Hormonal and enzymatic analysis for pancreas of diabetic and obese mice in Iraq [PDF]
Caspian Journal of Environmental Sciences, 2022 For our knowledge, this appears to be first Iraqi study aimed for detection the concentration of pancreatic exocrine enzymes and endocrine hormones as well as lipid profile in obese, diabetic as well as obese/diabetic mice.
Nasreen Habib Humaidan Al-Moussawi
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PLoS ONE, 2022 BackgroundNon-alcoholic fatty liver disease (NAFLD) ranks first among liver diseases in Western countries. NAFLD is typically associated with obesity and diabetes, however it also develops in lean individuals without metabolic syndrome. The prevalence of
Emma Hymel +3 more
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Obesity Alters cytokine signaling and gut microbiome in septic mice
Innate Immunity, 2023 Sepsis is a leading cause of mortality. Plasma cytokine levels may identify those at increased risk of mortality from sepsis. Our aim was to understand how obesity alters cytokine levels during early sepsis and its correlation with survival. Six-week-old
Lauren Bodilly +5 more
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Cell Death Discovery, 2023 Obese people with acute pancreatitis (AP) have an increased risk of developing severe acute pancreatitis (SAP), which prolongs the length of hospital stay and increases mortality.
Kunlei Wang +10 more
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Cilia, tubby mice, and obesity [PDF]
Cilia, 2013 Primary cilia have been previously linked to the central regulation of satiety. The tubby mouse is characterized by maturity-onset obesity and blindness. A recent paper demonstrates molecular defects in trafficking of ciliary GPCRs in the central neurons of tubby mice, underscoring the role of ciliary signaling in the pathogenesis of this monogenic ...
Mukhopadhyay, Saikat, Jackson, Peter K
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Activating brown adipose tissue for weight loss and lowering of blood glucose levels: a microPET study using obese and diabetic model mice. [PDF]
PLoS ONE, 2014 PURPOSE: This study aims at using 18F-FDG microPET to monitor the brown adipose tissue (BAT) glucose metabolism in obese and diabetic mouse models under different interventions, and study the therapeutic potential of BAT activation for weight loss and ...
Chenxi Wu +8 more
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Exercise Improves Host Response to Influenza Viral Infection in Obese and Non-Obese Mice through Different Mechanisms. [PDF]
PLoS ONE, 2015 Obesity has been associated with greater severity of influenza virus infection and impaired host defense. Exercise may confer health benefits even when weight loss is not achieved, but it has not been determined if regular exercise improves immune ...
Kristi J Warren +7 more
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Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue [PDF]
Korean Journal of Pediatrics, 2013 PurposeWe investigated the mRNA levels of peroxisome proliferator-activated receptor (PPAR)-α, PPAR-γ, adipokines, and cytokines in the lung tissue of lean and obese mice with and without ovalbumin (OVA) challenge, and the effect of rosiglitazone, a PPAR-
Seung Lok Ryu +8 more
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Fish oil suppresses obesity more potently in lean mice than in diet-induced obese mice but ameliorates steatosis in such obese mice [PDF]
Bioscience, Biotechnology, and Biochemistry, 2021 ABSTRACT This study sought to clarify the antiobesity effects of fish oil (FO) in terms of prevention and amelioration. An isocaloric diet composed of lard or FO was given to lean C57BL/6J mice for the study of prevention and high-fat diet-induced obese (DIO) mice for the study of amelioration for 4 weeks.
Sachiko, Okue +9 more
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Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. [PDF]
PLoS ONE, 2013 A positive relationship between obesity and asthma has been well documented. The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses.
Marina Ciarallo Calixto +9 more
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