Results 31 to 40 of about 239,216 (213)
Alcohol produces distinct hepatic lipidome and eicosanoid signature in lean and obese[S]
Journal of Lipid Research, 2016 Alcohol- and obesity-related liver diseases often coexist. The hepatic lipidomics due to alcohol and obesity interaction is unknown. We characterized the hepatic lipidome due to 1) alcohol consumption in lean and obese mice and 2) obesity and alcohol ...
Puneet Puri +10 more
doaj +1 more source
Adipose-derived mesenchymal stem cells from obese mice prevent body weight gain and hyperglycemia
Stem Cell Research & Therapy, 2021 Changes that occur to the stem cell microenvironment with disease are a major consideration that may affect the behavior and potential therapeutic efficacy of mesenchymal stem cells (MSCs).
Yicheng Qi +9 more
doaj +1 more source
Frontiers in Nutrition, 2021 Resolvin E1 (RvE1) is an immunoresolvent that is synthesized from eicosapentaenoic acid and can bind the receptor ERV1/ChemR23. We previously showed activation of the RvE1-ChemR23 axis improves hyperglycemia and hyperinsulinemia of obese mice; however ...
Abrar E. Al-Shaer +2 more
doaj +1 more source
PI3Kα inhibition reduces obesity in mice
Aging, 2016 Partial inhibition of PI3K is one of the best-validated and evolutionary conserved manipulations to extend longevity. The best known health beneficial effects of reduced PI3K are related to metabolism and include increased energy expenditure, reduced nutrient storage, and protection from obesity.
Lopez-Guadamillas, Elena +5 more
openaire +3 more sources
Malaria and obesity: obese mice are resistant to cerebral malaria [PDF]
Malaria Journal, 2008 The relationship between malaria and obesity are largely unknown. This is partly due to the fact that malaria occurs mainly in tropical areas where, until recently, obesity was not prevalent. It now appears, however, that obesity is emerging as a problem in developing countries.
Robert, Vincent +5 more
openaire +4 more sources
Respiratory Research, 2020 Background Previously, it has been shown that obesity is a risk factor for recovery, regeneration, and tissue repair after blunt trauma and can affect the rate of muscle recovery and collagen deposition after trauma. To date, lung tissue regeneration and
Pengfei Xu +7 more
doaj +1 more source
Animal models of NASH: getting both pathology and metabolic context right [PDF]
, 2015 Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core +1 more source
Obesity impairs resistance to Leishmania major infection in C57BL/6 mice.
PLoS Neglected Tropical Diseases, 2020 An association between increased susceptibility to infectious diseases and obesity has been described as a result of impaired immunity in obese individuals. It is not clear whether a similar linkage can be drawn between obesity and parasitic diseases. To
Vinicius Dantas Martins +12 more
doaj +1 more source
Physical outcome measure for critical care patients following intensive care discharge [PDF]
, 2016 Introduction: The aim of this study was to evaluate the most suitable physical outcome measures to be used with critical care patients following discharge. ICU survivors experience physical problems such as reduced exercise capacity and intensive care
Daniel, M +5 more
core +1 more source
International Journal of Endocrinology, 2015 Objective. Tauroursodeoxycholic acid (TUDCA) has been considered an important regulator of energy metabolism in obesity. However, the mechanism underlying how TUDCA is involved in insulin resistance is not fully understood. We tested the effects of TUDCA
Qinyue Guo +6 more
doaj +1 more source