Results 1 to 10 of about 230,620 (99)
Methyl 2-methyl-3,5-dinitrobenzoate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 In the title compound, C(9)H(8)N(2)O(6), the methyl ester group is almost planar (r.m.s. deviation = 0.002 Å) and is oriented at a dihedral angle of 24.27 (16) ° with respect to the benzene ring. The nitro groups make dihedral angles of 4.2 (5) ° and 60.21 (11) ° with the benzene ring.
Rizwan Raza +4 more
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Acta Crystallographica Section E Structure Reports Online, 2008 The structure of the title compound, C(9)H(10)O(2), is related to that of 4-methyl-phenyl 4-methyl-benzoate and ethyl-ene di-4-methyl-benzoate showing similar bond parameters. The mol-ecule is planar, the dihedral angle between the aromatic ring and the -COOMe group being 0.95 (6)°. The cystal structure exhibits inter-molecular C-H⋯O contacts that link
Ulrich Flörke +2 more
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Acta Crystallographica Section E Structure Reports Online, 2008 THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: methyl 3-carboxy-3-hydr-oxy-3-(4-hydroxy-benz-yl)propanoate], C(12)H(14)O(6), is stabilized by inter-molecular O-H⋯O and C-H⋯O hydrogen bonds. The mol-ecules are arranged in layers, parallel to (001), which are inter-connected by the O-H⋯O hydrogen bonds.
Linglin Li +2 more
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DNA methylation age of human tissues and cell types
Genome Biology, 2013 It is not yet known whether DNA methylation levels can be used to accurately predict age across a broad spectrum of human tissues and cell types, nor whether the resulting age prediction is a biologically meaningful measure.
S. Horvath
semanticscholar +1 more source
Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
Bioinform., 2011 Summary: A combination of bisulfite treatment of DNA and high-throughput sequencing (BS-Seq) can capture a snapshot of a cell's epigenomic state by revealing its genome-wide cytosine methylation at single base resolution.
Felix Krueger, Simon R. Andrews
semanticscholar +1 more source
The role of m6A RNA methylation in cancer metabolism
Molecular Cancer, 2022 Metabolic reprogramming is one of the main characteristics of malignant tumors, which is due to the flexible changes of cell metabolism that can meet the needs of cell growth and maintain the homeostasis of tissue environments.
Yuanyuan An, Huayan Duan
semanticscholar +1 more source
EcoSal Plus, 2009 The DNA of Escherichia coli contains 19,120 6-methyladenines and 12,045 5-methylcytosines in addition to the four regular bases, and these are formed by the postreplicative action of three DNA methyltransferases. The majority of the methylated bases are formed by the Dam and Dcmmethyltransferases encoded by the
Marinus, Martin G. +1 more
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DNA methylation: a historical perspective.
Trends in Genetics, 2022 In 1925, 5-methylcytosine was first reported in bacteria. However, its biological importance was not intuitive for several decades. After this initial lag, the ubiquitous presence of this methylated base emerged across all domains of life and revealed a ...
Alexandra L. Mattei +2 more
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Acta Crystallographica Section E Structure Reports Online, 2009 THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND (SYSTEMATIC NAME: methyl 3,4,5-trihydroxy-benzoate), C(8)H(8)O(5), is composed of essentially planar mol-ecules [maximum departures from the mean carbon and oxygen skeleton plane of 0.0348 (10) Å]. The H atoms of the three hydroxyl groups, which function as hydrogen-bond donors and acceptors simultaneously ...
Silvina Pagola, Deborah Bebout
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Cell, 1999 The establishment of DNA methylation patterns requires de novo methylation that occurs predominantly during early development and gametogenesis in mice.
M. Okano, D. Bell, D. Haber, E. Li
semanticscholar +1 more source