Results 11 to 20 of about 36,831 (386)

Microneedles in Action: Microneedling and Microneedles-Assisted Transdermal Delivery

open access: yesPolymers, 2022
Human skin is a multilayered physiochemical barrier protecting the human body. The stratum corneum (SC) is the outermost keratinized layer of skin through which only molecules with less or equal to 500 Da (Dalton) in size can freely move through the skin.
Lim, Dong-Jin, Kim, Hong-Jun
openaire   +2 more sources

Microneedle, bio-microneedle and bio-inspired microneedle: A review [PDF]

open access: yesJournal of Controlled Release, 2017
Microneedles (MNs) are micro-scale needles used for drug delivery and other targets. Micro-scale size endows them with many advantages over hypodermic needles, including painlessness, minimal invasiveness and convenient operation, but it may also lead to risk of mechanical failures, which should be prevented in the clinical applications of MNs.
Chengwei Wu, G. J. Ma
openaire   +2 more sources

Microneedle Optimization: Toward Enhancing Microneedle's Functionality and Breaking the Traditions

open access: yesSmall Structures
Microneedles hold remarkable potential for providing convenient and unique solutions for disease diagnosis and therapy. However, their integration into clinical practices has been slow, primarily due to the challenge of developing models that meet the ...
Elham Lori Zoudani   +2 more
doaj   +3 more sources

Fluorescent-based biodegradable microneedle sensor array for tether-free continuous glucose monitoring with smartphone application

open access: yesScience Advances, 2023
Continuous glucose monitoring (CGM) allows patients with diabetes to manage critical disease effectively and autonomously and prevent exacerbation.
Mingyu Sang   +13 more
semanticscholar   +1 more source

Integrated Lithographic Molding for Microneedle-Based Devices [PDF]

open access: yes, 2007
This paper presents a new fabrication method consisting of lithographically defining multiple layers of high aspect-ratio photoresist onto preprocessed silicon substrates and release of the polymer by the lost mold or sacrificial layer technique, coined ...
Altpeter, Dominique M.   +6 more
core   +7 more sources

Microneedle system for tissue engineering and regenerative medicine

open access: yesExploration, 2023
Global increasing demand for high life quality and length facilitates the development of tissue engineering and regenerative medicine, which apply multidisciplinary theories and techniques to achieve the structural reconstruction and functional recovery ...
Yixin Zhang   +8 more
semanticscholar   +1 more source

An overview of microneedle applications, materials, and fabrication methods

open access: yesBeilstein Journal of Nanotechnology, 2021
Microneedle-based microdevices promise to expand the scope for delivery of vaccines and therapeutic agents through the skin and withdrawing biofluids for point-of-care diagnostics – so-called theranostics.
Zahra Faraji Rad   +2 more
doaj   +1 more source

Hydrogel-Crosslinked Microneedles Based on Microwave-Assisted Drying Method

open access: yesAdvances in Polymer Technology, 2022
We present a method and several applications for the synthesis of hydrogel-crosslinked microneedle arrays utilizing microwave-assisted drying, ensuring a significant reduction in reaction preparation time while maintaining quality.
Dongyu Chen   +7 more
doaj   +1 more source

Determination of Transdermal Rate of Metallic Microneedle Array through an Impedance Measurements-Based Numerical Check Screening Algorithm

open access: yesMicromachines, 2022
Microneedle systems have been widely used in health monitoring, painless drug delivery, and medical cosmetology. Although many studies on microneedle materials, structures, and applications have been conducted, the applications of microneedles often ...
Jingshan Mo   +12 more
doaj   +1 more source

Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle.

open access: yesPLoS ONE, 2022
Microneedle patches are a promising source for transdermal diffusion of macromolecules and are designed to painlessly penetrate the skin. In this study, a biodegradable chitosan microneedle patch to deliver meloxicam for managing pain in cattle was ...
David A Castilla-Casadiego   +15 more
doaj   +1 more source

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