Results 301 to 310 of about 1,004,074 (357)

Stetter reaction (Michael-Stetter reaction)

2002
1,4-Dicarbonyl derivatives from aldehydes and α,(β-unsaturated ketones. The thiazolium catalyst serves as a safe surrogate for −CN. Cf. Benzoin condensation.
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Catalysis of the Michael reaction

Tetrahedron Letters, 1985
Abstract Two nearly equivalent procedures have been evolved for catalysis of the Michael reaction : (i) potassium t -butoxide deposited on xonotlite; and (ii) alumina supported potassium fluoride. These catalysts will undergo 150+ turnovers and enable Michael additions to be run at room temperature or below in good yields.
Pierre Laszlo, Pascal Pennetreau
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Discovery of the Michael Reaction

European Journal of Organic Chemistry, 2010
AbstractThis essay deals with the details of the discovery of the Michael addition reaction, focusing on Arthur Michael, an American chemist, after whom it is named. Michael envisaged the possibility of an addition reaction of sodiomalonate ester or sodioacetoacetate ester to α,β‐unsaturated acid esters and confirmed this by experimentation.
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Tandem Michael/Michael Reactions Mediated by Phosphines or Aryl Thiolates.

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Brown, Paul M., Käppel, Nina, Murphy, Patrick J., Coles, Simon J., Hursthouse, Michael B.   +4 more
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Tandem Michael/Michael reactions mediated by phosphines or aryl thiolates

Tetrahedron Letters, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Paul M. Brown, Nina Kaeppel, Patrick J. Murphy   +2 more
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Catalytic, enantioselective vinylogous Michael reactions

Organic & Biomolecular Chemistry, 2014
Recent progress in the field of catalytic, enantioselective vinylogous Michael reactions of latent dienolates is described which furnish optically highly enriched chiral 1,7-dioxo compounds of great utility in one synthetic operation. Emphasis is given to new catalysis modes which realise this challenging transformation with high regio- as well as ...
Christoph, Schneider, Falko, Abels
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Difluoronitromethane in the Michael reaction

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1979
The reaction proceeds only upon prolonged heating of an equimolar mixture in a sealed ampul at I00-130~ EtONa and K2C03 were used as catalysts. (Ia): 13% yield; bp 98~ (25 mm); d~ ~ 1.312; n~ ~ 1.4045. Found, %: C 31.81; H 2.87; F 25.17; N 18.50. C4H4F2N202. Calculated, %: C 32.00; H 2.67; F 25.33; N 18.67. 19F N~ spectrum (CF3COOH, 6, ppm): 9.25 t, JF-
A. V. Fokin, A. N. Voronkov
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Catalytic Asymmetric Michael Reactions of Acetaldehyde

Angewandte Chemie International Edition, 2008
Acetaldehyde, now a big contender: A silyl prolinol derivative was found to catalyze the first Michael addition of acetaldehyde with both aromatic and aliphatic nitroolefins in excellent enantioselectivities (see scheme, TMS=trimethylsilyl). The utility of the reaction is illustrated in the synthesis of three current pharmaceuticals and in the ...
García‐García, P., Ladépêche, A., Halder, R., List, B.   +3 more
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Vinylogous Mukaiyama–Michael Reactions of Dihydropyridinones

Organic Letters, 2015
An In(III)-catalyzed vinylogous addition of O-silyl vinylketene acetals to 2,3-dihydro-4-pyridinones has been developed. The method features the unprecedented employment of supersilyl groups to influence the γ versus α regiochemical control of vinylogous Mukaiyama-Michael (vM-Michael) reactions when γ-substituted O-silyl vinylketene acetals are used ...
Hui, Li, Jimmy, Wu
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The Stereochemical Course of Intramolecular Michael Reactions

The Journal of Organic Chemistry, 2012
We present a general model for understanding the stereochemical course of intramolecular Michael reactions. We show that the addition of β-ketoester enolates to α,β-unsaturated esters and imides bearing adjacent stereocenters (X, Y = H, Me, OR) leads to high levels of asymmetric induction. Reinforcing and nonreinforcing stereochemical relationships are
Eugene E, Kwan, Jonathan R, Scheerer, David A, Evans   +2 more
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