Frequent DNA Polymorphisms Exist in Inbred CBA/J and C3H/HeN Mice
Genomics, 1996 Although occasional DNA polymorphisms have been observed in inbred mice, CBA/J and C3H/HeN mice have two microsatellite alleles at over 1/3 of microsatellite loci tested. Since DNA polymorphisms were not detected in DBA/2J, C57BL/6J, and BALB/cJ, the frequency of microsatellite polymorphisms appears to be strain specific.
B, Yuan +4 more
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Effects of atherogenic diet consumption on lipoproteins in mouse strains C57BL/6 and C3H
Journal of Lipid Research, 1991 Inbred mouse strains C57BL/6J (B6) (susceptible) and C3H/HeJ (C3H) (resistant) differ in atherosclerosis susceptibility due to a single gene, Ath-1. Plasma lipoproteins from female mice fed chow or an atherogenic diet displayed strain differences in ...
BY Ishida +4 more
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Unraveling genetic modifiers in the gria4 mouse model of absence epilepsy. [PDF]
PLoS Genetics, 2014 Absence epilepsy (AE) is a common type of genetic generalized epilepsy (GGE), particularly in children. AE and GGE are complex genetic diseases with few causal variants identified to date.
Wayne N Frankel +4 more
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Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]
, 1975 Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan +36 more
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Bone Reports, 2018 The long term skeletal effects of antenatal exposure to teratogen 5-deoxy-2′-cytidine (5-AZA) were studied using two inbred strains, C3H/HeJ (C3H, with inherently stronger bones) and C57Bl/6J (C57, with weaker bones). We previously reported that in-utero
Deepak Kumar Khajuria +7 more
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Inbred Strain-Specific Effects of Exercise in Wild Type and Biglycan Deficient Mice [PDF]
, 2010 Biglycan (bgn)-deficient mice (KO) have defective osteoblasts which lead to changes in the amount and quality of bone. Altered tissue strength in C57BL6/129 (B6;129) KO mice, a property which is independent of tissue quantity, suggests that deficiencies ...
Darling, Eric M. +4 more
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Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping
Frontiers in Genetics, 2019 The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman +4 more
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Immobilization induced osteopenia is strain specific in mice
Bone Reports, 2015 Immobilization causes rapid and massive bone loss. By comparing Botulinum Toxin A (BTX)-induced bone loss in mouse strains with different genetic backgrounds we investigated whether the genetic background had an influence on the severity of the ...
Andreas Lodberg +5 more
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Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replication. [PDF]
PLoS ONE, 2014 Pseudomonas aeruginosa is a common cause of healthcare-associated infections including pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of P.
Maura De Simone +7 more
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Lysed Enterococcus faecalis FK-23 (LFK) Suppressing Allergic Responses in Mouse Models
Allergology International, 2005 Recently, several clinical trials have been published to discuss the possibility of probiotic supplementation, especially some products of lactic acid bacteria such as Lactobacillus and Bifidobacterium strains, in prevention and treatment of allergic ...
Takashi Shimada +6 more
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