Results 71 to 80 of about 54,165 (230)

Tissue typing by unidirectional mixed lymphocyte culture. I. Demonstration of the cumulative effect of non-H-2 antigens in mice by cultured lymphocytes mixed with cell homogenate [PDF]

open access: yes, 1970
1. The mixed lymphocyte culture test where live lymphocytes of female mice are cultured with supersonicated cell homogenate of isogeneic male mice does not reflect the difference in H-Y histocompatibility antigen alone. 2.
Tsunemitsu, Kensuke
core   +1 more source

Variability in empathic fear response among 11 inbred strains of mice

open access: yesGenes, Brain and Behavior, 2016
Empathy is an important emotional process that involves the ability to recognize and share emotions with others. We have previously developed an observational fear learning (OFL) behavioral assay to measure empathic fear in mice. In the OFL task, a mouse
S. Keum   +6 more
semanticscholar   +1 more source

Biological sex modulates lung injury severity in adolescent mice exposed to short‐term aerosolized vitamin E acetate

open access: yesPhysiological Reports, Volume 13, Issue 23, December 2025.
Abstract The E‐cigarette or Vaping product‐Associated Lung Injury (EVALI) causes severe acute respiratory failure and, in some cases, death. Most cases are linked to tetrahydrocannabinol‐containing e‐cigarette products adulterated with vitamin E acetate.
Michelle J. Lim   +13 more
wiley   +1 more source

Experimentation with Animals: A Key Aspect of the 3Rs. The Genetic Quality [PDF]

open access: yes, 2019
The genetic quality of laboratory animals is essential for reproducibility of scientific research. Working with animals of certifiedgenetic quality is still a pending issue in Argentina due to the lack of routine genetic controls, of information on the ...
Castillo, Nadia Sabiela   +4 more
core   +1 more source

Temporal dynamics of the developing lung transcriptome in three common inbred strains of laboratory mice reveals multiple stages of postnatal alveolar development

open access: yesPeerJ, 2016
To characterize temporal patterns of transcriptional activity during normal lung development, we generated genome wide gene expression data for 26 pre- and post-natal time points in three common inbred strains of laboratory mice (C57BL/6J, A/J, and C3H ...
Kyle J. Beauchemin   +7 more
semanticscholar   +1 more source

Nicotinamide nucleotide transhydrogenase deficiency and genetic susceptibility to high glucose‐mediated peritoneal injury in mice

open access: yesPhysiological Reports, Volume 13, Issue 22, November 2025.
High‐glucose peritoneal dialysis (PD) fluid induces oxidative stress, inflammation, and fibrosis in the peritoneum. In vivo, Nnt‐deficient C57BL/6J mice showed significantly reduced PD‐induced peritoneal injury, inflammation, and fibrosis compared with Nnt‐competent C57BL/6N controls.
Margarete C. Ohse   +9 more
wiley   +1 more source

Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice. [PDF]

open access: yesPLoS ONE, 2016
Increased levels of blood plasma urea were used as phenotypic parameter for establishing novel mouse models for kidney diseases on the genetic background of C3H inbred mice in the phenotype-driven Munich ENU mouse mutagenesis project.
Sudhir Kumar   +24 more
doaj   +1 more source

Age- and Strain-Related Differences in Bone Microstructure and Body Composition During Development in Inbred Male Mouse Strains

open access: yesCalcified Tissue International, 2020
We explored age- and strain-related differences in bone microstructure and body composition in male C57BL/6J, DBA/2JRj and C3H/J mice. Bone microstructure of the femur, tibia and L4 was assessed by μCT at the age of 8, 16 and 24 weeks.
M. Papageorgiou   +4 more
semanticscholar   +1 more source

Sex differences in voluntary running behavior between C57BL/6 and BALB/cJ mouse strains do not correspond to changes in VO2 and RER

open access: yesPhysiological Reports, Volume 13, Issue 19, October 2025.
Study and results overview. Abstract Exercise adaptations are influenced by sex and genetic background, contributing to variability in metabolic and physiological responses. This study investigates sex and strain‐specific differences following voluntary wheel running exercise training in submaximal and maximal oxygen consumption (VO2), respiratory ...
N. Amiri   +4 more
wiley   +1 more source

Cranial bone morphometric study among mouse strains

open access: yesBMC Evolutionary Biology, 2008
Background Little is known about the molecular mechanism which regulates how the whole cranium is shaped. Mouse models currently available for genetic research include several hundreds of unique inbred strains and genetically engineered mutants. By cross
Yamamura Ken-ichi, Kawakami Minoru
doaj   +1 more source

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