Results 61 to 70 of about 913,863 (385)

Lacticaseibacillus paracasei sh2020 induced antitumor immunity and synergized with anti-programmed cell death 1 to reduce tumor burden in mice

Gut Microbes, 2022
The gut microbiota was emerging as critical regulatory elements in shaping the outcome of cancer immunotherapy. However, the underlying mechanisms by which the gut commensal species enhance antitumor immunity remain largely unexplored. Here, we show that
Shi-Long Zhang, Bing Han, Yu-Qin Mao, Zheng-Yan Zhang, Zhan-Ming Li, Chao-Yue Kong, You Wu, Guo-Qiang Chen, Li-Shun Wang   +8 more
doaj   +1 more source

Role of gut microbiota in the aetiology of obesity: proposed mechanisms and review of the literature [PDF]

, 2016
The aetiology of obesity has been attributed to several factors (environmental, dietary, lifestyle, host, and genetic factors); however none of these fully explain the increase in the prevalence of obesity worldwide.
Edwards, Christine Ann, Gerasimidis, Konstantinos, Khan, Muhammad Jaffar, Shaikh, M. Guftar   +3 more
core   +3 more sources

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

Signal Transduction and Targeted Therapy
The human gastrointestinal tract is populated with a diverse microbial community. The vast genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every aspect of human biology, including health maintenance, development ...
Jian Sheng Loh, Wen Qi Mak, Lily Tan, Chu Xin Ng, Hong Hao Chan, Shiau Hueh Yeow, J. Foo, Y. Ong, C. W. How, K. Khaw   +9 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Associations among Wine Grape Microbiome, Metabolome, and Fermentation Behavior Suggest Microbial Contribution to Regional Wine Characteristics. [PDF]

, 2016
UnlabelledRegionally distinct wine characteristics (terroir) are an important aspect of wine production and consumer appreciation. Microbial activity is an integral part of wine production, and grape and wine microbiota present regionally defined ...
Allen, Greg, Bokulich, Nicholas A, Collins, Thomas S, Ebeler, Susan E, Heymann, Hildegarde, Masarweh, Chad, Mills, David A   +6 more
core   +2 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Honeybees fed D-galactose exhibit aging signs with changes in gut microbiota and metabolism

mSystems
Honeybees (Apis mellifera), as social insects, exhibit complex social behaviors and cognitive functions. The short lifespan and stable gut microorganisms of honeybees provide certain availability as a rapid and high-flux animal model for aging research ...
Guanzhou Zhou, Jiabin Hu, Mengqi Xu, Yiyuan Li, Ruqi Chang, Jiaqi Zeng, Wanyue Dan, Lihua Peng, Zikai Wang, Gang Sun, Fei Pan, Yunsheng Yang   +11 more
doaj   +1 more source

The Effect of Secondary Metabolites Produced by Serratia marcescens on Aedes aegypti and Its Microbiota

Frontiers in Microbiology, 2021
Serratia marcescens is a bacterial species widely found in the environment, which very efficiently colonizes mosquitoes. In this study, we isolated a red-pigmented S. marcescens strain from our mosquito colony (called S. marcescens VA).
Katy Heu, Ottavia Romoli, Johan Claes Schönbeck, Rachel Ajenoe, Yanouk Epelboin, Verena Kircher, Emeline Houël, Yannick Estevez, Mathilde Gendrin, Mathilde Gendrin   +9 more
doaj   +1 more source

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

Journal of Lipid Research, 2013
Short-chain fatty acids (SCFAs), the end products of fermentation of dietary fibers by the anaerobic intestinal microbiota, have been shown to exert multiple beneficial effects on mammalian energy metabolism.
G. den Besten, K. van Eunen, A. Groen, K. Venema, D. Reijngoud, Barbara M. Bakker   +5 more
semanticscholar   +1 more source

MICROBIOTA

Revista de la Sociedad Argentina de Diabetes, 2020
La microbiota intestinal se considera un órgano que posee un importante impacto en la salud del huésped, cuya formación en los dos y tres primeros años de vida es clave en el futuro desarrollo de la salud/enfermedad del individuo.
openaire   +3 more sources