Results 41 to 50 of about 356,233 (321)
mSystems, 2022 Understanding the role of fecal microbiota transplantation (FMT) in the decolonization of multidrug-resistant organisms (MDRO) is critical. Specifically, little is known about virome changes in MDRO-infected subjects treated with FMT.
Qin Liu +18 more
doaj +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source
Social interaction, noise and antibiotic-mediated switches in the intestinal microbiota [PDF]
, 2012 The intestinal microbiota plays important roles in digestion and resistance against entero-pathogens. As with other ecosystems, its species composition is resilient against small disturbances but strong perturbations such as antibiotics can affect the consortium dramatically.
arxiv +1 more source
Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis [PDF]
Nat. Commun. 8, 15393 (2017), 2017 A system-level framework of complex microbe-microbe and host-microbe chemical cross-talk would help elucidate the role of our gut microbiota in health and disease. Here we report a literature-curated interspecies network of the human gut microbiota, called NJS16.
arxiv +1 more source
Revista de la Sociedad Argentina de Diabetes, 2020 La microbiota intestinal se considera un órgano que posee un importante impacto en la salud del huésped, cuya formación en los dos y tres primeros años de vida es clave en el futuro desarrollo de la salud/enfermedad del individuo.
openaire +3 more sources
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
FEBS Open Bio, EarlyView.With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet +6 more
wiley +1 more source
Nature Communications, 2021 Spores produced by Clostridioides difficile during infection are important for the recurrence of the disease. Here, Castro-Córdova et al. show that the spores gain entry into the intestinal mucosa via pathways dependent on host fibronectin and ...
Pablo Castro-Córdova +10 more
doaj +1 more source
Frontiers in Pediatrics, 2019 During the last several years, the interest in the role of microbiota in human health has grown significantly. For many years, the lung was considered a sterile environment, and only recently, with the use of more sophisticated techniques, has it been demonstrated that colonization by a complex population of microorganisms in lower airways also occurs ...
Salvatore Savasta +9 more
openaire +8 more sources
Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan +7 more
wiley +1 more source
Microbiota, Food, and Health [PDF]
International Journal of Molecular Sciences, 2019 The effects of specific foods, such as products containing probiotics or prebiotics, on human health and the role of intestinal microbiota in this interaction have been a subject of scientific interest for several decades [...]
Kirsi Laitinen, Miguel Gueimonde
openaire +4 more sources