Results 71 to 80 of about 6,596 (159)

Closing the Gap: Membrane Contact Sites in the Regulation of Autophagy

Cells, 2020
In all eukaryotic cells, intracellular organization and spatial separation of incompatible biochemical processes is established by individual cellular subcompartments in form of membrane-bound organelles.
Verena Kohler, Andreas Aufschnaiter, Sabrina Büttner   +2 more
doaj   +1 more source

ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter‐Strategies

Molecular Plant Pathology, Volume 27, Issue 6, June 2026.
The endosomal sorting complex required for transport (ESCRT) plays multifaceted roles in plants' responses to pathogens, including regulation of the localization and fate of immune receptors and other related cellular processes. ABSTRACT The endosomal sorting complex required for transport (ESCRT) machinery consists of multiprotein complexes conserved ...
Willam Kyle Sexton, Shunyuan Xiao
wiley   +1 more source

Microautophagy: current understanding of its molecular mechanisms and functions

Autophagy Reports
Microautophagy (MI-autophagy) is an umbrella term for intracellular degradative pathways that entail the invagination or protrusion of the limiting membranes of endolysosomal compartments, that is, late endosomes and mammalian lysosomes or yeast and ...
Yasuyoshi Sakai, Christian Behrends, Jayanta Debnath, Masanori Izumi, Andreas Jenny, Maurizio Molinari, Shuhei Nakamura, Masahide Oku, Marisa S. Otegui, Laura Santambrogio, Han-Ming Shen, Tomohiko Taguchi, Michael Thumm, Takashi Ushimaru, Zhiping Xie, Ana Maria Cuervo, Fulvio Reggiori   +16 more
doaj   +1 more source

Forms, Crosstalks, and the Role of Phospholipid Biosynthesis in Autophagy

International Journal of Cell Biology, 2012
Autophagy is a highly conserved cellular process occurring during periods of stress to ensure a cell's survival by recycling cytosolic constituents and making products that can be used in energy generation and other essential processes. Three major forms
Leanne Pereira, John Paul Girardi, Marica Bakovic   +2 more
doaj   +1 more source

The vacuolar transporter chaperone (VTC) complex is required for microautophagy

, 2007
Microautophagy involves direct invagination and fission of the vacuolar/lysosomal membrane under nutrient limitation. This occurs by an autophagic tube, a specialized vacuolar membrane invagination that pinches off vesicles into the vacuolar lumen.
Schwarz, H., Uttenweiler, A., Mayer, A., Neumann, H.   +3 more
core   +1 more source

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

Lysosomal Biology and Function: Modern View of Cellular Debris Bin

Cells, 2020
Lysosomes are the main proteolytic compartments of mammalian cells comprising of a battery of hydrolases. Lysosomes dispose and recycle extracellular or intracellular macromolecules by fusing with endosomes or autophagosomes through specific waste ...
Purvi C. Trivedi, Jordan J. Bartlett, Thomas Pulinilkunnil   +2 more
doaj   +1 more source

The Hansenula polymorpha PDD7 gene is essential for macropexophagy and microautophagy [PDF]

, 2003
Hansenula polymorpha PDD genes are involved in the selective degradation of peroxisomes via macropexophagy. We have isolated various novel pdd mutants by a gene-tagging method.
Veenhuis, M, Kiel, JAKW, Veenhuis, Marten,, Kiel, Jan A.K.W.,, Komduur, Janet A.,, Komduur, JA   +5 more
core   +2 more sources

Determination of four sequential stages during microautophagy in vitro.

, 2004
Microautophagy is the transfer of cytosolic components into the lysosome by direct invagination of the lysosomal membrane and subsequent budding of vesicles into the lysosomal lumen.
Schwarz, H., Kunz, J. B., Schwarz, Heinz, Kunz, J.B., Kunz, J., Mayer, A.   +5 more
core   +1 more source

Atg21p is essential for macropexophagy and microautophagy in the yeast Hansenula polymorpha [PDF]

, 2004
ATG genes are required for autophagy-related processes that transport proteins/organelles destined for proteolytic degradation to the vacuole. Here, we describe the identification and characterisation of the Hansenula polymorpha ATG21 gene.
Ida J. van der Klei, Kiel, Jan A.K.W., Gellissen, Gerd, Krikken, Arjen M; id_orcid, Arjen M. Krikken, Kiel, Jan A K W, Adriana N. Leão-Helder, Gerd Gellissen, van der Klei, Ida J., van der Klei, Ida J, Krikken, Arjen M, Leão-Helder, Adriana N., Krikken, Arjen M., Jan A.K.W. Kiel, van der Klei, Ida J; id_orcid, Marten Veenhuis, Veenhuis, Marten, Leão-Helder, Adriana N   +17 more
core   +3 more sources