Results 171 to 180 of about 2,824 (198)
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Suppression ofl-Histidine Decarboxylase mRNA Expression by Methyleugenol
Biochemical and Biophysical Research Communications, 1997We investigated the effect of methyleugenol on anaphylaxis. Methyleugenol completely inhibited systemic anaphylaxis induced by compound 48/80 in mice. Methyleugenol also inhibited local anaphylaxis activated by anti-dinitrophenyl (DNP) IgE. Moreover, methyleugenol dose-dependently inhibited histamine release in mast cells activated by compound 48/80 or
B K, Shin, E H, Lee, H M, Kim
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Polyhedron, 2015
Two series of platinum(II) complexes of the formula [PtCl2(Meug)(Amine)] (1–6, Meug: methyleugenol) and [PtCl(Meug-1H)(Amine)] (7–13, Meug-1H: deprotonated methyleugenol) were synthesized and characterized by elemental analyses, IR,
Tran Thi Da +4 more
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Two series of platinum(II) complexes of the formula [PtCl2(Meug)(Amine)] (1–6, Meug: methyleugenol) and [PtCl(Meug-1H)(Amine)] (7–13, Meug-1H: deprotonated methyleugenol) were synthesized and characterized by elemental analyses, IR,
Tran Thi Da +4 more
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Safrole, eugenol and methyleugenol induce intrachromosomal recombination in yeast
Mutation Research/Genetic Toxicology, 1989Deletion of an integrated plasmid, a specific type of intrachromosomal recombination, was evaluated for inducibility with the phenylpropenes safrole, eugenol and methyleugenol in the yeast Saccharomyces cerevisiae. These phenylpropenes are found in food products, spices, pharmaceuticals and clove cigarettes. Safrole and eugenol are known carcinogens in
R H, Schiestl +4 more
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Antinociceptive effect of methyleugenol on formalin-induced hyperalgesia in mice
European Journal of Pharmacology, 2006The effects of methyleugenol, an essential oil isolated from Asiasari radix, on antinociception were examined using the formalin test in mice. Oral administration of 10 mg/kg methyleugenol significantly decreased the duration of licking and biting behavior in the second phase without affecting that of the first phase, as did diclofenac, a non-steroidal
Shingo, Yano +7 more
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Chemical Interaction of Protein Cysteine Residues with Reactive Metabolites of Methyleugenol
Chemical Research in Toxicology, 2017Methyleugenol (ME), an alkenylbenzene compound, is a natural ingredient of several herbs and is used as flavoring agent in foodstuffs and fragrance in cosmetics. The hepatotoxicity, cytotoxicity, and carcinogenesis of ME have been well documented, and metabolic activation has been suggested to involve in ME-induced toxicities.
Yukun Feng +5 more
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Determination of methyleugenol in rodent plasma by high-performance liquid chromatography
Journal of Chromatography B: Biomedical Sciences and Applications, 1995A method has been developed and validated for the analysis of methyleugenol, a volatile flavoring agent, in rodent plasma at concentrations from 0.050 to 10.0 micrograms/ml. The method involves the addition of acetonitrile to the plasma, removal of the protein precipitate, and analysis of the supernatant by reversed-phase (C18) HPLC using an ...
S W, Graves, S, Runyon
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Reduction of Safrole and Methyleugenol in Asari radix et rhizoma by Decoction
Forschende Komplementärmedizin / Research in Complementary Medicine, 2009Asari radix et rhizoma (Xixin, Manchurian Wildginger, Asarum spp) is a herbal drug commonly used as an ingredient in traditional Chinese medicine (TCM). Many species of Asarum contain safrole and methyleugenol as the main components of their volatile oils.
Chu, Chen +3 more
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Relaxant and Antispasmodic Actions of Methyleugenol on Guinea-Pig Isolated Ileum
Planta Medica, 2000The effects of methyleugenol (ME) on guinea-pig isolated ileum were studied. ME reversibly relaxed basal tonus (EC50 of 52.2 +/- 18.3 microM), an action unaltered by 0.5 microM tetrodotoxin or 0.5 mM hexamethonium, and relaxed the ileum pre-contracted with 60 mM KCl.
C C, Lima +5 more
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Electrophysiological Characterization of Methyleugenol: A Novel Agonist of GABA(A) Receptors
ACS Chemical Neuroscience, 2014Methyleugenol (ME) is a natural constituent isolated from many plant essential oils having multiple biological effects including anticonvulsant and anesthetic activities, although the underlying mechanisms remain unclear. Here, we identify ME as a novel agonist of ionotropic γ-aminobutyric acid (GABA) receptors.
Jing, Ding +9 more
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MbEOMT1 regulates methyleugenol biosynthesis in Melaleuca bracteata F. Muell
Tree PhysiologyAbstract Methyleugenol, a bioactive compound in the phenylpropene family, undergoes its final and crucial biosynthetic transformation when eugenol O-methyltransferase (EOMT) converts eugenol into methyleugenol. While Melaleuca bracteata F.
Chao, Yang +6 more
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