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Current Issues in Molecular Biology, 2022 Theobromine is mainly found in plant foods, such as tea; the primary source of theobromine is the seeds of the Theobroma cacao tree. Theobromine is an alkaloid belonging to the methylxanthine class of drugs, and it is similar to theophylline and caffeine.
Sang Keun Ha, Hee-Weon Lee, In-Wook Choi
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PLoS ONE, 2014 PurposeTo assess the capacity of methylxanthines (caffeine, theophylline, theobromine and paraxanthine) to inhibit uric acid crystallization, and to evaluate their potential application in the treatment of uric acid nephrolithiasis.Materials and ...
Fèlix Grases Freixedas +2 more
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Psychopharmacology of Theobromine in Healthy Volunteers [PDF]
Psychopharmacology, 2013 Theobromine, a methylxanthine related to caffeine and present in high levels in cocoa, may contribute to the appeal of chocolate. However, current evidence for this is limited.We conducted a within-subjects placebo-controlled study of a wide range of oral theobromine doses (250, 500, and 1,000 mg) using an active control dose of caffeine (200 mg) in 80
Harriet de Wit +2 more
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Technologies, 2017 The aims of this study were to determine the proximate composition of cacao pod husk as well as the optimal conditions for extraction and purification of theobromine from cacao pod husk.
Van Tang Nguyen
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Theobromine and Parkinson’s disease [PDF]
PharmaciaThe defining neuropathological features of Parkinson’s disease (PD) include the progressive loss of dopaminergic neurons in the substantia nigra, together with the intraneuronal accumulation of α-synuclein in the form of Lewy bodies. Theobromine has been
Magdalena Kondeva-Burdina +2 more
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Development of a Novel Chocolate Utilizing Mushroom Fermentation and Associated Changes in Beneficial Components [PDF]
FoodsThis study investigated the secondary fermentation of cocoa beans using mushrooms to further improve the quality of beans. Cocoa beans were fermented using 42 species of basidiomycetes and ascomycetes. Mycelial growth was observed in 29 strains. When 75%
Shiori Fukuda +4 more
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Effect of a Home Bleaching Gel Containing Chitosan and Theobromine on Tooth Surface Roughness, Microhardness, and Colour Change [PDF]
GelsThis study aimed to evaluate the effect of experimental bleaching gels containing chitosan and theobromine and compare their performance in terms of tooth surface roughness, microhardness, and colour change with the bleaching gels BioWhiten ProHome and ...
Safıya Temizyurek +1 more
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Acta Stomatologica Croatica, 2021 Objective: Enamel remineralizing effects of theobromine have received much attention from the clinicians. The aim of this study was to investigate the caries preventive effect of theobromine containing toothpaste on children with early childhood caries ...
Muesser Ahu Durhan +4 more
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3-Methylxanthine production through biodegradation of theobromine by Aspergillus sydowii PT-2
BMC Microbiology, 2020 Background Methylxanthines, including caffeine, theobromine and theophylline, are natural and synthetic compounds in tea, which could be metabolized by certain kinds of bacteria and fungi.
Binxing Zhou +5 more
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One-way or two-way sweet link between theobromine and depression?
BMC Psychiatry, 2023 Theobromine is an abundant methylxanthine in cocoa/chocolate. A recent article in BMC Psychiatry concludes that theobromine consumption increases the risk of depression. In our opinion, it is difficult to make a correlation between dietary habits and the
Rafael Franco, Eva Martínez-Pinilla
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