PLoS ONE, 2014 The human gammaherpesviruses establish life-long infections that are associated with the development of lymphomas and neoplasms, especially in immunocompromised individuals. T cells play a crucial role in the control of gammaherpesvirus infection through
Brandon Cieniewicz +2 more
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Regulation of Host and Viral RNA Expression during Gammaherpesvirus Infection [PDF]
, 2015 Gammaherpesviruses are oncogenic viruses that establish latent infection and can periodically reactivate. Replication, reactivation from latency and gammaherpesvirus-mediated pathology are regulated by viral and host factors.
Canny, Susan Priscilla
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Pathogens, 2017 RTA, the viral Replication and Transcription Activator, is essential for rhadinovirus lytic gene expression upon de novo infection and reactivation from latency.
Alexis L. Santana +8 more
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Investigation of LANA: a human virus tumor gene [PDF]
, 2019 Tese de mestrado, Ciências Biofarmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2019Kaposi’s sarcoma-associated herpesvirus (KSHV) is one of the seven recognized human tumor viruses.
Sousa, Anita Marisa Pinto
core
Regulation of B cell response to respiratory viruses [PDF]
, 2011 Viruses replicating in the respiratory tract (RT) triggers a wide- range of cytokines and chemokines that have antiviral and pro-inflammatory features, instigating an efficient virus- specific B and T cell response that aids in virus- clearance.
Sundararajan, Aarthi
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Sequential early-life viral infections modulate the microbiota and adaptive immune responses to systemic and mucosal vaccination [PDF]
Increasing evidence points to the microbial exposome as a critical factor in maturing and shaping the host immune system, thereby influencing responses to immune challenges such as infections or vaccines.
Aggarwal, Somya +13 more
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Regulation of Epithelial Turnover by Host-Virome Interactions [PDF]
, 2016 The host immune system must constantly function to maintain chronic commensal and pathogenic organisms in check. These organisms include the virome, which is the viral component of the microbiome.
Sun, Lulu
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Tegument Protein BNRF1 Regulation of Epstein-Barr Virus Genome Chromatinization During Early Infection [PDF]
, 2014 Epstein-Barr virus (EBV) is a ubiquitously prevalent human herpesvirus whose persistent latent infection is associated with many lymphomas. The prevalence of this virus can be attributed to its ability to establish a persistent latent infection in host ...
Tsai, Kevin
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A Role for the Hypoxia-Inducible Factor 1 Alpha in Murine Gammaherpesvirus 68 (MHV68) Lytic Replication and Reactivation from Latency [PDF]
The hypoxia inducible factor 1 alpha (HIF1α) protein and the hypoxic microenvironment are critical for infection and pathogenesis by the oncogenic gammaherpesviruses (γHV) such as Kaposi\u27 Sarcoma-associated Herpes Virus (KSHV) and Epstein-Barr virus ...
López-Rodríguez, Darlah Michelle
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The role of innate immune response in controlling murine gammaherpesvirus 68 acute infection in vivo [PDF]
, 2022 Zargari Orozaki, Razieh
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