Results 151 to 160 of about 17,358 (223)

Propofol regulates METTL3-mediated PARP-1 m⁶A modification to promote Parthanatos to improve NSCLC chemotherapy resistance. [PDF]

Sci Rep
Ling Q, Liu K, Wen J, Liu J, Chen Y.
europepmc   +1 more source

The mechanism by which methylase METTL3 affects intramuscular fat deposition. [PDF]

Poult Sci
Yu B, Li K, Li X, Zhang J.
europepmc   +1 more source

METTL3 plays multiple functions in biological processes.

American journal of cancer research
N6-methyladenosine (m6A) is the most common internal modification of mRNAs in higher eukaryotic. This process is performed by methyltransferase. Methyltransferase-like 3 (METTL3) is the best known m6A methyltransferase that functions in the reversible epi-transcriptome modulation of m6A modification.
Shuiping, Liu, Lvjia, Zhuo, Jianjun, Wang, Qin, Zhang, Qiujie, Li, Guohua, Li, Lili, Yan, Ting, Jin, Ting, Pan, Xinbing, Sui, Qun, Lv, Tian, Xie   +11 more
openaire   +1 more source

Recent advances in m6A RNA modification in hepatocellular carcinoma: from mechanisms to therapeutic potential. [PDF]

Front Mol Biosci
Shi Q, Liu Y, Xuan M, Fu L, Lou N, Lv C, Xue C.   +6 more
europepmc   +1 more source

The asymmetrical ROS-METTL3-ESR1 axis in paraspinal muscle progenitor cells determines the progression of adolescent idiopathic scoliosis. [PDF]

Exp Mol Med
Li B, Kuati A, Sui W, Cai J, Zhang T, Deng Y, Yang J, Lin X, Shao X.   +8 more
europepmc   +1 more source

Manipulation therapy alleviates neuropathic pain <i>via</i> the SOCS1 m⁶A epigenetic loop. [PDF]

Korean J Pain
Wu L, Wang X, Yang P, Wang X, Zheng Y, Tang Y, Zheng H, Ning P, Tang H.   +8 more
europepmc   +1 more source

Polystyrene Nanoplastics induced placental toxicology by activating Keap1-mediated ferroptosis via METTL3-dependent m6A methylation. [PDF]

Cell Biol Toxicol
Chen Y, Liu Y, Zhang M, Li S, Yan Y, Yin C.   +5 more
europepmc   +1 more source

Pre-clinical anti-tumor activity and preliminary safety of METTL3 inhibitors STM2457 and UZH1a in neuroblastoma. [PDF]

Transl Cancer Res
Lin T, Chen X, Huang H, Zhang J, Xu Y, Lin J.   +5 more
europepmc   +1 more source

N6-methyladenosine-modified miR-873 promotes receptor-interacting protein kinase 3-mediated necroptosis after intracerebral hemorrhage in mice and HT22 cells. [PDF]

Neuroreport
Wang J, Wang S, Wu X, Lu B, Huang J, Yu D, Zhao S, Chu Z, Yao Y, Xu Y.   +9 more
europepmc   +1 more source

Epitranscriptomic Regulation of Platinum Resistance via the METTL3-ADAM23 Axis in Ovarian Cancer. [PDF]

Cells
Kim U, Li J, Matei D, Huang H.
europepmc   +1 more source