Results 1 to 10 of about 54,165 (230)

Differential Effects of Bone Structural and Material Properties on Bone Competence in C57BL/6 and C3H/He Inbred Strains of Mice [PDF]

Calcified Tissue International, 2018
The femoral neck is a relevant and sensitive site for studying the degree of osteopenia. Engineering principles predict that bone structural parameters, like cross-sectional geometry, are important determinants of bone mechanical parameters.
Müller, Ralph, van Lenthe, G., Voide, Romain   +2 more
core   +7 more sources

Inter-Strain Epigenomic Profiling Reveals a Candidate IAP Master Copy in C3H Mice

Viruses, 2020
Insertions of endogenous retroviruses cause a significant fraction of mutations in inbred mice but not all strains are equally susceptible. Notably, most new Intracisternal A particle (IAP) ERV mutagenic insertions have occurred in C3H mice. We show here
Rita Rebollo, Mariana Galvão-Ferrarini, Liane Gagnier, Ying Zhang, Ardian Ferraj, Christine R. Beck, Matthew C. Lorincz, Dixie L. Mager   +7 more
doaj   +2 more sources

Association of pulmonary lymphocytes with radiation-induced lung disease in a mouse model [PDF]

Radiation Oncology
Background Specific congenic mice derived from inbred C3H/HeJ mice, which present early onset pneumonitis, and C57BL/6J mice manifesting later onset pneumonitis with pulmonary fibrosis, vary in time to respiratory distress from these responses following ...
Laetitia Sabatier, Aimée-Lee Luco, Mitchell Wiebe, Christina K. Haston   +3 more
doaj   +2 more sources

A lung cancer mouse model system based on an inbred C3H strain: Ultrasound imaging, pathological analysis, and proteomic biomarker identification [PDF]

Veterinary World
Background and Aim: Lung cancer remains a leading cause of global mortality, necessitating robust animal models for research into its mechanisms and therapeutic options.
Ulayatul Kustiati, Wahyu Tri Widayati, Dwi Liliek Kusindarta, Dwi Aris Agung Nugrahaningsih, Dinda Aliffia, Wilda Bunga Tina Sanjaya, Hevi Wihadmadyatami   +6 more
doaj   +2 more sources

Mouse models for pseudoxanthoma elasticum: genetic and dietary modulation of the ectopic mineralization phenotypes. [PDF]

PLoS ONE, 2014
Pseudoxanthoma elasticum (PXE), a heritable ectopic mineralization disorder, is caused by mutations in the ABCC6 gene. Null mice (Abcc6(-/-) ) recapitulate the genetic, histopathologic and ultrastructural features of PXE, and they demonstrate early and ...
Qiaoli Li, Haitao Guo, David W Chou, Annerose Berndt, John P Sundberg, Jouni Uitto   +5 more
doaj   +5 more sources

Caracterização biológica de clones das cepas Y, CL e MR de Trypanosoma cruzi em camundongos C3H isogênicos Biological characterization of Trypanosoma cruzi clones from Y, CL and MR strains in C3H inbred mice

Memorias do Instituto Oswaldo Cruz, 1988
Dez clones isolados das cepas Y, CL e MR foram caracterizados segundo infectividade das culturas, curvas de parasitemia, polimorfismo e mortalidade em camundongos C3H isogênicos.
S. Marques de Araújo, E. Chiari
doaj   +2 more sources

Proteome analysis of high affinity mouse saliva proteins to hydroxyapatite

Heliyon, 2022
Caries sensitivity varies between the two strains of inbred mice, BALB/cA has high sensitivity and C3H/HeN has low sensitivity. One potential reason seems to be a difference in pellicle-forming saliva protein composition.
Keijiro Ohshima, Tomoko Ohshima, Karen Meyer, Eisuke Takai, Shunsuke Yoshizawa, Kentaro Shiraki, Nobuko Maeda   +6 more
doaj   +1 more source

Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice. [PDF]

, 2016
Background: P. aeruginosa is one of the top three causes of opportunistic human bacterial infections. The remarkable variability in the clinical outcomes of this infection is thought to be associated with genetic predisposition.
A Bragonzi, A Bragonzi, A Bragonzi, A Corken, A Darvasi, Alessandra Bragonzi, C Cigana, C Morissette, C Morissette, CC Elbers, Cristina Cigana, CS Haley, D Nguyen, DL Demeo, DM Menge, E Amiel, EE Smith, F Iraqi, F Iraqi, FA Iraqi, FA Iraqi, Fuad A. Iraqi, GA Churchill, GR Cutting, GS Cooke, H Shinohara, I Bianconi, Ida De Fino, J Dupuis, JB Lyczak, JE Pennington, JM Collaco, K Sapru, K Tremblay, Karl W. Broman, KW Broman, L Guillot, LD Hazlett, Lorenza Spagnuolo, M Hernandez-Valladares, M Munoz, M Simone De, M Tam, M Verdrengh, MA Jong de, Maura De Simone, ML Drumm, N Lorè, NI Lore, Nicola Ivan Lorè, R Mashima, R Mashima, R Williams, S Aerts, S Gruenheid, S Worgall, SL Cheng, SL Gellatly, SM Vidal, TT Wu, V DeRose, Y Moreau, Y Zhan   +62 more
core   +3 more sources

Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice

Laboratory Animal Research, 2020
To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and C4 mRNA, as well as C3 protein and C3 convertase activity in the serum and ...
Ji Won Park, Ji Eun Kim, Mi Ju Kang, Hyeon Jun Choi, Su Ji Bae, Dae Youn Hwang   +5 more
doaj   +1 more source

Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice [PDF]

Journal of Genetics, 2010
Three-point bending technology has been widely used in the measurement of bone strength. Quantitative trait loci (QTLs) for bone strength have been identified using mouse femurs. In this study, we investigate the use of mouse tibiae in identification of QTLs that regulate bone strength. Mouse tibiae were from a F(2) population derived from C57BL/6J (B6)
Jiao, F, Chiu, H, Jiao, Y, de, Rijk W, Li, X, Eckstein, E C, Beamer, W G, Gu, W   +7 more
openaire   +2 more sources