Results 11 to 20 of about 29,597 (330)

3D-assembled microneedle ion sensor-based wearable system for the transdermal monitoring of physiological ion fluctuations

Microsystems & Nanoengineering, 2023
Monitoring human health is of considerable significance in biomedicine. In particular, the ion concentrations in blood are important reference indicators related to many diseases.
Xinshuo Huang, Shantao Zheng, Baoming Liang, Mengyi He, Feifei Wu, Jingbo Yang, Hui-jiuan Chen, Xi Xie   +7 more
doaj   +1 more source

Determination of Transdermal Rate of Metallic Microneedle Array through an Impedance Measurements-Based Numerical Check Screening Algorithm

Micromachines, 2022
Microneedle systems have been widely used in health monitoring, painless drug delivery, and medical cosmetology. Although many studies on microneedle materials, structures, and applications have been conducted, the applications of microneedles often ...
Jingshan Mo, Junqing Liu, Shuang Huang, Baoming Liang, Xinshuo Huang, Cheng Yang, Meiwan Chen, Jing Liu, Tong Zhang, Xi Xie, Jun Guo, Fanmao Liu, Hui-Jiuan Chen   +12 more
doaj   +1 more source

An overview of microneedle applications, materials, and fabrication methods

Beilstein Journal of Nanotechnology, 2021
Microneedle-based microdevices promise to expand the scope for delivery of vaccines and therapeutic agents through the skin and withdrawing biofluids for point-of-care diagnostics – so-called theranostics.
Zahra Faraji Rad, Philip D. Prewett, Graham J. Davies   +2 more
doaj   +1 more source

Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle.

PLoS ONE, 2022
Microneedle patches are a promising source for transdermal diffusion of macromolecules and are designed to painlessly penetrate the skin. In this study, a biodegradable chitosan microneedle patch to deliver meloxicam for managing pain in cattle was ...
David A Castilla-Casadiego, Katherine A Miranda-Muñoz, Jesse L Roberts, Anne D Crowell, David Gonzalez-Nino, Dipankar Choudhury, Frank O Aparicio-Solis, Shannon L Servoss, Adrianne M Rosales, Gary Prinz, Min Zou, Yuntao Zhang, Johann F Coetzee, Lauren F Greenlee, Jeremy Powell, Jorge Almodovar   +15 more
doaj   +1 more source

Continuous Glucose Monitoring System Based on Percutaneous Microneedle Array

Micromachines, 2022
A continuous blood glucose monitoring system (CGMS) which include a microneedle-array blood glucose sensor, a circuit module, and a transmission module placed in a wearable device is developed in this research.
Ming-Nan Chien, Yu-Jen Chen, Chin-Han Bai, Jung-Tung Huang   +3 more
doaj   +1 more source

Hydrogel-Crosslinked Microneedles Based on Microwave-Assisted Drying Method

Advances in Polymer Technology, 2022
We present a method and several applications for the synthesis of hydrogel-crosslinked microneedle arrays utilizing microwave-assisted drying, ensuring a significant reduction in reaction preparation time while maintaining quality.
Dongyu Chen, Yu Zhang, Xiaoke Chen, Qiyao He, Tianwei Wu, Xiaoping Cao, Jing Liu, Xueqiu You   +7 more
doaj   +1 more source

Fabricating High-Resolution and High-Dimensional Microneedle Mold through the Resolution Improvement of Stereolithography 3D Printing

Pharmaceutics, 2022
Microneedles are transdermal drug delivery tools that can be fabricated simply, economically, and rapidly using SLA 3D printing. However, SLA 3D printing has a limitation in that the resolution is slightly lowered when the microneedle is precisely ...
Sangmin Choo, SungGiu Jin, JaeHwan Jung
doaj   +1 more source

Integrated Lithographic Molding for Microneedle-Based Devices [PDF]

, 2007
This paper presents a new fabrication method consisting of lithographically defining multiple layers of high aspect-ratio photoresist onto preprocessed silicon substrates and release of the polymer by the lost mold or sacrificial layer technique, coined ...
Altpeter, Dominique M., Berenschot, Erwin J.W., Berg, Albert van den, Boer, Meint J. de, Elwenspoek, Miko, Lüttge, Regina, Vrouwe, Elwin X.   +6 more
core   +7 more sources

Development of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants

Scientific Reports, 2022
Due to the continuously mutating nature of the H3N2 virus, two aspects were considered when preparing the H3N2 microneedle vaccines: (1) rapid preparation and (2) cross-protection against multiple antigenic variants.
Yura Shin, Jeonghun Kim, Jong Hyeon Seok, Heedo Park, Hye-Ran Cha, Si Hwan Ko, Jae Myun Lee, Man-Seong Park, Jung-Hwan Park   +8 more
doaj   +1 more source

Synthesis and characterization of PVP microneedle patch using metal bioelectrodes for novel drug delivery system

Materials & Design, 2021
In this study, we prepared a novel microneedle patch using metal bioelectrodes that provide excellent mechanical properties, drug-delivery efficiency, and biocompatibility at the same time.
Su-Jin Yang, Jin-Oh Jeong, Youn-Mook Lim, Jong-Soek Park   +3 more
doaj   +1 more source