Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα
Molecules, 2018 Isopsoralen (IPRN), one of the main effective ingredients in Psoralea corylifolia Linn, has a variety of biological effects, including antiosteoporotic effects.
Luna Ge +3 more
doaj +1 more source
Improvement of antitumor therapies based on vaccines and immune-checkpoint inhibitors by counteracting tumor-immunostimulationw [PDF]
, 2018 Immune-checkpoint inhibitors and antitumor vaccines may produce both tumor-inhibitory and tumor-stimulatory effects on growing tumors depending on the stage of tumor growth at which treatment is initiated.
Bustuoabad, Oscar David +8 more
core +2 more sources
OncoImmunology, 2018 Immune checkpoint blockade (ICB) is currently evaluated in patients with glioblastoma (GBM), based on encouraging clinical data in other cancers, and results from studies with the methylcholanthrene-induced GL261 mouse glioma.
Vassilis Genoud +7 more
doaj +1 more source
GFP transgenic medaka (Oryzias latipes) under the inducible cyp1a promoter provide a sensitive and convenient biological indicator for the presence of TCDD and other persistent organic chemicals. [PDF]
PLoS ONE, 2013 Persistent organic pollutants (POPs) are resistant to environmental degradation and can cause multitude of health problems. Cytochrome P450 1A (Cyp1a) is often up-regulated by POPs through the activation of aryl hydrocarbon receptor (AhR) pathway and is ...
Grace Hwee Boon Ng, Zhiyuan Gong
doaj +1 more source
Macrophage migration inhibition-activity after implantation of methylcholanthrene-induced sarcoma, Ehrlich ascites cancer or mouse ascites hepatoma-134 cancer cells in mice [PDF]
, 1976 Cells from methylcholanthrene-induced tumor (MC-tumor), Ehrlich ascites cancer or mouse ascites hepatoma (MH-134) were subcutaneously implanted in dorsal area of mice to examine the specific cell mediated immunity following implantation.
Yumura, Masahito
core +1 more source
Enhancement of Bio-Protective Functions by Low Dose/Dose-Rate Radiation
Dose-Response, 2006 Effects of low-dose-rate gamma-irradiation on the process of tumorigenesis were investigated in mice treated with a carcinogenic agent or irradiated with high dose X-rays at a high dose rate.
Kazuo Sakai +2 more
doaj +1 more source
Aristolochic Acid Affects Upper Tract Urothelial Cancer Behavior through the MAPK Pathway
Molecules, 2019 The prevalence of upper tract urothelial carcinoma (UTUC) in Taiwan is relatively higher than thatin Western countries. Aristolochic acid (AA), which is widely used in traditional Chinese herbology, is now recognized to be one of the carcinogens for UTUC.
I-Hsuan Chen +8 more
doaj +1 more source
Inhibitory effect of isologous regional lymphnode cells from the methylcholanthrene-induced sarcoma bearing mice on the tumor in vivo [PDF]
, 1970 MC-induced sarcomas produced under the skin on the back between scapulas of C3H mice were transplanted successively to the mice of the same strain.
Kashihara, Eiji
core +1 more source
The Role of Regulatory T Lymphocytes in Immune Control of MC-2 Fibrosarcoma
Acta Clinica Croatica, 2020 The role of T regulatory lymphocytes (Treg) particularly in cancer is well known. The goal of the present study was to determine the contribution of these lymphocytes in the regulation of anti-tumor immunity of CBA/HZgr mice against MC-2 fibrosarcoma ...
Tomislav Jukić +6 more
doaj +1 more source
Enhancement of experimental metastasis by tumor necrosis factor [PDF]
, 1993 The influence of endogenous and exogenous tumor necrosis factor (TNF) on metastasis was investigated in an experimental fibrosarcoma metastasis model.
Echtenacher, Bernd +5 more
core +2 more sources