Results 61 to 70 of about 29,331 (220)

Peningkatan Jumlah Mikronukleus pada Mukosa Gingiva Kelinci Setelah Paparan Radiografi Panoramik

Majalah Kedokteran Gigi Indonesia, 2013
Mikronukleus merupakan salah satu tanda awal terjadinya kerusakan DNA yang ditemukan pada mukosa gingiva manusia setelah paparan radiografi dental panoramik.
Rurie Ratna Shantiningsih, Suwaldi Suwaldi, Indwiani Astuti, Munakhir Mudjosemedi   +3 more
doaj   +1 more source

Cytotoxic and Genotoxic Effects in Buccal Cells of Sandstone Quarry Workers

Journal of Applied Toxicology, EarlyView.
ABSTRACT Mineral extraction poses significant occupational health risks, particularly from respirable crystalline silica exposure. Sandstone quarrying generates substantial dust, yet evidence of its genotoxic effects remains limited. This study investigated cytogenotoxic damage in sandstone quarry workers from southern Brazil using the buccal ...
Ana Carolina de Quadros Duarte, Maria Isabela Toniazzo, Rayne Vallada da Luz, Cleisson Guimarães Bueno, Daniela Müller de Quevedo, Luciano Basso da Silva, Daiane Bolzan Berlese   +6 more
wiley   +1 more source

Micronucleus Assay for Evaluation of Genotoxicity in Potentially Malignant and Malignant Disorders

Journal of Indian Academy of Oral Medicine and Radiology, 2011
Oral cancer is a common malignancy, ranking first among all cancers in Western and Asian countries. It is preceded by some benign lesions or conditions, which are termed precancerous.
Parvathi Devi, V B Thimmarasa, Vishal Mehrotra, Pallak Arora   +3 more
doaj   +1 more source

Ionic liquids: structure–toxicity relationships, predictive toxicology, and sustainable design

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Ionic liquids (ILs) have often been described as green alternatives to conventional solvents because of their negligible vapor pressure and highly tunable properties. However, low volatility does not necessarily translate into environmental safety, as their biological and ecological effects are strongly influenced by molecular structure.
Letícia Zanchet, Letícia Guerreiro da Trindade, Monize Bürck, Gabriela Rosa dos Santos, Matheus Klein, Aryel Heitor Ferreira   +5 more
wiley   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Mutagenicity induced by the hydroalcoholic extract of the medicinal plant Plathymenia reticulata Benth

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
Plathymenia reticulata Benth has an anti-inflammatory effect and is capable of neutralizing the neuromuscular blockade induced by Bothrops jararacussu or Crotalus durissus terrificus venoms, probably by precipitating venom proteins (an effect caused by ...
A Della Torre, LBL Albuquerque, NM Farrapo, Y Oshima-Franco, MG Santos, RVS Tavares, ACD Rodas, CA Dal Belo, CRP Cardoso, EA Varanda, FC Groppo, PS Lopes   +11 more
doaj   +1 more source

EFFECT OF RESVERATROL ON GENOMIC STABILITY IN FANCONI ANEMIA [PDF]

Journal of Environmental Science, 2019
Fanconi anemia is a genetically and phenotypically heterogenous disorder characterized by DNA repair deficiency and telomeric erosion. Different antioxidants have been assessed to regain the chromosomal stability in Fanconi anemia, among those is the ...
Peter S. Fahmy, Mostafa H. Ragab, Amal M. Mohamed, Maha M. Eid, Ghada Y. El- Kamah   +4 more
doaj   +1 more source

Dietary Flavonoid Hyperoside Ameliorates High‐Fat Diet‐Induced Type 2 Diabetes Mellitus by Enhancing Brown Adipose Tissue Thermogenesis, White Adipose Tissue Browning, and Gut Microbiota Remodeling

Phytotherapy Research, EarlyView.
Hyperoside ameliorates metabolic dysfunction in high‐fat diet‐induced type 2 diabetic mice, accompanied by enhanced brown adipose tissue thermogenic activity, inguinal white adipose tissue browning‐related changes, reduced M1 macrophage polarization, and gut microbiota remodeling.
WeiFeng Cai, WenXin Zeng, Yu Luo, Qiang Liu, CuiPing Jiang, YanKui Yi, JieYu Chen, ChunYan Shen   +7 more
wiley   +1 more source

Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption

Environmental Toxicology, EarlyView.
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim, Natanael Alves da Silva, Gabriela Gomes Lima, Igor Rodrigues Vasconcelos, Luciana Souza Ondei, Elisa Flávia Luiz Cardoso Bailão, Antônio Sérgio Nakao de Aguiar, Marcelino Benvindo‐Souza, Leonardo Luiz Borges, Virgínia Damin, Luciane Madureira Almeida   +10 more
wiley   +1 more source

Genotoxicity evaluation of sodium dehydroacetate

Zhongguo shipin weisheng zazhi, 2020
Objective To study the genotoxicity of sodium dehydroacetate (Na-DHA). Methods Five strains of Salmonella Typhimurium (TA97a, TA98, TA100, TA102 and TA1535) were used with the presence and absence of S9 in bacterial reverse mutation test.
Xue GENG, Xiaopeng ZHANG, Yongning LI, Qiannan ZHANG, Haibo LIU, Wenming CUI, Hui YANG, Zhou YU, Xudong JIA   +8 more
doaj   +1 more source