Results 71 to 80 of about 15,270 (172)

Thirty Mouse Strain Survey of Voluntary Physical Activity and Energy Expenditure: Influence of Strain, Sex and Day–Night Variation

Frontiers in Neuroscience, 2020
We measured indirect calorimetry and activity parameters, VO2 and VCO2 to extract respiratory exchange ratio (RER) and energy expenditure in both sexes of 30 inbred mouse strains of 6 genetic families at 9–13 weeks during one photophase and the ...
Christine König, Anne-Christine Plank, Alexander Kapp, Ivanna K. Timotius, Ivanna K. Timotius, Stephan von Hörsten, Katharina Zimmermann   +6 more
doaj   +1 more source

Variations in the germinal center response revealed by genetically diverse mouse strains

Immunology &Cell Biology, Volume 102, Issue 10, Page 935-948, November‐December 2024.
In this study, we investigated the impact of genetic variation on the germinal center response. Using a panel of genetically divergent strains, we uncover an important impact of genetics on the number, size and cellular composition of germinal centers, both at steady state and after immune challenge.
Anne‐Marie Aubin, Daria Vdovenko, Roxanne Collin, Lois Balmer, Lise Coderre, Grant Morahan, Félix Lombard‐Vadnais, Sylvie Lesage   +7 more
wiley   +1 more source

A PCR method to detect the mouse major histocompatibility complex H2-Ld gene that confers resistance to Toxoplasma encephalitis

BioTechniques
In laboratory mice, the H2-Ld gene confers resistance to encephalitis upon infection with Toxoplasma gondii, a foodborne parasite capable of infecting all endotherm animals tested. H2-Ld is carried by inbred strains with major histocompatibility complex (
Natalie E. Bicknell, Aseel Abuzaid, Glenn A. McConkey, Steven J. Clapcote   +3 more
doaj   +1 more source

Mouse models for pseudoxanthoma elasticum: genetic and dietary modulation of the ectopic mineralization phenotypes.

PLoS ONE, 2014
Pseudoxanthoma elasticum (PXE), a heritable ectopic mineralization disorder, is caused by mutations in the ABCC6 gene. Null mice (Abcc6(-/-) ) recapitulate the genetic, histopathologic and ultrastructural features of PXE, and they demonstrate early and ...
Qiaoli Li, Haitao Guo, David W Chou, Annerose Berndt, John P Sundberg, Jouni Uitto   +5 more
doaj   +1 more source

Comparison of Adult Hippocampal Neurogenesis and Susceptibility to Treadmill Exercise in Nine Mouse Strains

Neural Plasticity, 2017
The genetic background of mice has various influences on the efficacy of physical exercise, as well as adult neurogenesis in the hippocampus. In this study, we investigated the basal level of hippocampal neurogenesis, as well as the effects of treadmill ...
Jong Whi Kim, Sung Min Nam, Dae Young Yoo, Hyo Young Jung, Il Yong Kim, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoon   +7 more
doaj   +1 more source

Mouse genetic approaches applied to the normal tissue radiation response

Frontiers in Oncology, 2012
The varying responses of inbred mouse models to radiation exposure present a unique opportunity to dissect the genetic basis of radiation sensitivity and tissue injury.
Christina Kathleen Haston
doaj   +1 more source

Identification of novel molecular candidates for fatty liver in the hyperlipidemic mouse model, HcB19

Journal of Lipid Research, 2004
The inbred HcB19 mouse strain expresses a truncated form of thioredoxin interacting protein and is phenotypically characterized by fatty liver and elevated plasma triglycerides and VLDL.
Marleen M.J. van Greevenbroek, Vicky M. M-J. Vermeulen, Tjerk W.A. de Bruin   +2 more
doaj   +1 more source

Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males.

PLoS Genetics, 2014
Segregation of chromosomes during the first meiotic division relies on crossovers established during prophase. Although crossovers are strictly regulated so that at least one occurs per chromosome, individual variation in crossover levels is not uncommon.
Brian Baier, Patricia Hunt, Karl W Broman, Terry Hassold   +3 more
doaj   +1 more source

[Biological characterization of clones of the Y, CL and MR strains of Trypanosoma cruzi in inbred C3H mice].

Memorias do Instituto Oswaldo Cruz, 1990
Ten clones of Trypanosoma cruzi isolated from Y, CL and MR strains were studied. The infectivity of culture forms, parasitemia pattern, polymorphism and mortality were studied in C3H inbred mice. Significant intra-group differences among Y and CL clones were found. MR clones showed higher homogeneity. These data indicate that T.
S M, De Araújo, E, Chiari
openaire   +1 more source

Effect of trehalose on the preservation of freeze-dried mice spermatozoa at room temperature

The Journal of Reproduction and Development, 2019
Freeze-drying of spermatozoa is a convenient and safe method to preserve mammalian genetic material without the use of liquid nitrogen or a deep freezer. However, freeze-dried spermatozoa (FD sperm) are not frequently used because of the low success rate
Daiyu ITO, Sayaka WAKAYAMA, Yuko KAMADA, Ikue SHIBASAKI, Satoshi KAMIMURA, Masatoshi OOGA, Teruhiko WAKAYAMA   +6 more
doaj   +1 more source