Results 11 to 20 of about 54,165 (230)

Inbred Strain-Specific Response to Biglycan Deficiency in the Cortical Bone of C57BL6/129 and C3H/He Mice [PDF]

Journal of Bone and Mineral Research, 2009
Abstract Inbred strain-specific differences in mice exist in bone cross-sectional geometry, mechanical properties, and indices of bone formation. Inbred strain-specific responses to external stimuli also exist, but the role of background strain in response to genetic deletion is not fully understood.
Wallace, Joseph M., Golcuk, Kurtulus, Morris, Michael D., Kohn, David H.   +3 more
openaire   +3 more sources

Immunological and nonimmunological control of severity of Trypanosoma musculi infections in C3H and C57BL/6 inbred mice [PDF]

Infection and Immunity, 1989
Studies concerned with the mechanisms responsible for relative resistance or susceptibility of strains of inbred mice to Trypanosoma musculi infections are presented. Treatment with 400 rads of ionizing radiation, silica dust, or trypan blue (reticuloendothelial blocking agents) rendered C3H mice unable to control the initial maximum level of parasite ...
J W, Albright, J F, Albright
openaire   +3 more sources

Quantitative Trait Loci for Femoral and Lumbar Vertebral Bone Mineral Density in C57BL/6J and C3H/HeJ Inbred Strains of Mice [PDF]

Journal of Bone and Mineral Research, 2001
Abstract Significant differences in vertebral (9%) and femoral (50%) adult bone mineral density (BMD) between the C57BL/6J (B6) and C3H/HeJ (C3H) inbred strains of mice have been subjected to genetic analyses for quantitative trait loci (QTL).
Beamer, W G, Shultz, K L, Donahue, L R, Churchill, G A, Sen, S, Wergedal, J R, Baylink, D J, Rosen, C J   +7 more
semanticscholar   +5 more sources

Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains [PDF]

Drug and Alcohol Dependence, 2008
Drug abuse is common among adolescents and young adults. Although the consequences of intoxication are known, sequelae of drugs emerging on campuses and in clubs nationwide are not. We previously demonstrated that ketamine exposure results in lasting physiological abnormalities in mice.
Chalon R, Majewski-Tiedeken, Cara R, Rabin, Steven J, Siegel   +2 more
openaire   +3 more sources

Trabecular and Cortical Bone of Growing C3H Mice Is Highly Responsive to the Removal of Weightbearing.

PLoS ONE, 2016
Genetic make-up strongly influences the skeleton's susceptibility to the loss of weight bearing with some inbred mouse strains experiencing great amounts of bone loss while others lose bone at much smaller rates. At young adulthood, female inbred C3H/HeJ
Bing Li, Jeyantt Srinivas Sankaran, Stefan Judex   +2 more
doaj   +2 more sources

Variable phenotypic expressivity in inbred retinal degeneration mouse lines: A comparative study of C3H/HeOu and FVB/N rd1 mice

Molecular vision, 2015
Recent advances in optogenetics and gene therapy have led to promising new treatment strategies for blindness caused by retinal photoreceptor loss. Preclinical studies often rely on the retinal degeneration 1 (rd1 or Pde6b(rd1)) retinitis pigmentosa (RP) mouse model. The rd1 founder mutation is present in more than 100 actively used mouse lines.
van Wyk, Michiel, Schneider, Sabine, Kleinlogel, Sonja   +2 more
openaire   +4 more sources

Comparative effects of vasectomy surgery and buprenorphine treatment on faecal corticosterone concentrations and behaviour assessed by manual and automated analysis methods in C57 and C3H mice. [PDF]

PLoS ONE, 2013
Establishing effective cage-side pain assessment methods is essential if post-surgical pain is to be controlled effectively in laboratory animals. Changes to overall activity levels are the most common methods of assessment, but may not be the most ...
Sian Wright-Williams, Paul A Flecknell, Johnny V Roughan   +2 more
doaj   +2 more sources

Cocaine locomotor activation, sensitization and place preference in six inbred strains of mice

Behavioral and Brain Functions, 2011
Background The expanding set of genomics tools available for inbred mouse strains has renewed interest in phenotyping larger sets of strains. The present study aims to explore phenotypic variability among six commonly-used inbred mouse strains to both ...
Grabowski-Boase Laura, Eisener-Dorman Amy F, Tarantino Lisa M   +2 more
doaj   +2 more sources

Bone Loss and TLR4 Signals Contribute Independently to B Lineage Aging. [PDF]

Aging Cell
The prevailing view is that the age‐related decline of B lymphopoiesis is due to increased inhibitory signals in the marrow environment. Our data show that the loss of salutary ones, such as those from bone, primarily drives the loss of B cell progenitors with age.
Baker E, Montecino-Rodriguez E, Xu S, Tetradis S, Rouault A, Estrada OI, Dorshkind K.   +6 more
europepmc   +2 more sources

A DIFFERENCE IN SKELETAL TYPE BETWEEN RECIPROCAL HYBRIDS OF TWO INBRED STRAINS OF MICE (C57 BLK AND C3H) [PDF]

Genetics, 1951
E L, Green, W L, Russell
openaire   +3 more sources