Results 11 to 20 of about 134,376 (245)
MHC class II expression in human basophils: induction and lack of functional significance. [PDF]
PLoS ONE, 2013 The antigen-presenting abilities of basophils and their role in initiating a Th2 phenotype is a topic of current controversy. We aimed to determine whether human basophils can be induced to express MHC Class II and act as antigen presenting cells for T ...
Astrid L Voskamp +4 more
doaj +1 more source
Present Yourself! By MHC Class I and MHC Class II Molecules [PDF]
Trends in Immunology, 2016 Since the discovery of MHC molecules, it has taken 40 years to arrive at a coherent picture of how MHC class I and MHC class II molecules really work. This is a story of the proteases and MHC-like chaperones that support the MHC class I and II molecules in presenting peptides to the immune system.
Rock, K.L., Reits, E., Neefjes, J.
openaire +3 more sources
Toxins, 2012 Anthrax Lethal Toxin consists of Protective Antigen (PA) and Lethal Factor (LF), and current vaccination strategies focus on eliciting antibodies to PA. In human vaccination, the response to PA can vary greatly, and the response is often directed toward ...
Judith A. James +8 more
doaj +1 more source
Towards universal structure-based prediction of class II MHC epitopes for diverse allotypes. [PDF]
PLoS ONE, 2010 The binding of peptide fragments of antigens to class II MHC proteins is a crucial step in initiating a helper T cell immune response. The discovery of these peptide epitopes is important for understanding the normal immune response and its misregulation
Andrew J Bordner
doaj +1 more source
BMC Genomics, 2008 Background In teleosts, the Major Histocompatibility Complex (MHC) class I and class II molecules reside on different linkage groups as opposed to tetrapods and shark, where the class I and class II genes reside in one genomic region. Several teleost MHC
Bakke Hege G +3 more
doaj +1 more source
The Journal of Poultry Science, 2005 The aim of this study was to determine whether the expressions of MHC class I and II in the ovarian follicles change with follicular growth and aging of birds. Theca layer of white follicles (WF), the largest and the third largest preovulatory follicles
Kalpana Subedi, Yukinori Yoshimura
doaj +1 more source
MHC Class II epitope predictive algorithms [PDF]
Immunology, 2010 SummaryMajor histocompatibility complex class II (MHC‐II) molecules sample peptides from the extracellular space, allowing the immune system to detect the presence of foreign microbes from this compartment. To be able to predict the immune response to given pathogens, a number of methods have been developed to predict peptide–MHC binding.
Nielsen, Morten +3 more
openaire +3 more sources
Cell Transplantation, 2002 The limited availability of human embryonic tissue for dopamine cell transplants in Parkinson's patients has led to an increased interest in using xenogeneic donor tissue.
Lone M. Veng +7 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 Major histocompatibility complex (MHC) class I and II are crucial for the adaptive immune system because they are involved in peptide presentation to T cells.
Synne Arstad Bjørnestad +5 more
doaj +1 more source
Biology, 2016 Major histocompatibility complex (MHC) molecules are key players in initiating immune responses towards invading pathogens. Both MHC class I and class II genes are present in teleosts, and, using phylogenetic clustering, sequences from both classes have ...
Unni Grimholt
doaj +1 more source