Inter-Strain Epigenomic Profiling Reveals a Candidate IAP Master Copy in C3H Mice
Viruses, 2020 Insertions of endogenous retroviruses cause a significant fraction of mutations in inbred mice but not all strains are equally susceptible. Notably, most new Intracisternal A particle (IAP) ERV mutagenic insertions have occurred in C3H mice. We show here
Rita Rebollo +7 more
doaj +2 more sources
Inbred Strain-Specific Response to Biglycan Deficiency in the Cortical Bone of C57BL6/129 and C3H/He Mice [PDF]
Journal of Bone and Mineral Research, 2008 Inbred strain‐specific differences in mice exist in bone cross‐sectional geometry, mechanical properties, and indices of bone formation. Inbred strain‐specific responses to external stimuli also exist, but the role of background strain in response to ...
Joseph M. Wallace +3 more
semanticscholar +3 more sources
Immunological and nonimmunological control of severity of Trypanosoma musculi infections in C3H and C57BL/6 inbred mice [PDF]
Infection and Immunity, 1989 Studies concerned with the mechanisms responsible for relative resistance or susceptibility of strains of inbred mice to Trypanosoma musculi infections are presented. Treatment with 400 rads of ionizing radiation, silica dust, or trypan blue (reticuloendothelial blocking agents) rendered C3H mice unable to control the initial maximum level of parasite ...
J. W. Albright, J. F. Albright
semanticscholar +3 more sources
Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains. [PDF]
Drug and Alcohol Dependence, 2008 Drug abuse is common among adolescents and young adults. Although the consequences of intoxication are known, sequelae of drugs emerging on campuses and in clubs nationwide are not. We previously demonstrated that ketamine exposure results in lasting physiological abnormalities in mice.
C. Majewski-Tiedeken +2 more
semanticscholar +3 more sources
Quantitative Trait Loci for Femoral and Lumbar Vertebral Bone Mineral Density in C57BL/6J and C3H/HeJ Inbred Strains of Mice [PDF]
Journal of Bone and Mineral Research, 2001 Abstract Significant differences in vertebral (9%) and femoral (50%) adult bone mineral density (BMD) between the C57BL/6J (B6) and C3H/HeJ (C3H) inbred strains of mice have been subjected to genetic analyses for quantitative trait loci (QTL).
W. Beamer +7 more
semanticscholar +5 more sources
Association of pulmonary lymphocytes with radiation-induced lung disease in a mouse model [PDF]
Radiation OncologyBackground Specific congenic mice derived from inbred C3H/HeJ mice, which present early onset pneumonitis, and C57BL/6J mice manifesting later onset pneumonitis with pulmonary fibrosis, vary in time to respiratory distress from these responses following ...
Laetitia Sabatier +3 more
doaj +2 more sources
A lung cancer mouse model system based on an inbred C3H strain: Ultrasound imaging, pathological analysis, and proteomic biomarker identification [PDF]
Veterinary WorldBackground and Aim: Lung cancer remains a leading cause of global mortality, necessitating robust animal models for research into its mechanisms and therapeutic options.
Ulayatul Kustiati +6 more
doaj +2 more sources
Molecular vision, 2015 Purpose Recent advances in optogenetics and gene therapy have led to promising new treatment strategies for blindness caused by retinal photoreceptor loss.
Michiel van Wyk +2 more
semanticscholar +4 more sources
The establishment of the C3H inbred strain of mice for the study of spontaneous carcinoma of the mammary gland [PDF]
CA: A Cancer Journal for Clinicians, 1935 become interested in the use of inbred strains of mice for the study of sponta neous neoplasia. This advance has been encouraging to geneticists, who have in sisted, with great reason, that intrinsic or genetic factors do play a very important role in ...
L. Strong
semanticscholar +4 more sources
Differential Effects of Bone Structural and Material Properties on Bone Competence in C57BL/6 and C3H/He Inbred Strains of Mice [PDF]
Calcified Tissue International, 2008 Calcified Tissue International, 83 (1)
R. Voide, G. H. van Lenthe, R. Müller
semanticscholar +6 more sources