Results 231 to 240 of about 365,379 (338)

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

TlyA is a 23S and 16S 2'-O-methylcytidine methyltransferase important for ribosome assembly in Bacillus subtilis. [PDF]

Nucleic Acids Res
Hibma JL, Munson LM, Jones JD, Nye TM, Koutmou KS, Simmons LA.   +5 more
europepmc   +1 more source

An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia

, 2018
Alok Swaroop, Jon A. Oyer, Christine Will, Xiaoxiao Huang, Wenbo Yu, Catalina Troche, Marinka Bulic, Benjamin H. Durham, Qiang Wen, John D. Crispino, Alexander D. MacKerell, Richard L. Bennett, Neil L. Kelleher, Jonathan D. Licht   +13 more
openalex   +2 more sources

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

A methyltransferase molecular switch unlocks <i>para</i>-quinone methide generation and oligomerization. [PDF]

Chem Sci
Ma C, Zhang Z, Wang W, Zhang F, Xie A, Zhang K, Ren X, Wang L, Che Q, Zhu T, Zhang J, Li D.   +11 more
europepmc   +1 more source

Methyltransferase Gene [PDF]

, 2020
openaire   +1 more source

Human opsin restoration by histone methylation using methyltransferase fusion protein SETD7-dCas9

Na Ly Tran, Yun Hee Kang, Hyun Yong Jeong, Yeo Jin Kim, Sang Chul Shin, Sang‐Heon Kim, Byoungho Park, Seung Ja Oh   +7 more
openalex   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Mechanistic Insights into SAM-Dependent Methyltransferases: A Review of Computational Approaches. [PDF]

Int J Mol Sci
Jędrzejewski M, Szeleszczuk Ł, Pisklak DM.   +2 more
europepmc   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source