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Fluorapatite: efficient catalyst for the Michael addition

Tetrahedron Letters, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Mohamed Zahouily   +2 more
exaly   +2 more sources

How Dihalogens Catalyze Michael Addition Reactions

open access: yesAngewandte Chemie - International Edition, 2019
We have quantum chemically analyzed the catalytic effect of dihalogen molecules (X2 = F2, Cl2 , Br2, and I2) on the aza-Michael addition of pyrrolidine and methyl acrylate using relativistic density functional theory and coupled-cluster theory. Our state-
Trevor A Hamlin, F Matthias Bickelhaupt
exaly   +2 more sources

Rotaxanes via Michael Addition

Organic Letters, 2000
[reaction: see text] The application of a template effect to the classical Michael addition of heteronucleophiles to various Michael acceptor systems leads in good yields to a new trapping synthesis of [2]rotaxanes with conjugated functional groups in their axles.
, Reuter, , Vogtle
openaire   +2 more sources

Michael additions of benzoins versus Michael-Stetter additions of aldehydes

Tetrahedron Letters, 1980
Abstract Triethylamine catalyzed Michael additions of benzoins to chalcone can prevail over the expected Michael-Stetter additions when certain thiazolium ion conjugate bases - prepared in situ from the pertinent thiazolium salts and triethylamine- are used as catalysts.
Josep Castells   +6 more
openaire   +1 more source

Michael additions in polyketide biosynthesis

Natural Product Reports, 2019
Enzymes that catalyze a Michael-type addition in polyketide biosynthesis are summarized and discussed.
openaire   +2 more sources

The stereochemistry of the Michael addition

Tetrahedron, 1968
Abstract The nature of the products obtained in the addition of diethyl malonate to 4-t-butyl-1-cyanocyclohexene under various conditions of solvents, catalysts, and temperature, and their geometries have been determined. In protic solvents, and under conditions of kinetic control, the main product is diethyl cis -t-butyl-1-cyano-2 ...
R.A. Abramavitch, D.L. Struble
openaire   +1 more source

Michael addition of artemisitene

Tetrahedron Letters, 2001
Abstract Michael addition of artemisitene with triazole, benzotriazole or benzimidazole under non- or base-catalyzed conditions yielded compounds 3a – c and 4a – c . They showed high antimalarial activity against Plasmodium berghei in mice.
Xi-Bin Liao, Ji-Ye Han, Ying Li
openaire   +1 more source

Acid catalyzed michael additions to artemisitene

Bioorganic & Medicinal Chemistry Letters, 2000
A series of 14-substituted-artemisinin and 9-epiartemisinin derivatives was prepared by a titanium-tetrachloride catalyzed addition of trimethylsilyl enol ethers to artemisitene. Several compounds were four to seven times more active than artemisinin against Plasmodium falciparum.
J, Ma, E, Weiss, D E, Kyle, H, Ziffer
openaire   +2 more sources

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