Results 11 to 20 of about 124,916 (340)

DNA methylation and DNA methyltransferases [PDF]

, 2017
The prevailing views as to the form, function, and regulation of genomic methylation patterns have their origin many years in the past, at a time when the structure of the mammalian genome was only dimly perceived, when the number of protein-encoding ...
Bestor, Timothy H, Boulard, Mathieu, Edwards, John R, Yarychkivska, Olya   +3 more
core   +3 more sources

The Methylation Game: Epigenetic and Epitranscriptomic Dynamics of 5-Methylcytosine

Frontiers in Cell and Developmental Biology, 2022
DNA and RNA methylation dynamics have been linked to a variety of cellular processes such as development, differentiation, and the maintenance of genome integrity.
Adele Alagia, Monika Gullerova
doaj   +1 more source

Dual RNA-Seq of Flavobacterium psychrophilum and Its Outer Membrane Vesicles Distinguishes Genes Associated with Susceptibility to Bacterial Cold-Water Disease in Rainbow Trout (Oncorhynchus mykiss)

Pathogens, 2023
Flavobacterium psychrophilum (Fp), the causative agent of Bacterial Cold-Water disease in salmonids, causes substantial losses in aquaculture. Bacterial outer membrane vesicles (OMVs) contain several virulence factors, enzymes, toxins, and nucleic acids ...
Pratima Chapagain, Ali Ali, Mohamed Salem   +2 more
doaj   +1 more source

Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]

, 2019
Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing, Tian, Li, Wilson, Alexander E, Wu, Sheng   +3 more
core   +1 more source

The M. tuberculosis Rv1523 Methyltransferase Promotes Drug Resistance Through Methylation-Mediated Cell Wall Remodeling and Modulates Macrophages Immune Responses

Frontiers in Cellular and Infection Microbiology, 2021
The acquisition of antibiotics resistance is a major clinical challenge limiting the effective prevention and treatment of the deadliest human infectious disease tuberculosis.
Sabeeha Ali, Aquib Ehtram, Naresh Arora, P. Manjunath, P. Manjunath, Deodutta Roy, Nasreen Z. Ehtesham, Seyed E. Hasnain, Seyed E. Hasnain, Seyed E. Hasnain   +9 more
doaj   +1 more source

Gene Expression Profile of RNA N1-methyladenosine methyltransferases [PDF]

E3S Web of Conferences, 2020
N1-methyladenosine (m1A) is a kind of common and abundant methylation modification in eukaryotic mRNA and long-chain non-coding RNA. Nucleoside methyltransferase (MTase) of m1A is a diverse protein family, which is characterized by the presence of ...
Rao Mingzhu
doaj   +1 more source

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study [PDF]

, 2016
Aging is associated with alterations in the content and patterns of DNA methylation virtually throughout the entire human lifespan. Reasons for these variations are not well understood.
Bacalini, MARIA GIULIA, Bernhardt, Jürgen, Breusing, Nicolle, Bürkle, Alexander, Caiafa, Paola, Calabrese, Roberta, Capri, Miriam, Ciccarone, Fabio, Dollé, Martijn, Franceschi, Claudio, Gonos, Efstathios S, Grubeck Loebenstein, Beatrix, Grune, Tilman, Guastafierro, Tiziana, Hervonen, Antti, Hurme, Mikko, Jansen, Eugène, Koller, Bernhard, Malavolta, Marco, Moreno Villanueva, María, Reale, Anna, Schӧn, Christiane, Sikora, Ewa, Sindlinger, Thilo, Slagboom, P. Eline, Toussaint, Olivier, Zampieri, Michele   +26 more
core   +2 more sources

RmtC and RmtF 16S rRNA Methyltransferase in NDM-1–Producing Pseudomonas aeruginosa

Emerging Infectious Diseases, 2015
We investigated 16S rRNA methyltransferases in 38 blaNDM-1–positive Pseudomonas aeruginosa isolates and found RmtC in 3 isolates, 1 of which also harbored RmtF.
Mohibur Rahman, Kashi Nath Prasad, Ashutosh Pathak, Binod Kumar Pati, Avinash Singh, Cristina M. Ovejero, Saheem Ahmad, Bruno Gonzalez-Zorn   +7 more
doaj   +1 more source

ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing. [PDF]

, 2009
Constitutive heterochromatin in Arabidopsis thaliana is marked by repressive chromatin modifications, including DNA methylation, histone H3 dimethylation at Lys9 (H3K9me2) and monomethylation at Lys27 (H3K27me1).
Bernatavichute, Yana V, Cokus, Shawn, Feng, Suhua, Jacob, Yannick, Jacobsen, Steven E, Johnson, Lianna M, LeBlanc, Chantal A, Michaels, Scott D, Pellegrini, Matteo, Stroud, Hume   +9 more
core   +1 more source

DNMTs are required for delayed genome instability caused by radiation [PDF]

, 2012
This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited ...
Anderson, RM, Armstrong, CA, Iyer, P, Jones, GD, Narayanan, D, Sandhu, J, Singh, R, Talbot, CJ, Talbot, CJ, Tufarelli, C, Tufarelli, C   +10 more
core   +2 more sources