Results 141 to 150 of about 4,190 (187)
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Breast cancer and methylxanthine consumption
Cancer Causes and Control, 1992The well-publicized hypothesis that consumption of methylxanthines (e.g., caffeine, theobromine, and theophylline) may increase the risk of breast cancer in women has not been confirmed by most epidemiologic studies, which have reported no effect or only a small increase in breast cancer risk with caffeine.
C C, McLaughlin +5 more
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Analytical Methods For Quantitation of Methylxanthines
1997The methylxanthines can be determined in foods and biological systems by the chromatographic methods of TLC, GC, and HPLC. Ultraviolet spectroscopy following a separation procedure is also still used. More recently immunoassay methods have been developed. There is no single best method; the analyst must balance the features of each assay with the final
W J, Hurst, R A, Martin, S M, Tarka
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Methylxanthines as Adenosine Receptor Antagonists
Annals of Internal Medicine, 1985Excerpt To the editor: In the recent report concerning theophylline toxicity and the beta-adrenergic receptor system by Kearney and associates (1), theophylline and caffeine are referred to as "adr...
W J, Parsons, G L, Stiles
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Pharmacokinetics of diuretics and methylxanthines in the neonate
European Journal of Clinical Pharmacology, 1980The elimination of diuretics and methylxanthines is considerably slower in the neonate than in the adult. Dose guidelines, especially during long term maintenance, must be adjusted to account for this slower drug elimination. Pharmacokinetic studies and the requisite pharmacologic evaluation on diuretics such as hydrochlorothiazide, spironolactone ...
J V, Aranda, T, Turmen, B I, Sasyniuk
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Mechanism of respiratory effects of methylxanthines
Respiration Physiology, 1983Neural respiratory responses to theophylline, aminophylline and ethylenediamine were determined in paralyzed, vagotomized and glomectomized cats whose end-tidal PCO2 and brain temperature were kept constant. Intravenous theophylline and aminophylline similarly stimulated respiration, but ethylenediamine had no effect.
F L, Eldridge +3 more
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Doxofylline: The next generation methylxanthine
The Indian Journal of Pediatrics, 2008Methylxanthines are widely used in the treatment of asthma. Being one of the few drugs that can be administered orally, they are especially helpful in resource restricted settings. Theophylline, the commonly used methylxanthine drug is associated with a wide range of adverse effects accounting for the poor compliance and high drop-out rates.
Jhuma, Sankar, Rakesh, Lodha, S K, Kabra
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Caffeine and the Methylxanthines
1991Caffeine is the world’s most popular drug and is taken regularly in coffee, tea, cocoa, cola drinks, chocolate, and over-the-counter medicines.
Robin B. Kanarek, Robin Marks-Kaufman
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Inhibition of Pyridoxal Kinase by Methylxanthines
Enzyme, 2017In the presence of saturating concentrations of adenosine triphosphate (ATP) and rate-limiting amounts of pyridoxal, theophylline was found to inhibit sheep brain pyridoxal kinase (EC 2.7.1.35) competitively. The apparent inhibition constant (K(i)) of theophylline for pyridoxal kinase was determined as 8.7 μmol/l.
J B, Ubbink +3 more
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Food and Chemical Toxicology, 1988
This review provides a brief overview of known information on the human toxicity of theobromine and paraxanthine. Theobromine has some pharmacological effects, although these activities are considerably weaker than those of theophylline and/or caffeine, described in parts 1 and 2 of this series (Stavric, Fd Chem. Toxic.
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This review provides a brief overview of known information on the human toxicity of theobromine and paraxanthine. Theobromine has some pharmacological effects, although these activities are considerably weaker than those of theophylline and/or caffeine, described in parts 1 and 2 of this series (Stavric, Fd Chem. Toxic.
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Benefits of Polyphenols and Methylxanthines from Cocoa Beans on Dietary Metabolic Disorders
Foods, 2021Didier Bereau
exaly