll, L Abatangelo, L Noriega-Lopez, LE Matarese, M Friedman, M Shimobayashi, MD Robinson, MD Robinson, ME Ritchie, ML Orgeron, MS Kilberg, N Tachibana, PG Reeves, PM Leung, PM Pereira, R Bourgon, R Hoffenberg, R Hosomi, S Guo, S Madani, S Wen, SM Potter, SN Twigger, T Berry, TG Anthony, V Ranawana, W Gade, W Kang, Y Takahashi   +57 more
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Carboxy-Methylation of the Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Integrates Methionine Availability with Methionine Addicted Cancer Cell Proliferation

Biomolecules
Cancer cells exhibit a well-documented, yet poorly understood, dependence on exogenous methionine, despite retaining the capacity to convert homocysteine to methionine.
Anna Andronicos, Kiku C. Yoneda, Da-Wei Lin, Fiona V. Law, Hosung Bae, Ali Basirattalab, Nicholas A. Graham, Cholsoon Jang, Peter Kaiser   +8 more
doaj   +1 more source