Results 21 to 30 of about 4,190 (187)

Design, Synthesis and Assay of Novel Methylxanthine–Alkynylmethylamine Derivatives as Acetylcholinesterase Inhibitors

Molecules, 2022
Xanthine derivatives have been a great area of interest for the development of potent bioactive agents. Thirty-eight methylxanthine derivatives as acetylcholinesterase inhibitors (AChE) were designed and synthesized.
Danila V. Reshetnikov, Igor D. Ivanov, Dmitry S. Baev, Tatyana V. Rybalova, Evgenii S. Mozhaitsev, Sergey S. Patrushev, Valentin A. Vavilin, Tatyana G. Tolstikova, Elvira E. Shults   +8 more
doaj   +1 more source

Isolation, analysis and in vitro assessment of CYP3A4 inhibition by methylxanthines extracted from Pu-erh and Bancha tea leaves

Scientific Reports, 2019
Methylxanthines, purine alkaloids found in plants, are found in beverages (coffee, tea, cocoa) and foods (chocolate and other cocoa-containing foods) commonly consumed worldwide.
Kaloyan D. Georgiev, Maya Radeva-Ilieva, Stanila Stoeva, Iliya Zhelev   +3 more
doaj   +1 more source

Variação anual de metilxantinas totais em amostras de Ilex paraguariensis A. St. - Hil. (erva-mate) em Ijuí e Santa Maria, Estado do Rio Grande do Sul

Química Nova, 2006
Ilex paraguariensis is a native plant in Southern Brazil, whose leaves are utilized in beverages such as chimarrão and tererê. This study investigated variations of total methylxanthines in leaves from two Ilex populations collected at one-month ...
Alexandre Schubert, Francisco Fernandes Zanin, Danielle Fontana Pereira, Margareth Linde Athayde   +3 more
doaj   +1 more source

The risk of development of acute kidney injury in full-term infants with administration of methylxanthines

Patologìâ, 2021
Exploring new possibilities for the use of methylxanthines to prevent the development of acute kidney injury (AKI) in full-term infants with perinatal asphyxia.
L. S. Stryzhak, I. O. Anikin, O. V. Spakhi   +2 more
doaj   +1 more source

Optical aptasensor for in situ detection and quantification of methylxanthines in Ilex guayusa

ACI Avances en Ciencias e Ingenierías, 2022
The present work pursued the development of a system to detect and quantify methylxanthines in Ilex guayusa. The system, called IPMA (In situ Plant Metabolite Aptasensor), is based on an optical aptasensor that integrates a DNA complex and a porphyrin ...
Briggitte Alexandra León Intriago, Andre Cristina Montero Oleas, Diana Sofía Mollocana Yánez, Diana Joella Calderón Carvajal, María de Lourdes Torres Proaño   +4 more
doaj   +1 more source

Cafeína: revisão sobre métodos de análise Analytical methods for caffeine

Química Nova, 2007
Gravimetric and Bailey-Andrew methods are tedious and provide inflated results. Spectrofotometry is adequate for caffeine analysis but is lengthy. Gas chromatography also is applied to the caffeine analysis but derivatization is needed.
Carlos A. B. De Maria, Ricardo F. A. Moreira   +1 more
doaj   +1 more source

The effect of venous caffeine on the prevention of apnea of prematurity in the very preterm infants in the neonatal intensive care unit of Shahid Motahhari Hospital, Urmia, during a year

Journal of Advanced Pharmaceutical Technology & Research, 2019
Due to the importance of prevention of apnea of prematurity in the very preterm infants and the side effects of using methylxanthines in preterm infants, the present study was conducted and aimed at investigating the effects of prophylactic caffeine on ...
Zahra Fakoor, Ali Aghayar Makooie, Zahra Joudi, Rasool Gharaaghaji Asl   +3 more
doaj   +1 more source

RISKS AND BENEFITS OF METHYLXANTHINES THERAPY – CASE STUDY [PDF]

Romanian Journal of Pediatrics, 2014
Introduction. Apnea of prematurity (AOP), a developmental disorder of respiratory control present in approximately 80% of extremely low birth weight (ELBW) infants, that, if prolonged, may cause hypoxemia and low cardiac output, with subsequent ...
Mariana Boia, Delia Maria Nicoar, Aniko Maria Manea   +2 more
doaj   +1 more source

Exploring the Nutritional Composition and Bioactive Compounds in Different Cocoa Powders

Antioxidants, 2023
Cocoa, the main derivative of the seeds of Theobroma cacao L., has been recognized to have several effects on human health including antioxidant and neuro- and cardio-protective effects, among others.
María del Carmen Razola-Díaz, María José Aznar-Ramos, Vito Verardo, Sonia Melgar-Locatelli, Estela Castilla-Ortega, Celia Rodríguez-Pérez   +5 more
doaj   +1 more source

3D Bioprinted Breast Cancer‐Stroma Model with Tailored Migration‐Permissive Bioink Reveals Impact of Adipose‐Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics

Advanced Healthcare Materials, EarlyView.
A migration‐permissive bioink composed of methacrylated collagen type I and thiolated hyaluronic acid enables 3D bioprinting of breast cancer‐stroma models. Single‐cell tracking reveals that adipose stromal cells enhance tumor cell motility and stromal invasion, accompanied by collagen remodeling, and a shift in tumor cell morphology.
Sabrina Stecher, Joachim Schenk, Alessandro Cianciosi, Katherina Hemmen, David Böhringer, Franziska Dusi, Jessica Faber, Philipp Stahlhut, Benedikt Gantert, Emilie Rouenhoff, Annika Gmöhling, Tessa Lühmann, Jörg Teßmar, Jürgen Groll, Silvia Budday, Tomasz Jüngst, Ben Fabry, Katrin G. Heinze, Petra Bauer‐Kreisel, Torsten Blunk   +19 more
wiley   +1 more source