Results 11 to 20 of about 359,969 (343)

Factors related to dosing frequency and route of administration in methotrexate intolerance among patients with rheumatoid arthritis: a cross-sectional study [PDF]

open access: yesTherapeutic Advances in Drug Safety
Background: Methotrexate is central to the management of rheumatoid arthritis (RA). However, its use is often limited by methotrexate intolerance. Objectives: This study aims to explore the association between alternative methotrexate dosing methods and ...
Haya M. Almalag   +9 more
doaj   +2 more sources

The effects of casticin and myricetin on liver damage induced by methotrexate in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2018
Objective(s): In this study, we evaluated the therapeutic effects of casticin and myricetin on liver  damage induced by methotrexate in rats.Materials and Methods: Thirty-six male rats were used for the study and divided into 6 groups: control ...
Fazile Nur Eki̇nci̇-Akdemi̇r   +6 more
doaj   +2 more sources

Retrospective evaluation and prediction of clearance and toxicity of high dose methotrexate in childhood acute lymphoblastic leukemia patients

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2021
To find the predictors of High Dose Methotrexate toxicities in childhood Acute Lymphoblastic Leukemia Patients. This study included 198 Childhood Acute Lymphoblastic Leukemia patients (303 infusions) who were treated with High Dose Methotrexate ...
Yuxia Shan   +6 more
doaj   +1 more source

Methotrexate hampers immunogenicity to BNT162b2 mRNA COVID-19 vaccine in immune-mediated inflammatory disease

open access: yesAnnals of the Rheumatic Diseases, 2021
Objective To investigate the humoral and cellular immune response to messenger RNA (mRNA) COVID-19 vaccines in patients with immune-mediated inflammatory diseases (IMIDs) on immunomodulatory treatment.
R. Haberman   +25 more
semanticscholar   +1 more source

Effect of methotrexate on neurobehavior and cholinesterase in chicks [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2023
This reading aimed to determine the therapeutic index of methotrexate (MTX) with a note on the consequence of methotrexate in chicks on neurobehavioral in addition to calculating the activity for cholinesterase in plasma and brain in chicks.
Maab A. Fadel   +2 more
doaj   +1 more source

Prevalence of methotrexate intolerance in juvenile idiopathic arthritis and possible risk factors: a tertiary center experience

open access: yesThe Journal of Pediatric Academy, 2022
Methotrexate that has a safe and inexpensive profile is a first choice of juvenile idiopathic arthritis treatment. Nevertheless, gastrointestinal symptoms are not serious but common side effects of methotrexate.
Zahide Ekici Tekin   +11 more
doaj   +1 more source

A Rare Case of Methotrexate Induced Pancreatitis in Ectopic Pregnancy

open access: yesThe Ewha Medical Journal, 2023
Ectopic pregnancy (EP) refers to blastocyst implantation outside the uterine endometrium. EP is major cause of maternal morbidity and mortality. Treatment options include surgery, medical therapy with methotrexate,
Jiwon Choi   +4 more
doaj   +1 more source

Harmine Has Nephroprotective Effect Against Methotrexate-Induced Injury in Mice via Inhibition of Oxidative Stress [PDF]

open access: yesResearch Journal of Pharmacognosy, 2021
Background and objectives: Despite clinical use, the efficacy of methotrexate is often limited by some adverse effects, mainly nephrotoxicity. The most common mechanism of methotrexate-induced kidney damages is oxidative stress.
Cyrus Jalili   +5 more
doaj   +1 more source

Sustained Remission and Outcomes with Abatacept plus Methotrexate Following Stepwise Dose De-escalation in Patients with Early Rheumatoid Arthritis

open access: yesRheumatology and Therapy, 2023
Introduction One target of rheumatoid arthritis (RA) treatment is to achieve early sustained remission; over the long term, patients in sustained remission have less structural joint damage and physical disability.
Paul Emery   +14 more
doaj   +1 more source

Overview of Dual-Acting Drug Methotrexate in Different Neurological Diseases, Autoimmune Pathologies and Cancers

open access: yesInternational Journal of Molecular Sciences, 2020
Methotrexate, a structural analogue of folic acid, is one of the most effective and extensively used drugs for treating many kinds of cancer or severe and resistant forms of autoimmune diseases.
P. Koźmiński   +3 more
semanticscholar   +1 more source

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