Results 121 to 130 of about 5,468 (165)
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An improved chemical ionization assay for mevalonic acid
Biological Mass Spectrometry, 1990The determination of mevalonic acid by gas chromatography/mass spectrometry (GC/MS) is complicated by poor extractability and multiple product formation. Reliable quantification down to physiological levels was achieved by isolating mevalonic acid by liquid partition chromatography and quantifying the underivatized lactone by means of ammonia chemical ...
G F, Hoffmann, L, Sweetman
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Comparative Biosynthesis of Mevalonic Acid by Mycoplasma
Journal of Bacteriology, 1965Smith, Paul F. (University of South Dakota, Vermillion), and C. V. Henrikson . Comparative biosynthesis of mevalonic acid by Mycoplasma . J. Bacteriol. 89: 146–153. 1965.—Three representative Mycoplasma, M. laidlawii strain B,
P F, SMITH, C V, HENRIKSON
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Planta, 2002
Isopentenyl diphosphate (IPP) is produced via two independent biosynthetic pathways in higher plants: the mevalonate (MVA) pathway in the cytoplasm and the non-mevalonate 2-C-methyl- D-erythritol-4-phosphate (MEP) pathway in plastids. It has been previously suggested that IPP or IPP-derived products can be exchanged between the cytoplasm and plastids ...
Noriko, Nagata +3 more
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Isopentenyl diphosphate (IPP) is produced via two independent biosynthetic pathways in higher plants: the mevalonate (MVA) pathway in the cytoplasm and the non-mevalonate 2-C-methyl- D-erythritol-4-phosphate (MEP) pathway in plastids. It has been previously suggested that IPP or IPP-derived products can be exchanged between the cytoplasm and plastids ...
Noriko, Nagata +3 more
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Biochimica et Biophysica Acta, 1962
Abstract The requirement of three species of lactobacillus for acetate and its replacement by mevalonic acid was investigated. It was found that, in the presence of 1% glucose, Lactobacillus acidophilus had a requirement for sodium acetate which could be replaced by 1/8000 times its concentration of mevalonic acid, but when the glucose ...
K J, THORNE, E, KODICEK
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Abstract The requirement of three species of lactobacillus for acetate and its replacement by mevalonic acid was investigated. It was found that, in the presence of 1% glucose, Lactobacillus acidophilus had a requirement for sodium acetate which could be replaced by 1/8000 times its concentration of mevalonic acid, but when the glucose ...
K J, THORNE, E, KODICEK
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Synthesis of 5S-5-[3H1]mevalonic acid
Journal of the Chemical Society D: Chemical Communications, 1970The three methylene groups of mevalonic acid permit six modes of stereospecific labelling by introduction of an isotopic hydrogen atom; five of these are already known, and synthesis of the sixth, 5S-5-[3H1]-mevalonic acid, is now reported.
J. W. Cornforth, F. P. Ross
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Biochimica et Biophysica Acta, 1962
Abstract In an investigation of the synthesis of the unsaponifiable lipids of Lactobacillus casei from mevalonic acid, it was shown that although no preferential order of synthesis of the components could be detected there was a turnover of the principal one with a simultaneous increase in the others.
K J, THORNE, E, KODICEK
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Abstract In an investigation of the synthesis of the unsaponifiable lipids of Lactobacillus casei from mevalonic acid, it was shown that although no preferential order of synthesis of the components could be detected there was a turnover of the principal one with a simultaneous increase in the others.
K J, THORNE, E, KODICEK
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Metabolism of mevalonic acid to phosphorylated derivatives in Chlorella
Biochemical and Biophysical Research Communications, 1977Summary The incorporation of mevalonic acid into phosphorylated derivatives was studied for the first time in Chlorophyceae algae. Cell-free extracts and cell suspensions of Chlorella fusca were able to phosphorylate mevalonic acid. The total mevalonate phosphorylation showed a clear maximum at pH 8.2.
A, Linares +2 more
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Enzymic Synthesis of Mevalonic Acid in Plants
1989The biosynthesis of mevalonic acid (“MVA”), starting from acetyl-CoA (“Ac-CoA”), requires the action of three enzymes: a) acetoacetyl-CoA thiolase (“AACT”, EC 2.3.1.9), b) 3-hydroxy-3-methylglutaryl-CoA synthase (“HMGS”, EC 4.1.3.5), and c) HMG-CoA reductase (“HMGR”, EC 1.1.1.34).
Bach, Thomas J., Weber, Thomas
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Terpene Formation in Pine from Mevalonic Acid
Nature, 1958RECENT studies have demonstrated that mevalonic acid is a key intermediate in the biosynthesis of animal sterols1. Studies of the origin of triterpenes and carotenoids in soya bean and fungi indicate that these compounds may also be formed from acetate through mevalonic acid2.
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