Results 91 to 100 of about 24,781 (265)
Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer. [PDF]
, 2019 Many bacterial pathogens can cause septicemia and spread from the bloodstream into internal organs. During leptospirosis, individuals are infected by contact with Leptospira-containing animal urine-contaminated water.
Fang, Jia-Qi +7 more
core +1 more source
Deformability of Human Mesenchymal Stem Cells Is Dependent on Vimentin Intermediate Filaments [PDF]
, 2017 Mesenchymal stem cells (MSCs) are being studied extensively due to their potential as a therapeutic cell source for many load-bearing tissues. Compression of tissues and the subsequent deformation of cells are just one type physical strain MSCs will need
Bolten, Zachary T. +3 more
core +1 more source
Small Structures, EarlyView.Micro/nanorobots have been developed and deployed, revealing their state‐of‐the‐art applications in pollution detection and remediation. Innovative research progress includes collective behaviors, advanced propulsion mechanisms, and functionalization strategies that enhance their efficiency in diverse and complex aquatic environments, pointing toward ...
Yingyi Gan, Bin Wang, Yuan Lu
wiley +1 more source
Down-regulation of myopodin expression reduces invasion and motility of PC-3 prostate cancer cells [PDF]
, 2009 Enhanced motility of cancer cells by remodelling of the actin cytoskeleton is crucial in the process of cancer cell invasion and metastasis. Although several studies propose a tumor suppressor role for the actin bundling protein myopodin, it was also ...
Bracke, Marc +5 more
core +1 more source
Acoustically Responsive Nanofibrous Scaffolds with 3D Hierarchy for Tympanic Membrane Regeneration
Small Structures, EarlyView.This study investigates the influence of molecular, hierarchical, and acoustical stimulation on biofabricated tympanic membrane (TM) scaffolds within a custom‐built bioreactor mimicking the native tissue niche. It demonstrates that synergistically integrated bioactive agents, 3D hierarchical patterns, and sound waves promote the formation of an aligned
Shivesh Anand +5 more
wiley +1 more source
Frontiers in Endocrinology, 2016 The post-translational modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAc) is regulated by a unique couple of enzymes. O-GlcNAc transferase (OGT) transfers the GlcNAc residue from UDP-GlcNAc, the final product of the hexosamine ...
AGATA eSTEENACKERS +9 more
doaj +1 more source
Cancer Science, EarlyView.We revealed the pivotal role of EVs‐mediated miR‐222 inhibition in modulating adriamycin resistance through post‐transcriptional regulation. Through the systematic implementation of Engineered EVs containing targeted miRNA mimics and inhibitors, we successfully delineated the specific contribution of EVs‐derived miR‐222 to drug resistance phenotypes in
Sujin Yang +8 more
wiley +1 more source
Conserved expression of vertebrate microvillar gene homologs in choanocytes of freshwater sponges [PDF]
, 2016 International audienceBackground: The microvillus is a versatile organelle that serves important functions in disparate animal cell types. However, from a molecular perspective, the microvillus has been well studied in only a few, predominantly ...
Alexandre Alié +5 more
core +6 more sources
Cell Proliferation, EarlyView.Large segmental bone defects can result in non‐union of fractures and present a formidable challenge in clinical management. This study aims to investigate the role of mechanical stimulation in regulating osteogenic differentiation of stem cells via the mechanosensitive protein PDLIM5, thereby promoting bone regeneration and repair.
Yuchao Yang +13 more
wiley +1 more source
Hsp27 anti-sense oligonucleotides sensitize the microtubular cytoskeleton of Chinese hamster ovary cells grown at low pH to 42 degrees C-induced reorganization [PDF]
, 2004 Chinese hamster ovary (CHO) cells maintained in vitro at pH 6.7 were used to model cells in the acidic environment of tumours. CHO cells grown at pH 6.7 develop thermotolerance during 42 degrees C heating at pH 6.7 and their cytoskeletal systems are ...
Coss, Ronald A. +5 more
core +1 more source