Results 41 to 50 of about 29,597 (330)

Current advancements in microneedle technology for therapeutic and biomedical applications

Sensors International
Microneedle technology has gained large interest as an innovative biomedical device to deliver molecules to the targeted site through the skin layers. Microneedle consists of microscale needle with a specific length about 0.1–1 mm.
Olivia Sen, Poulami Poddar, Poulami Sarkar, Sanchita Das, Sreejan Manna   +4 more
doaj   +1 more source

Development of Microneedle Patch Loaded with Bacopa monnieri Solid Lipid Nanoparticles for the Effective Management of Parkinson’s Disease

Bioinorganic Chemistry and Applications, 2022
The demand for drug delivery systems (DDS) to treat Parkinson’s disease (PD) is still high, and microneedle (MN) assisted transdermal DDS offers enormous potential.
Delna Joy, Jobin Jose, Shabana Bibi, Akshay Bandiwadekar, Gopika Gopan, Clara Mariana Gonçalves Lima, Talha Bin Emran, Fahad A. Alhumaydhi, Harsha Ashtekar, Sandeep D. S, Carlos Adam Conte-Junior   +10 more
doaj   +1 more source

Wireless sEMG System with a Microneedle-Based High-Density Electrode Array on a Flexible Substrate [PDF]

, 2019
Surface electromyography (sEMG) signals reflect muscle contraction and hence, can provide information regarding a user's movement intention. High-density sEMG systems have been proposed to measure muscle activity in small areas and to estimate ...
CHA, KYOUNG JE, CHUNG, WAN KYUN, GANG, YONG GU, KIM, DONG SUNG, KIM, MINJAE   +4 more
core   +1 more source

Transdermal Polymeric Microneedle Sensing Platform for Fentanyl Detection in Biofluid

Biosensors, 2022
Opioid drugs are extremely potent synthetic analytes, and their abuse is common around the world. Hence, a rapid and point-of-need device is necessary to assess the presence of this compound in body fluid so that a timely countermeasure can be provided ...
Pratik Joshi, Parand R. Riley, Rupesh Mishra, Sina Azizi Machekposhti, Roger Narayan   +4 more
doaj   +1 more source

A Bio-Inspired Swellable Microneedle Adhesive for Mechanical Interlocking with Tissue [PDF]

, 2014
Achieving significant adhesion to soft tissues while minimizing tissue damage poses a considerable clinical challenge. Chemical-based adhesives require tissue-specific reactive chemistry, typically inducing a significant inflammatory response.
Bouma, Brett E., Cho, Woo Kyung, Karp, Jeffrey M., O'Cearbhaill, Eoin D., Park, Kyeng Min, Pomahac, Bohdan, Sisk, Geoffroy C., Villiger, Martin, Yang, Seung Yun   +8 more
core   +1 more source

Microneedling with dermaroller

Journal of Cutaneous and Aesthetic Surgery, 2009
Microneedling with dermaroller is a new treatment modality for the treatment of scars, especially acne scars, stretch marks, wrinkles, and for facial rejuvenation. It is a simple and relatively cheap modality that also can be used for transdermal drug delivery.
openaire   +2 more sources

Strain‐Activated Photo‐Dehalogenation Unlocks Low‐Energy One and Two‐Photon 3D Microfabrication

Advanced Functional Materials, EarlyView.
5,14‐NMI‐Cz acts, conversely to its 7,10‐NMI‐Cz(7,10‐'dibromo‐2‐(2,6‐diisopropylphenyl)‐1H‐benzo[lmn]carbazolo[9,1‐bc][2,8]phenanthroline‐1,3(2H)‐dione) counterpart, as modular photoinitiator with panchromatic photoactivity, featuring a weak C–Br bond from geometric strain for efficient Type I & II initiation. These studies demonstrate applicability of
Kacper Piskorz, Katarzyna Starzak, Malgorzata Noworyta, Konrad Cyprych, Krzysztof Bartkowski, Zahra Badri, Sukhvinder Dhiman, Cina Foroutan‐Nejad, Jaroslaw Mysliwiec, Marcin Lindner, Joanna Ortyl   +10 more
wiley   +1 more source

Flexible and Stretchable Microneedle Patches with Integrated Rigid Stainless Steel Microneedles for Transdermal Biointerfacing. [PDF]

PLoS ONE, 2016
This paper demonstrates flexible and stretchable microneedle patches that combine soft and flexible base substrates with hard and sharp stainless steel microneedles.
Mina Rajabi, Niclas Roxhed, Reza Zandi Shafagh, Tommy Haraldson, Andreas Christin Fischer, Wouter van der Wijngaart, Göran Stemme, Frank Niklaus   +7 more
doaj   +1 more source

Wearable microneedle-based colorimetric and fluorescence sensing for transdermal diagnostics

Talanta Open, 2023
Interstitial fluid is a readily accessible source of biomarkers for various diseases, providing a less invasive and more convenient option than traditional blood or tissue sampling methods.
Jiraporn Leanpolchareanchai, Nantana Nuchtavorn   +1 more
doaj   +1 more source

Towards pain-free diagnosis of skin diseases through multiplexed microneedles: biomarker extraction and detection using a highly sensitive blotting method [PDF]

, 2015
Immunodiagnostic microneedles provide a novel way to extract protein biomarkers from the skin in a minimally invasive manner for analysis in vitro.
A Bhargav, AA Ansari, AV Romanyuk, B Yeow, C Ericsson, CG Li, DA Muller, DV McAllister, G Gremel, HS Gill, JM Skehel, JR Lakowicz, JW Coffey, KT Lee, L Fuertes, L Fuertes, LM Strambini, LM Strambini, M Pilar Martin Del, MI Haq, N Cai, NC Shaner, RF Donnelly, SM Bal, SR Corrie, T-M Tuan-Mahmood, W Schramm, Y Zhu, Y-C Kim   +28 more
core   +2 more sources