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2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2007 This research paper was performed to study and utilizes two kinds of materials which match with two different fabrications in order to design an ideal shape of microneedles. The technology employs the polymer microneedles and the silicon microneedles with the height of 236 mum and 350 mum respectively.
Chin-Chun Hsu +3 more
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Advances of Microneedles in Biomedical Applications [PDF]
Molecules, 2021 A microneedle (MN) is a painless and minimally invasive drug delivery device initially developed in 1976. As microneedle technology evolves, microneedles with different shapes (cone and pyramid) and forms (solid, drug-coated, hollow, dissolvable and hydrogel-based microneedles) have been developed.
Danfeng Xu +4 more
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Inhibition and relaxation of sea urchin sperm flagella by vanadate [PDF]
, 1980 Direct measurements of the stiffness (elastic bending resistance) of demembranated sera urchin sperm flagella were made in the presence of MgATP2- and vanadate.
Okuno, Makoto
core +3 more sources
ACS Sensors, 2023 Microneedle lactate sensors may be used to continuously measure lactate concentration in the interstitial fluid in a minimally invasive and pain-free manner.
D. M. Freeman +9 more
semanticscholar +1 more source
Nanoscale Advances, 2020 This review summarizes recent developments in microneedle-based bioassays.
Wujin Sun +4 more
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Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]
, 2016 Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana +3 more
core +2 more sources
Nano-Micro Letters, 2021 Out-of-plane microneedle structures are widely used in various applications such as transcutaneous drug delivery and neural signal recording for brain machine interface.
Hyeonhee Roh +6 more
doaj +1 more source
Microneedle for transdermal drug delivery: current trends and fabrication
Journal of Pharmaceutical Investigation, 2021 Transdermal delivery has the advantage of bypassing the first-pass effect and allowing sustained release of the drug. However, the drug delivery is limited owing to the barrier created by the stratum corneum.
J. Jung, S. Jin
semanticscholar +1 more source
Facial Plastic Surgery Clinics of North America, 2020 Microneedle radiofrequency (RF) is a breakthrough in targeting skin laxity and rhytids that provides direct in situ delivery, impedance measurements, temperature measurements, energy delivery controls, and targeting of various skin depths to achieve desired clinical outcomes.
openaire +3 more sources
Microneedle-Based Vaccines [PDF]
, 2009 The threat of pandemic influenza and other public health needs motivate the development of better vaccine delivery systems. To address this need, microneedles have been developed as micron-scale needles fabricated using low-cost manufacturing methods that administer vaccine into the skin using a simple device that may be suitable for self ...
John A. Mikszta +3 more
openaire +3 more sources