Results 61 to 70 of about 356,233 (321)

Microbiota and Autoimmunity [PDF]

Cold Spring Harbor Perspectives in Biology, 2013
The commensal microbiota affects many aspects of mammalian health including control of the immune system to such a extent that a "commensalocentric" view of the maintenance of overall health could be suggested. Autoimmunity is a case of mistaken identity: The immune system reacts to self-tissues and cells as if they were pathogens. Autoimmune reactions
openaire   +2 more sources

Short‐Chain Fatty Acids Modulate Anti‐ROR1 CAR T‐Cell Function and Exhaustion in an Intestinal Adenocarcinoma‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner, Adrian Feile, Miriam Alb, Michael Hudecek, Philip Hewitt, Alexander S. Mosig   +5 more
wiley   +1 more source

Assessing the impact of hatching system and body weight on the growth performance, caecal short-chain fatty acids, and microbiota composition and functionality in broilers

Animal Microbiome
Background Variations in body weight (BW) remain a significant challenge within broiler flocks, despite uniform management practices. Chicken growth traits are influenced by gut microbiota, which are in turn shaped by early-life events like different ...
Muhammad Zeeshan Akram, Ester Arévalo Sureda, Luke Comer, Matthias Corion, Nadia Everaert   +4 more
doaj   +1 more source

The tripartite interactions between the mosquito, its microbiota and Plasmodium

Parasites & Vectors, 2018
The microbiota of Anopheles mosquitoes interferes with mosquito infection by Plasmodium and influences mosquito fitness, therefore affecting vectorial capacity.
Ottavia Romoli, Mathilde Gendrin
doaj   +1 more source

Reduction of Alzheimer's disease beta-amyloid pathology in the absence of gut microbiota [PDF]

arXiv, 2015
Alzheimer's disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder. Despite clinical and experimental evidence implicating the intestinal microbiota in a number of brain disorders, its impact on Alzheimer's disease is not known.
arxiv  

Rough Set Microbiome Characterisation [PDF]

arXiv, 2021
Microbiota profiles measure the structure of microbial communities in a defined environment (known as microbiomes). In the past decade, microbiome research has focused on health applications as a result of which the gut microbiome has been implicated in the development of a broad range of diseases such as obesity, inflammatory bowel disease, and major ...
arxiv  

Engineering Magnetotactic Bacteria as Medical Microrobots

Advanced Materials, EarlyView.
Magnetotactic bacteria (MTB) are living microorganisms that produce magnetosomes for navigation using the Earth's geomagnetic field. Their built‐in magnetic components, along with their intrinsic and/or modified biological functions, make them one of the most promising platforms for making future living and programmable microrobots.
Jiaqi Wang, Yi Xing, Michael Ngatio, Paulina Bies, Lu Lucy Xu, Liuxi Xing, Ahmed Zarea, Ashley V. Makela, Christopher H. Contag, Jinxing Li   +9 more
wiley   +1 more source

Network analysis of a complex disease: the gut microbiota in the inflammatory bowel disease case [PDF]

arXiv, 2022
Inflammatory bowel diseases (IBD) are complex diseases in which the gut microbiota is attacked by the immune system of genetically predisposed subjects when they are exposed to yet unclear environmental factors. The complexity of this class of diseases makes them suitable to be represented and studied with network science.
arxiv  

Epigenomics and the Microbiota [PDF]

Toxicologic Pathology, 2014
The mammalian gastrointestinal tract is home to trillions of commensal microorganisms that collectively make up the intestinal microbiota. These microbes are important environmental factors that regulate homeostasis, and alterations in the composition of the microbiota have been associated with several diseases, including inflammatory bowel disease ...
openaire   +3 more sources

A Systematic Study of Staphylococcus aureus Biofilm Formation on Thiol‐Ene Polymers: Toward the Development of Microfluidic Bacterial Biofilm Models

Advanced Materials Interfaces, EarlyView.
This work presents a systematic characterization of an emerging polymer platform, off‐stoichiometry thiol‐ene, in terms of its ability to support the formation, growth, and metabolic activity of Staphylococcus aureus biofilms. The findings indicate that thiol‐enes promote S.
Jéssica Amorim, Emil Rosqvist, Cristina D. Cruz, Markus Haapala, Jouko Peltonen, Päivi Tammela, Tiina M. Sikanen   +6 more
wiley   +1 more source