Results 71 to 80 of about 20,210 (217)

Adipocyte‐specific ablation of plakoglobin in mice does not affect adiposity but results in sexual‐dimorphic effects on weight gain

open access: yesPhysiological Reports, Volume 13, Issue 24, December 2025.
Abstract The main transcriptional coactivator of the WNT pathway, β‐catenin, is a well‐established regulator of adipogenesis and fat expansion, but our knowledge of how other members of the catenin family participate in adipogenesis remains incomplete. Previous studies have elucidated a role for the β‐catenin homolog, plakoglobin, in the regulation of ...
Frederic Abou Azar   +6 more
wiley   +1 more source

Tissue typing by unidirectional mixed lymphocyte culture. I. Demonstration of the cumulative effect of non-H-2 antigens in mice by cultured lymphocytes mixed with cell homogenate [PDF]

open access: yes, 1970
1. The mixed lymphocyte culture test where live lymphocytes of female mice are cultured with supersonicated cell homogenate of isogeneic male mice does not reflect the difference in H-Y histocompatibility antigen alone. 2.
Tsunemitsu, Kensuke
core   +1 more source

Biological sex modulates lung injury severity in adolescent mice exposed to short‐term aerosolized vitamin E acetate

open access: yesPhysiological Reports, Volume 13, Issue 23, December 2025.
Abstract The E‐cigarette or Vaping product‐Associated Lung Injury (EVALI) causes severe acute respiratory failure and, in some cases, death. Most cases are linked to tetrahydrocannabinol‐containing e‐cigarette products adulterated with vitamin E acetate.
Michelle J. Lim   +13 more
wiley   +1 more source

Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice. [PDF]

open access: yesPLoS ONE, 2016
Increased levels of blood plasma urea were used as phenotypic parameter for establishing novel mouse models for kidney diseases on the genetic background of C3H inbred mice in the phenotype-driven Munich ENU mouse mutagenesis project.
Sudhir Kumar   +24 more
doaj   +1 more source

Nicotinamide nucleotide transhydrogenase deficiency and genetic susceptibility to high glucose‐mediated peritoneal injury in mice

open access: yesPhysiological Reports, Volume 13, Issue 22, November 2025.
High‐glucose peritoneal dialysis (PD) fluid induces oxidative stress, inflammation, and fibrosis in the peritoneum. In vivo, Nnt‐deficient C57BL/6J mice showed significantly reduced PD‐induced peritoneal injury, inflammation, and fibrosis compared with Nnt‐competent C57BL/6N controls.
Margarete C. Ohse   +9 more
wiley   +1 more source

Vaccines against toxoplasma gondii : challenges and opportunities [PDF]

open access: yes, 2009
Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Aliberti J   +117 more
core   +3 more sources

Sex differences in voluntary running behavior between C57BL/6 and BALB/cJ mouse strains do not correspond to changes in VO2 and RER

open access: yesPhysiological Reports, Volume 13, Issue 19, October 2025.
Study and results overview. Abstract Exercise adaptations are influenced by sex and genetic background, contributing to variability in metabolic and physiological responses. This study investigates sex and strain‐specific differences following voluntary wheel running exercise training in submaximal and maximal oxygen consumption (VO2), respiratory ...
N. Amiri   +4 more
wiley   +1 more source

Cranial bone morphometric study among mouse strains

open access: yesBMC Evolutionary Biology, 2008
Background Little is known about the molecular mechanism which regulates how the whole cranium is shaped. Mouse models currently available for genetic research include several hundreds of unique inbred strains and genetically engineered mutants. By cross
Yamamura Ken-ichi, Kawakami Minoru
doaj   +1 more source

Susceptibility of inbred mice to Leishmania major infection: genetic analysis of macrophage activation and innate resistance to disease in individual progeny of P/J (susceptible) and C3H/HeN (resistant) mice [PDF]

open access: yesInfection and Immunity, 1990
We tested the possibility that two phenotypic traits, defective activation of macrophage antileishmanial activities and susceptibility to infection with Leishmania major, were controlled by the same gene. We used P/J (susceptible) and C3H/HeN (resistant) mice to breed F1, backcross (Bx), and F2 mice that were tested individually for both traits, each ...
A H, Fortier, A, Tong, C A, Nacy
openaire   +2 more sources

Strongyloides venezuelensis infection susceptibility of seven inbred strains of mice Susceptibilidade de sete linhagens isogênicas de camundongos à infecções por Strongyloides venezuelensis

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2002
A trial was carried out to investigate the susceptibility of seven strains of mice to Strongyloides venezuelensis primary and secondary experimental infections, in order to provide the basis for genetic studies about resistance.
A.F.T. Amarante   +1 more
doaj   +1 more source

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