Results 71 to 80 of about 29,597 (330)

Inkjet printing of insulin microneedles for transdermal delivery [PDF]

open access: yes, 2015
Inkjet printing technology was used to apply insulin polymeric layers on metal microneedles for transdermal delivery. A range of various polymers such as gelatin (GLN), polyvinyl caprolactame-polyvinyl acetate-polyethylene glycol (SOL), poly(2-ethyl-2 ...
Douroumis, Dennis   +4 more
core   +1 more source

Porous Coatings by Vapor Sublimation and Deposition for Molecular Channeling and Filtration in an Interstitial Fluid Microfiltration Device

open access: yesAdvanced Healthcare Materials, EarlyView.
A vapor‐based porous coating applied within nitinol tubes demonstrated complete suppression of cellular and tissue ingrowth, overcoming a major limitation of implantable interstitial fluid collection devices. Molecular channeling and diffusion are analyzed with probe molecules, showing reliable transport in vitro and in vivo. The coating also achieved >
Yu‐Ming Chang   +8 more
wiley   +1 more source

Assessment of solid microneedle rollers to enhance transmembrane delivery of doxycycline and inhibition of MMP activity

open access: yesDrug Delivery, 2017
Many chronic wounds exhibit high matrix metalloproteinase (MMP) activity that impedes the normal wound healing process. Intradermal delivery (IDD) of sub-antimicrobial concentrations of doxycycline, as an MMP inhibitor, could target early stages of ...
Abbie Omolu   +2 more
doaj   +1 more source

Aerogel keystones: extraction of complete hypervelocity impact events from aerogel collectors

open access: yes, 2003
In January 2006, the Stardust mission will return the first samples from a solid solar-system body since Apollo, and the first samples of contemporary interstellar dust ever collected.
Brennan   +10 more
core   +1 more source

Hydrodynamic gene delivery in human skin using a hollow microneedle device [PDF]

open access: yes, 2017
Microneedle devices have been proposed as a minimally invasive delivery system for the intradermal administration of nucleic acids, both plasmid DNA (pDNA) and siRNA, to treat localised disease or provide vaccination.
Birchall, J. C.   +12 more
core   +5 more sources

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

open access: yesAdvanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz   +3 more
wiley   +1 more source

Two-photon polymerization based reusable master template to fabricate polymer microneedles for drug delivery

open access: yesMethodsX, 2023
Microneedle patches have been widely used in a minimally invasive manner for various drug delivery applications. However, for developing these microneedle patches, master molds are required, which are generally made of metal and are very expensive.
Mamatha M. Pillai   +2 more
doaj   +1 more source

Inkjet printing of transdermal microneedles for the delivery of anticancer agents [PDF]

open access: yes, 2015
A novel inkjet printing technology is introduced as a process to coat metal microneedle arrays with three anticancer agents 5-fluororacil, curcumin and cisplatin for transdermal delivery.
Arora   +36 more
core   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman   +12 more
wiley   +1 more source

On Myosin II dynamics in the presence of external loads

open access: yes, 2005
We address the controversial hot question concerning the validity of the loose coupling versus the lever-arm theories in the actomyosin dynamics by re-interpreting and extending the phenomenological washboard potential model proposed by some of us in a ...
Buonocore, A.   +5 more
core   +2 more sources

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