Results 61 to 70 of about 54,165 (230)
A Mouse Immunogenicity Model for the Evaluation of Meningococcal Conjugate Vaccines
Frontiers in Immunology, 2022 The identification of an appropriate animal model for use in the development of meningococcal vaccines has been a challenge as humans are the only natural host for Neisseria meningitidis.
Arun B. Arunachalam +2 more
doaj +1 more source
Chromatin variation associated with liver metabolism is mediated by transposable elements [PDF]
, 2016 Additional file 1: Supplementary methods. Figure S1. Phenotypic diversity in different inbred strains. Figure S2. Chromatin variability across inbred strains of mice. Figure S3. Association between chromatin variation and SNPs. Figure S4.
Aldons J. Lusis +7 more
core +2 more sources
Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source
Sex differences in the physiological response to acute anterior cruciate ligament overuse
The Journal of Physiology, Volume 604, Issue 1, Page 297-316, 1 January 2026.Abstract figure legend With equivalent in vivo fatigue loading of the anterior cruciate ligament (ACL), females accumulate more tissue damage and mount a slower reparative response than males, when the applied loads between sexes are equivalent. By contrast, males accumulate less tissue damage and mount a robust reparative response that includes ...
Stephen H. Schlecht +5 more
wiley +1 more source
Vaccines, 2019 The type of IgG subclasses induced by vaccination is an important determinant of vaccine efficacy because the IgG subclasses vary in their biological function.
Yung-Yi C. Mosley +2 more
doaj +1 more source
Stress of Strains: Inbred Mice in Liver Research.
Gene Expression, 2018 Inbred mice are the most popular animals used for in vivo liver research. These mice are genetically defined, readily available, less expensive to maintain than larger animals, and enjoy a broad array of commercial reagents for scientific ...
A. Rogers
semanticscholar +1 more source
Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males. [PDF]
PLoS Genetics, 2014 Segregation of chromosomes during the first meiotic division relies on crossovers established during prophase. Although crossovers are strictly regulated so that at least one occurs per chromosome, individual variation in crossover levels is not uncommon.
Brian Baier +3 more
doaj +1 more source
Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons [PDF]
, 2004 Mcl1 is a Bcl2-related antiapoptotic protein originally isolated from human myeloid leukemia cells. Unlike Bcl2, expression has not been reported in CNS neurons.
Burgess, D. L. +8 more
core +1 more source
Physiological Reports, Volume 13, Issue 24, December 2025.Abstract The main transcriptional coactivator of the WNT pathway, β‐catenin, is a well‐established regulator of adipogenesis and fat expansion, but our knowledge of how other members of the catenin family participate in adipogenesis remains incomplete. Previous studies have elucidated a role for the β‐catenin homolog, plakoglobin, in the regulation of ...
Frederic Abou Azar +6 more
wiley +1 more source
Journal of Lipid Research, 2001 Interindividual and interstrain variations in cholesterol absorptionefficiency occur in humans and animals. We investigated physiological biliaryand small intestinal factors that might determine variations in cholesterolabsorption efficiency among inbred
David Q-H. Wang +2 more
doaj +1 more source