Results 101 to 110 of about 37,526 (188)

Advancing IBD Management: A Literature Review on the Role of Non‐Invasive Blood‐Based Biomarkers in Predicting and Assessing Pharmacodynamic Response to Treatment

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein   +8 more
wiley   +1 more source

New clustering module in BDPC bisulfite sequencing data presentation and compilation web application for DNA methylation analyses

open access: yesBioTechniques, 2009
The Bisulfite Sequencing Data Presentation and Compilation (BDPC) web interface for compilation and presentation of data from bisulfite sequencing DNA methylation studies has been improved by adding a new module.
Christian Rohde   +5 more
doaj   +1 more source

Epigenetic analyses suggest different pathways during pregnancy for development of type 1 diabetes in children with high versus low‐neutral human leukocyte antigen‐risk

open access: yesJournal of Internal Medicine, Volume 299, Issue 5, Page 570-586, May 2026.
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor   +6 more
wiley   +1 more source

The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]

open access: yes, 2020
Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core  

Changepoint detection in base-resolution methylome data reveals a robust signature of methylated domain landscape [PDF]

open access: yes, 2010
Lotta Dalenius Hahlin (2010) Mentorskap utifrån ett lösningsinriktat fokus. (Mentorship based on a solution-oriented focus. Skolutveckling och ledarskap, Lärarutbildningen halvfart/distans, Malmö HögskolaMånga elever hoppar av sin gymnasieutbildning pga.
Takao Yokoyama   +4 more
core   +1 more source

Epigenetic regulation of mycorrhizal symbioses: from plastic responses to transgenerational legacies

open access: yesNew Phytologist, Volume 250, Issue 3, Page 1438-1452, May 2026.
Summary Mycorrhizal symbioses represent one of the most widespread and ecologically significant plant–microbe interactions, shaping plant nutrition, stress resilience, and ecosystem functioning. Beyond their role in nutrient exchange and systemic defense, growing evidence suggests that these symbioses also influence plant plasticity within and across ...
Gerson Beltrán‐Torres   +9 more
wiley   +1 more source

A Highly Conserved SNARE‐Associated Protein Enhances Plant Immunity by Regulating Vesicle Trafficking

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3426-3440, May 2026.
ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk   +15 more
wiley   +1 more source

The Role of DNMT Methyltransferases and TET Dioxygenases in the Maintenance of the DNA Methylation Level

open access: yesBiomolecules
This review deals with the functional characteristics and biological roles of enzymes participating in DNA methylation and demethylation as key factors in epigenetic regulation of gene expression. The set of enzymes that carry out such processes in human
Anastasiia T. Davletgildeeva   +1 more
doaj   +1 more source

A temporal transcriptome and methylome in human embryonic stem cell-derived cardiomyocytes identifies novel regulators of early cardiac development

open access: yesEpigenetics, 2018
Stem cell-based cardiogenesis has become a powerful tool to enhance our understanding of cardiac development and test novel therapeutics for cardiovascular diseases.
Kai Fu   +6 more
doaj   +1 more source

Mild Photoperiod and Temperature Fluctuations Elicit Tissue‐Specific DNA Methylation Changes in Arabidopsis

open access: yes
Plant, Cell &Environment, EarlyView.
Ji Hoon Rhee   +4 more
wiley   +1 more source

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