Identification of TMEM2 as a SOX4 Transcriptional Target Involved in Breast Cancer Metastasis [PDF]
, 2015 The transcription factor SRY (sex determining region Y)-box 4 (SOX4) regulates embryonic development and has been shown to drive the progression and metastasis of multiple solid cancer types.
Lee, Hyeseung
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Correction: METTL3 accelerates staphylococcal protein A (SpA)-induced osteomyelitis progression by regulating m6A methylation-modified miR-320a. [PDF]
J Orthop Surg ResGao D +6 more
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Enhancing sensitivity of triple-negative breast cancer to DNA damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 [PDF]
Among the different types of breast cancer, triple-negative breast cancer (TNBC) displays the most unfavourable prognosis and high risk of recurrence. Conventional chemotherapy and DNA damaging agents are the main treatment for this cancer. However, this
CESARO, BIANCA
core
METTL3-Regulated m6A Epitranscriptome Plasticity in Pathological Angiogenesis [PDF]
Molecular Therapy, 2020 openaire +2 more sources
RNA Binding by the m6A Methyltransferases METTL16 and METTL3
BiologyMethyltransferases are a wide-ranging, yet well-conserved, class of molecules that have been found to modify a wide variety of substrates. Interest in RNA methylation has surged in recent years with the identification of the major eukaryotic mRNA m6A methyltransferase METTL3.
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The METTL3 inhibitor STM2457 suppresses gastric cancer progression by modulating m6A RNA modification. [PDF]
PLoS OneSun H +13 more
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N6-methyladenosine modification of NEU1 mediated by METTL3 exacerbates angiotensin II-induced atrial fibrillation. [PDF]
Cell Adh MigrZhang Z, Luo Y, Zou Q, Mo Z.
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