Results 81 to 90 of about 334,601 (325)

Modulation of adult-born neurons in the inflamed hippocampus. [PDF]

open access: yes, 2013
Throughout life new neurons are continuously added to the hippocampal circuitry involved with spatial learning and memory. These new cells originate from neural precursors in the subgranular zone of the dentate gyrus, migrate into the granule cell layer,
Belarbi, Karim, Rosi, Susanna
core   +2 more sources

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

open access: yesAdvanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang   +9 more
wiley   +1 more source

From traumatic childhood to cocaine abuse: the critical function of the immune system [PDF]

open access: yes, 2018
Background: Experiencing traumatic childhood is a risk factor for developing substance use disorder (SUD), but the mechanisms that underlie this relationship have not been determined.
Aricò, Eleonora   +17 more
core   +1 more source

Microglia-mediated drug resistance by hijacking drug substances from glioma cells [PDF]

open access: green, 2023
Sheng‐Yan Wu   +5 more
openalex   +1 more source

Microglia and neuroprotection [PDF]

open access: yesJournal of Neurochemistry, 2015
AbstractMicroglia were first identified over a century ago, but our knowledge about their ontogeny and functions has significantly expanded only recently. Microglia colonize the central nervous system (CNS) in utero and play essential roles in brain development.
Zhihong Chen, Bruce D. Trapp
openaire   +2 more sources

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati   +2 more
wiley   +1 more source

Aged lipid‐laden microglia display impaired responses to stroke

open access: yesEMBO Molecular Medicine, 2022
Microglial cells of the aged brain manifest signs of dysfunction that could contribute to the worse neurological outcome of stroke in the elderly. Treatment with colony‐stimulating factor 1 receptor antagonists enables transient microglia depletion that ...
Maria Arbaizar‐Rovirosa   +6 more
doaj   +1 more source

Membrane protein remodeling in microglia exposed to amyloid peptides [PDF]

open access: yes, 2016
Infection, neurodegeneration, and other conditions associated with loss of brain homeostasis, induce changes in microglial morphology, gene expression and function, generally referred to as “activation”.
Correani, Virginia   +7 more
core  

Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons [PDF]

open access: yes, 2017
The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders.
Alhouayek M   +183 more
core   +1 more source

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