Results 21 to 30 of about 36,831 (386)

Fabricating High-Resolution and High-Dimensional Microneedle Mold through the Resolution Improvement of Stereolithography 3D Printing

open access: yesPharmaceutics, 2022
Microneedles are transdermal drug delivery tools that can be fabricated simply, economically, and rapidly using SLA 3D printing. However, SLA 3D printing has a limitation in that the resolution is slightly lowered when the microneedle is precisely ...
Sangmin Choo, SungGiu Jin, JaeHwan Jung
doaj   +1 more source

Development of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants

open access: yesScientific Reports, 2022
Due to the continuously mutating nature of the H3N2 virus, two aspects were considered when preparing the H3N2 microneedle vaccines: (1) rapid preparation and (2) cross-protection against multiple antigenic variants.
Yura Shin   +8 more
doaj   +1 more source

Continuous Glucose Monitoring System Based on Percutaneous Microneedle Array

open access: yesMicromachines, 2022
A continuous blood glucose monitoring system (CGMS) which include a microneedle-array blood glucose sensor, a circuit module, and a transmission module placed in a wearable device is developed in this research.
Ming-Nan Chien   +3 more
doaj   +1 more source

Sampling Dermal Interstitial Fluid Using Microneedles: A Review of Recent Developments in Sampling Methods and Microneedle‐Based Biosensors

open access: yesAdvanced Materials Interfaces, 2023
Although interstitial fluid (ISF) is recognized as an important source of biomarkers, it is difficult and time‐consuming to extract, thus limiting its use in medical diagnostic and clinical settings.
K. Saifullah, Zahra Faraji Rad
semanticscholar   +1 more source

A 3D-printed microfluidic-enabled hollow microneedle architecture for transdermal drug delivery. [PDF]

open access: yes, 2019
Embedding microfluidic architectures with microneedles enables fluid management capabilities that present new degrees of freedom for transdermal drug delivery.
Akhtar, Farooq   +11 more
core   +1 more source

Engineering Microneedle Patches for Improved Penetration: Analysis, Skin Models and Factors Affecting Needle Insertion

open access: yesNano-Micro Letters, 2021
Factors affecting microneedle insertion into skin are reviewed. The use of artificial and computational skin models for the simulation of needle insertion is summarized.
Pooyan Makvandi   +10 more
semanticscholar   +1 more source

Microneedle Patch Delivery of PROTACs for Anti-Cancer Therapy.

open access: yesACS Nano, 2023
Proteolysis-targeting chimera (PROTAC) is an emerging technique for degrading disease-related proteins. However, the current PROTACs suffer from inadequate solubility and lack of organ targeting, which has hampered their druggability.
Xiao Cheng, Shiqi Hu, Ke Cheng
semanticscholar   +1 more source

Microneedling: a review

open access: yesRevista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery, 2020
Introduction: Microneedling, also called percutaneous collagen induction therapy (PCIT), is a technique applied with an equipment called roller. It is suitable for rejuvenation, alopecia, all types of scars, acne, photo rejuvenation, stretch marks, skin flaccidity, melasma, expression wrinkles, and improvement of the general aspect of the skin ...
Adriana Da Silva Ferreira   +2 more
openaire   +3 more sources

Three-Dimensional (3D) Printed Microneedles for Microencapsulated Cell Extrusion [PDF]

open access: yes, 2018
Cell-hydrogel based therapies offer great promise for wound healing. The specific aim of this study was to assess the viability of human hepatocellular carcinoma (HepG2) cells immobilized in atomized alginate capsules (3.5% (w/v) alginate, d = 225 µm ...
Bouzos, Evangelia   +6 more
core   +3 more sources

Microneedle array design determines the induction of protective memory CD8+ T cell responses induced by a recombinant live malaria vaccine in mice. [PDF]

open access: yesPLoS ONE, 2011
Vaccine delivery into the skin has received renewed interest due to ease of access to the immune system and microvasculature, however the stratum corneum (SC), must be breached for successful vaccination.
John B Carey   +9 more
doaj   +1 more source

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