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Methylxanthines and breast cancer
International Journal of Cancer, 1988AbstractThe association between intake of methylaxnthines and risk of breast cancer was examined in this population‐based case‐control study conducted in Adelaide, South Australia. The study included 451 cases, and one control was matched to each case for age (to the nearest year).
T E, Rohan, A J, McMichael
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2010
Methylxanthines represent a unique class of drugs for the treatment of asthma. The methylxanthine theophylline has demonstrated efficacy in attenuating the three cardinal features of asthma - reversible airflow obstruction, airway hyperresponsiveness, and airway inflammation.
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Methylxanthines represent a unique class of drugs for the treatment of asthma. The methylxanthine theophylline has demonstrated efficacy in attenuating the three cardinal features of asthma - reversible airflow obstruction, airway hyperresponsiveness, and airway inflammation.
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2010
Caffeine is widely used to promote wakefulness and counteract fatigue induced by restriction of sleep, but also to counteract the effects of caffeine abstinence. Adenosine is a physiological molecule, which in the central nervous system acts predominantly as an inhibitory neuromodulator. Adenosine is also a sleep-promoting molecule.
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Caffeine is widely used to promote wakefulness and counteract fatigue induced by restriction of sleep, but also to counteract the effects of caffeine abstinence. Adenosine is a physiological molecule, which in the central nervous system acts predominantly as an inhibitory neuromodulator. Adenosine is also a sleep-promoting molecule.
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Methylxanthines and breast cancer
International Journal of Cancer, 1987AbstractWe investigated the relationship between methylxanthine consumption and breast cancer using data from a case‐control study which included 1,510 cases and 1,882 controls identified through a nation‐wide breast cancer screening program. There was no evidence of a positive association between methylxanthine consumption and risk of breast cancer ...
C, Schairer, L A, Brinton, R N, Hoover
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Methylxanthines in Apnea of Prematurity
Clinics in Perinatology, 1979Caffeine and theophylline are effective in the treatment of apnea in the newborn infant. Controlled studies of efficacy and comparative efficacy and studies of toxicity are visibly lacking. Both drugs exert their anti-apneic activity by stimulation of the respiratory center.
J V, Aranda, T, Turmen
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2010
Caffeine, an antagonist of adenosine A(1), A(2A) and A(2B) receptors, is known as an adjuvant analgesic in combination with non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen in humans. In preclinical studies, caffeine produces intrinsic antinociceptive effects in several rodent models, and augments the actions of NSAIDs and acetaminophen.
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Caffeine, an antagonist of adenosine A(1), A(2A) and A(2B) receptors, is known as an adjuvant analgesic in combination with non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen in humans. In preclinical studies, caffeine produces intrinsic antinociceptive effects in several rodent models, and augments the actions of NSAIDs and acetaminophen.
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2000
Abstract The closely related alkaloids caffeine (from Coffea arabica, but also present in tea, mate leaves, and cola nuts), theoph ylline (from Thea sinensis), and the less potent theobromine (from the seeds of Theobroma cacao) are widely used centrally acting stimulants.
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Abstract The closely related alkaloids caffeine (from Coffea arabica, but also present in tea, mate leaves, and cola nuts), theoph ylline (from Thea sinensis), and the less potent theobromine (from the seeds of Theobroma cacao) are widely used centrally acting stimulants.
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Methylxanthines and Inflammatory Cells
2010Both caffeine and theophylline have a variety of roles in regulating inflammatory responses. At pharmacologically relevant concentrations most of the effects of these commonly used methylxanthines are attributable to adenosine receptor blockade and histone deacetylase activation.
György, Haskó, Bruce, Cronstein
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Effects of Methylxanthines on the Fetus
Clinics in Perinatology, 1979The role of caffeine and other methylxanthines in prematurity, intrauterine growth retardation, and the respiratory distress syndrome is currently under investigation. Their pharmacokinetics are discussed together with their newly discovered beneficial role as possible inhibitors of premature labor and accelerators of fetal lung maturation.
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Verofylline, a methylxanthine bronchodilator, in asthma
Clinical Pharmacology and Therapeutics, 1984Verofylline, a long-acting polysubstituted methylxanthine bronchodilator, was taken orally by eight adult patients with asthma in a double-blind, crossover tolerance study. Peak expiratory flow, forced vital capacity, and its subdivisions were measured weekly 2, 4, and 6 hr after oral dosing with drug or placebo.
R C, Young +6 more
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