Recent advances in the application of microbiota transplantation in chickens [PDF]
Extensive evidence demonstrates that a healthy and well-balanced gut microbiota profoundly influences host nutrient absorption, immunity, and metabolism.
Haoran Zhao+5 more
doaj +2 more sources
Patent Human Infections with the Whipworm, Trichuris trichiura, Are Not Associated with Alterations in the Faecal Microbiota [PDF]
Background: The soil-transmitted helminth (STH), Trichuris trichiura colonises the human large intestine where it may modify inflammatory responses, an effect possibly mediated through alterations in the intestinal microbiota.
A Olsen+46 more
core +18 more sources
Gut microbiome signatures reflect different subtypes of irritable bowel syndrome
Irritable bowel syndrome (IBS) is a heterogeneous condition with multifactorial pathogenesis. We studied deeply phenotyped individuals with microbiota sequencing enrolled in the American Gut Project.
Qi Su+6 more
doaj +1 more source
Faecal microbiome-based machine learning for multi-class disease diagnosis
Here, using fecal metagenomics data of 2,320 individuals, the authors develop a microbiome-based machine learning approach showing high accuracy for multi-class disease diagnosis, highlighting its potential application in improving noninvasive ...
Qi Su+19 more
doaj +1 more source
Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines
The role of gut microbiota in modulating the durability of COVID-19 vaccine immunity is yet to be characterised. In this cohort study, we collected blood and stool samples of 121 BNT162b2 and 40 CoronaVac vaccinees at baseline, 1 month, and 6 months post
Ye Peng+21 more
doaj +1 more source
Microbiota in health and diseases
The role of microbiota in health and diseases is being highlighted by numerous studies since its discovery. Depending on the localized regions, microbiota can be classified into gut, oral, respiratory, and skin microbiota.
Kaijian Hou+10 more
semanticscholar +1 more source
Here, Forster et al. compare 1354 cultured commensal strains (540 species) to 45,403 pathogen strains (12 species), identifying 64,188 MGE-mediated antibiotic resistance gene transfer events between the two groups, and show that 15 broad host range MGEs ...
Samuel C. Forster+12 more
doaj +1 more source
Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle
Background Human-to-human transmission of symbiotic, anaerobic bacteria is a fundamental evolutionary adaptation essential for membership of the human gut microbiota.
Hilary P. Browne+10 more
doaj +1 more source
Multi-kingdom gut microbiota analyses define COVID-19 severity and post-acute COVID-19 syndrome
Here, by performing an integrative multi-omics analysis coupled to clinical features of COVID-19 patients prospectively followed for up to 6 month, the authors identify specific gut microbiome patterns associated with disease severity and development of ...
Qin Liu+15 more
doaj +1 more source
Interaction between microbiota and immunity in health and disease
The interplay between the commensal microbiota and the mammalian immune system development and function includes multifold interactions in homeostasis and disease. The microbiome plays critical roles in the training and development of major components of
D. Zheng, T. Liwinski, E. Elinav
semanticscholar +1 more source