Results 81 to 90 of about 29,597 (330)

The Use of a Pressure-Indicating Sensor Film to Provide Feedback upon Hydrogel-Forming Microneedle Array Self-Application In Vivo [PDF]

, 2016
PURPOSE: To evaluate the combination of a pressure-indicating sensor film with hydrogel-forming microneedle arrays, as a method of feedback to confirm MN insertion in vivo. METHODS: Pilot in vitro insertion studies were conducted using a Texture Analyser
Barry, Johanne G., Donnelly, Ryan F., Hanna, Lezley-Anne, McAlister, Emma, O' Neill, Shannon, Quinn, Helen L., Vicente-Perez, Eva M.   +6 more
core   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Safety, tolerability and efficacy of intradermal rabies immunization with DebioJect™. [PDF]

, 2017
In a single-center study, 66 healthy volunteers aged between 18 and 50years were randomized to be immunized against rabies with three different injection routes: intradermal with DebioJect™ (IDJ), standard intradermal with classical needle (IDS), also ...
Bart, P.A., Cachemaille, A., Hart, K., Liberman, J., Pantaleo, G., Piveteau, L.D., Ramaniraka, N., Rettby, N., Vescovo, P., Zanoni, R.   +9 more
core   +2 more sources

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

A flexible and dissolving traditional Chinese medicine microneedle patch for sleep-aid intervention

Heliyon
About a quarter of the world's population suffers from insomnia, and the number of the insomniacs is gradually increasing. However, the current drug therapy and non-drug therapy sleep-aid methods have certain limitations. In general, the sleep-aid effect
Chunhua He, Zewen Fang, Heng Wu, Xiaoping Li, Lianglun Cheng, Yangxing Wen, Juze Lin   +6 more
doaj   +1 more source

Human Growth Hormone Delivery with a Microneedle Transdermal System: Preclinical Formulation, Stability, Delivery and PK of Therapeutically Relevant Doses

Pharmaceutics, 2014
This study evaluated the feasibility of coating formulated recombinant human growth hormone (rhGH) on a titanium microneedle transdermal delivery system, Zosano Pharma (ZP)-hGH, and assessed preclinical patch delivery performance.
Mahmoud Ameri, Miryam Kadkhodayan, Joe Nguyen, Joseph A. Bravo, Rebeca Su, Kenneth Chan, Ahmad Samiee, Peter E. Daddona   +7 more
doaj   +1 more source

Wearable bio and chemical sensors [PDF]

, 2014
Chemical and biochemical sensors have experienced tremendous growth in the past decade due to advances in material chemistry combined with the emergence of digital communication technologies and wireless sensor networks (WSNs) [1].
Anoshkin, Ataman, Badugu, Bandodkar, Bergmann, Bhandari, Byrne, Chandrasekhar, Chen, Chu, Claramunt, Coyle, Coyle, Coyle, Curto, Curto, Derbyshire, Gerard, Guinovart, Hill, Jia, Khodagholy, Kim, Kinkeldei, Li, Li, Lima, Lobnik, Mannoor, Massie, Miller, Miller, Morris, Nilghaz, Nilghaz, Ohashi, Oncescu, O’Mahony, Papacosta, Patterson, Potyrailo, Rebrin, Reches, Sakaguchi, Schazmann, Strambini, Suzuki, Voirin, Whitesides, Windmiller, Xing, Yang   +51 more
core   +1 more source

3D Printed Hydrogel Microneedle Arrays for Interstitial Fluid Biomarker Extraction and Colorimetric Detection [PDF]

, 2023
Mahmood Razzaghi, Amir Seyfoori, Erik Pagan, Esfandyar Askari, Alireza Hassani Najafabadi, Mohsen Akbari   +5 more
openalex   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Efecto de los dispositivos de emisión de microondas, radiofrecuencia no ablativa y ultrasonido microfocalizado en el tratamiento de la hiperhidrosis primaria revisión sistemática de la literatura [PDF]

, 2016
Antecedentes y objetivos: La hiperhidrosis primaria afecta el 2,8% de la población de Estados Unidos. Condición que impacta el desarrollo social de los individuos afectados, ocasionando fobia social. Existen opciones disponibles para el tratamiento de la
Cardona Olmos, Andrea, Parra Ulloa, Diana Catalina   +1 more
core   +1 more source