Results 241 to 250 of about 428,092 (271)

Siglec-15 is a putative receptor for porcine epidemic diarrhea virus infection. [PDF]

Cell Mol Life Sci
Feng Z, Fu Y, Yang S, Zhao H, Lin M, Liu C, Huang W, He X, Chen Y, Chen J, Shen Y, Li Z, Chen Q.   +12 more
europepmc   +1 more source

Correction: Yin et al. Angiogenesis-Browning Interplay Mediated by Asprosin-Deficiency Contributes to Weight Loss in Mice with Obesity. <i>Int. J. Mol. Sci.</i> 2022, <i>23</i>, 16166. [PDF]

Int J Mol Sci
Yin T, Chen S, Zeng G, Yuan W, Lu Y, Zhang Y, Huang Q, Xiong X, Xu B, Huang Q.   +9 more
europepmc   +1 more source

Activated Microglia Mediate the Motor Neuron-, Synaptic Denervation- and Muscle Wasting-Changes in Burn Injured Mice. [PDF]

J Cachexia Sarcopenia Muscle
Chen J, Kitagawa Y, Xie F, Li H, Kem WR, You Z, Yasuhara S, Martyn JAJ.   +7 more
europepmc   +1 more source

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Knockout Mice in Xenobiotic Metabolism

Drug Metabolism Reviews, 2003
Mice in which genes for drug metabolizing enzymes have been deleted or inactivated have great potential to further our understanding of the functions of these enzymes and their role in toxicology a...
Henderson, Colin J., Otto, Diana M. E., McLaren, Aileen W., Carrie, Dianne, Wolf, C. Roland   +4 more
openaire   +4 more sources

Rescue of Angiotensinogen-Knockout Mice

Biochemical and Biophysical Research Communications, 1998
Angiotensinogen, the precursor of angiotensins I and II, is a critical component of the renin-angiotensin system that plays an important role in regulating blood pressure and electrolyte homeostasis. Genetically altered mice lacking angiotensinogen (Agt-KO) showed an expected phenotype, such as marked hypotension, but unexpected ones including abnormal
K. Taniguchi, Kazuo Murakami, Ken-ichi Yagami, Hisashi Horiguchi, Keiji Tanimoto, Eriko Takimoto, Junji Ishida, Akiyoshi Fukamizu, Fumihiro Sugiyama, Mikio Syouji   +9 more
openaire   +3 more sources

ChemInform Abstract: Serine Racemase Knockout Mice [PDF]

ChemInform, 2010
AbstractReview: 35 refs.
Hisashi Mori, Ran Inoue
openaire   +3 more sources

Xenobiotic receptor knockout mice

Toxicology Letters, 1995
Administration of certain foreign chemicals to animals elicits responses that are due to receptor-mediated activation of gene expression. Among the most well studied receptors are the Ah receptor (AHR) that binds 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds and the peroxisome proliferator-activated receptors, PPARs, that mediate gene ...
Pedro M. Fernández-Salguero, Jerrold M. Ward, Frank J. Gonzalez, Thierry Pineau, Susanna S.T. Lee   +4 more
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Generating Conditional Knockout Mice

2010
Gene targeting in ES cells is extensively used to generate designed mouse mutants and to study gene function in vivo. Knockout mice that harbor a null allele in their germline provide appropriate genetic models of inherited diseases and often exhibit embryonic or early postnatal lethality. To study gene function in adult mice and in selected cell types,
Benedikt Wefers, Roland H. Friedel, Ralf Kühn, Wolfgang Wurst   +3 more
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Insulin Receptor Knockout Mice

Annual Review of Physiology, 2003
▪ Abstract  To examine the role of the insulin receptor in fuel homeostasis, we and others have carried out genetic ablation studies in mice. Mice lacking insulin receptors are born with normal features, but develop early postnatal diabetes and die of ketoacidosis.
Domenico Accili, Tadahiro Kitamura, C. Ronald Kahn   +2 more
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Knockout mice for dummies

Molecular Medicine Today, 1999
Gene targeting has become an extremely popular method for generating mouse models of human disease. The targeting event is carried out in vitro in pluripotent embryonic stem (ES) cells, which are then used to generate chimeric founder animals by either fusion with early-stage embryos or direct injection into donor blastocysts.
openaire   +2 more sources