Results 61 to 70 of about 17,936 (269)
iMetaOmics, Volume 2, Issue 3, September 2025.This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu +8 more
wiley +1 more source
Gastroenterology Research and Practice, 2018 Objective. The incidence of the upper gastrointestinal tumor has increased rapidly during recent decades. The relationship between local water pollution and the tumor is still not much clear, so this study was conducted to further investigate the local ...
Maliha Ghaffar +9 more
doaj +1 more source
Animal Models and Experimental Medicine, Volume 8, Issue 7, Page 1229-1252, July 2025.Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang +7 more
wiley +1 more source
Monocrotophos induces the expression and activity of xenobiotic metabolizing enzymes in pre-sensitized cultured human brain cells. [PDF]
PLoS ONE, 2014 The expression and metabolic profile of cytochrome P450s (CYPs) is largely missing in human brain due to non-availability of brain tissue. We attempted to address the issue by using human brain neuronal (SH-SY5Y) and glial (U373-MG) cells. The expression
Vinay K Tripathi +11 more
doaj +1 more source
Natural killer (NK) cells and their involvement in different types of cancer. Current status of clinical research [PDF]
, 2017 Natural killer cells are the main agents of innate immunity. Since 1970, various studies have repeatedly confirmed their involvement in decreasing local tumor growth and also decreasing the risk of metastasis, due to their cytotoxic effects and also ...
Moldovan, Adina D. +2 more
core +4 more sources
An endogenous aryl hydrocarbon receptor ligand induces preeclampsia‐like phenotypes in rats
The Journal of Physiology, Volume 603, Issue 2, Page 579-594, 15 January 2025.Abstract figure legend An endogenous AhR ligand (ITE) elevates maternal blood pressure and proteinuria in pregnant rats, and decreases uteroplacental blood flow and fetal and placental growth, all of which are hallmarks of preeclampsia. ITE also reduces vascular density, alters immune cell distribution and fetal sex‐specifically disturbs transcriptomes
Ying‐Jie Zhao +8 more
wiley +1 more source
Scientific Reports, 2020 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Chih-Cheng Chang +5 more
doaj +1 more source
Case Reports in Dentistry, Volume 2025, Issue 1, 2025.Osteosarcoma, the most common primary bone malignancy, rarely affects the jaw, representing only 6%–10% of cases. Jaw osteosarcoma typically occurs in individuals between the ages of 30 and 50 years and is uncommon in children. It often involves the mandible, especially in males, presenting with swelling, tooth mobility, and paraesthesia rather than ...
Jessica Simpson +3 more
wiley +1 more source
Journal of Pharmacological Sciences, 2009 Polycyclic aromatic hydrocarbons (PAHs) and dioxins are ubiquitous environmental pollutants and activate the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor.
Noriko Sanada +4 more
doaj +1 more source
In vitro studies on the inhibitory effect of lymph-node cells. I. Antitumor activity of regional lymph-node cells from methylcholanthrene-induced sarcoma bearing mice on the same primary culture sarcoma cells [PDF]
, 1970 As a step in the elucidation of immunity of human cancer from the standpoint of homotransplantation immunity, we conducted mixed cultures of regional lymph node cells from C3H mouse isotransplanted with methylcholanthrene-induced sarcoma (MC-tumor ...
Ohsugi, Masaki
core +1 more source