Results 261 to 270 of about 9,761,251 (311)
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Michael Addition of Manganese Enolates to Nitroolefins
Synlett, 2007The Michael addition to nitroolefins of manganese enolates derived from an array of ketones is reported. The desired 1,4-adducts are obtained in high yield and excellent diastereo- and regioselectivity, the sole kinetic adduct being obtained in the case of nonsymmetrical ketones.
Micheletti G. +4 more
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Michael addition drugs and cancer
Some of the earliest anticancer drugs were alkylating agents, capable of covalently modifying critical cellular nucleophiles in proteins and nucleic acids. For many years, adapting another type of covalent reaction, Michael addition reactions, which involve the nucleophilic attack of a carbon nucleophile on an α,β-unsaturated carbonyl compound, have ...Kenneth D, Tew +5 more
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ChemInform Abstract: MICHAEL ADDITIONS OF BENZOINS VERSUS MICHAEL‐STETTER ADDITIONS OF ALDEHYDES
Chemischer Informationsdienst, 1980AbstractBei der Addition von Aldehyden an Chalkon (II) nach Michael‐Stetter spielt die sterische Hinderung in den verwendeten Thiazoliumsalz‐Katalysatoren (III) eine wesentliche Rolle; aus Furfural (I) und (II) erhält man unterschiedliche Anteile an den Addukten (IV) und (V) über diskutierte Zwischenstufen.
J. CASTELLS +6 more
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Organocatalytic Asymmetric Aza‐Michael Additions
Chemistry – A European Journal, 2009AbstractThe catalytic aza‐Michael addition is an important reaction within synthetic organic chemistry, given the significance of the biologically and synthetically interesting products, such as β‐amino acids and β‐lactams. In the last decade organocatalysis emerged as a powerful tool in asymmetric synthesis and had a large impact on the development of
Dieter, Enders +2 more
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Michael Addition of Glucosamines
1992Three primary amines and one secondary amine were used as model compounds for the proposed Michael addition of glucosamine to five ∞,B-unsaturated carbonyls. The products were identified and partially characterized using boiling points, melting points, infrared spectra, and gas chromatography.
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